Brad Gilbert and Vince Van Patten were the defending champions but only Gilbert competed that year with Kevin Curren.
Joakim Nyström and Mats Wilander were the defending champions, but lost in the second round to Carl Limberger and Mark Woodforde.
Ken Flach and Kathy Jordan were the defending champions but lost in the quarterfinals to Andy Kohlberg and Patty Fendick.
John Fitzgerald and Anders Järryd were the defending champions but lost in the first round to Jonathan Canter and Bruce Derlin.
Paul Annacone and Christo van Rensburg were the defending champions. Annacone competed alongside Kelly Evernden but lost in the semifinals, while van Rensburg played with Kevin Curren and lost in the quarterfinals.
Darren Cahill and Mark Kratzmann won the title, defeating Udo Riglewski and Michael Stich 7–5, 6–2, in the final.
Paul Annacone and Christo van Rensburg were the defending champions, but lost in the semifinals to Swedes and top seeds Stefan Edberg and Anders Järryd.
Pieter Aldrich and Danie Visser were the defending champions, but lost in the first round to Paul Haarhuis and Mark Koevermans.
Scott Davis and David Pate won the title, defeating Patrick McEnroe and David Wheaton 6–1, 4–6, 6–4, 5–7, 9–7, in the final. This was Pate's first Grand Slam title and final, despite gaining the World No. 1 ranking two weeks earlier.
John Fitzgerald and Anders Järryd lost in the third round to McEnroe and Wheaton. It was their only Grand Slam loss of the year, as they would go on to win the following three majors in 1991.
Ken Flach and Robert Seguso successfully defended their title, defeating John Fitzgerald and Anders Järryd in the final, 6–4, 2–6, 6–4, 7–6(7–3) to win the gentlemen's doubles title at the 1988 Wimbledon Championships.
Rick Leach and Jim Pugh were the defending champions but lost in the first round to Goran Ivanišević and John McEnroe.
Pieter Aldrich and Danie Visser were the defending champions, but decided to not compete this year after winning the Australian Open 2 weeks earlier.
Guy Forget and Yannick Noah were the defending champions, but none competed this year.
Patrick Galbraith and Todd Witsken were the defending champions, but competed this year with different partners.
Patrick Galbraith and Danie Visser were the defending champions, but competed this year with different partners. Galbraith teamed up with Grant Connell and lost in the semifinals to Jim Courier and Mark Knowles, while Visser teamed up with Laurie Warder and lost in the second round, also to Courier and Knowles.
Wally Masur and Jason Stoltenberg were the defending champions, but competed this year with different partners. Masur teamed up with Mark Kratzmann and lost in the semifinals to Jim Grabb and Richey Reneberg, while Stoltenberg teamed up with Todd Nelson and lost in quarterfinals to Pieter Aldrich and Danie Visser.
Scott Davis and David Pate were the defending champions, but lost in the first round to Glenn Michibata and Brad Pearce.
Stefan Edberg and Petr Korda were the defending champions, but lost in the first round to Gary Muller and Danie Visser.
Paul Haarhuis and Mark Koevermans were the defending champions, but competed this year with different partners. Haarhuis teamed up with Jacco Eltingh and lost in the semifinals to Henrik Holm and Anders Järryd, while Koevermans teamed up with Jan Apell and lost in the first round to Javier Sánchez and Daniel Vacek.
Scott Davis and Robert Van't Hof were the defending champions, but faced each other in this edition, with different partners. Davis, teaming up with David Pate, defeated Van't Hof and Andy Kohlberg in the first round. Davis and Pate were eliminated in quarterfinals to Christo Steyn and Danie Visser.
Andre Agassi and Petr Korda were the defending champions, but Agassi chose not to participate. Korda played along Ivan Lendl, but lost in the first round to Neil Borwick and Simon Youl.
Pieter Aldrich and Danie Visser were the defending champions, but Aldrich did not compete this year. Visser teamed up with Gary Muller and lost in the quarterfinals to Nick Brown and Richard Vogel.
Wally Masur 
Ronnie Båthman 
