A by-election for the constituency of Bradford South in the United Kingdom House of Commons was held on 8 December 1949, caused by the death of the incumbent Labour MP Meredith Titterington on 28 October of that year. The result was a hold for the Labour Party, with their candidate George Craddock winning with a majority of 4,022 and 51.3% of the vote.
This was the final parliamentary by-election to be held during the 1945-1950 Parliament.
| Party | Candidate | Votes | % | ±% | |
|---|---|---|---|---|---|
| Labour | George Craddock | 23,335 | 51.3 | −1.2 | |
| National Liberal | John Lightfoot Windle | 19,313 | 42.4 | +9.3 | |
| Independent Liberal | Colin James Canning | 2,882 | 6.3 | N/A | |
| Majority | 4,022 | 8.9 | −10.5 | ||
| Turnout | 45,530 | 74.4 | −2.5 | ||
| Labour hold | Swing | -5.3 | |||