Measles hemagglutinin

Last updated
Hemagglutinin
Identifiers
Organism Measles virus (strain Edmonston)
SymbolH
PDB 2RKC
UniProt P08362

Measles hemagglutinin is a hemagglutinin produced by measles virus. [1] [2] [3]

It attaches to CD46 using a dead neuraminidase domain. [4] [5]

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References

  1. Pan CH, Jimenez GS, Nair N, et al. (August 2008). "Use of Vaxfectin adjuvant with DNA vaccine encoding the measles virus hemagglutinin and fusion proteins protects juvenile and infant rhesus macaques against measles virus". Clin. Vaccine Immunol. 15 (8): 1214–21. doi:10.1128/CVI.00120-08. PMC   2519314 . PMID   18524884.
  2. Tahara M, Takeda M, Shirogane Y, Hashiguchi T, Ohno S, Yanagi Y (May 2008). "Measles virus infects both polarized epithelial and immune cells by using distinctive receptor-binding sites on its hemagglutinin". J. Virol. 82 (9): 4630–7. doi:10.1128/JVI.02691-07. PMC   2293038 . PMID   18287234.
  3. Hashiguchi T, Kajikawa M, Maita N, et al. (December 2007). "Crystal structure of measles virus hemagglutinin provides insight into effective vaccines". Proc. Natl. Acad. Sci. U.S.A. 104 (49): 19535–40. Bibcode:2007PNAS..10419535H. doi: 10.1073/pnas.0707830104 . PMC   2148324 . PMID   18003910.
  4. Colf, LA; Juo, ZS; Garcia, KC (December 2007). "Structure of the measles virus hemagglutinin". Nature Structural & Molecular Biology. 14 (12): 1227–8. doi:10.1038/nsmb1342. PMID   18026116. S2CID   40292.
  5. Nussbaum O, Broder CC, Moss B, Stern LB, Rozenblatt S, Berger EA (June 1995). "Functional and structural interactions between measles virus hemagglutinin and CD46". J. Virol. 69 (6): 3341–9. doi:10.1128/JVI.69.6.3341-3349.1995. PMC   189046 . PMID   7745681.