The 2000–01 Serie A was the 99th season of top-tier Italian football, the 69th in a round-robin tournament. It was contested by 18 teams, for the 13th consecutive season since 1988–89.
The 1996–97 Serie A title was won by Juventus, under head coach Marcello Lippi. Cagliari, Perugia, Hellas Verona and Reggiana were relegated.
The 2000–01 season was the 101st season in Società Sportiva Lazio's history and their 13th consecutive season in the top-flight of Italian football. Lazio were unable to defend their Serie A title won in 2000 after finishing third, but won the Supercoppa Italiana.
Parma Associazione Calcio had a moderately strong season in 2000–01, managing to qualify for the UEFA Champions League, but also losing the final of Coppa Italia and dropping out of the UEFA Cup too early for the board's liking, ultimately leading to coach Alberto Malesani being let go at the end of the season.
During the 2000-01 season A.S. Roma competed in Serie A, Coppa Italia and UEFA Cup.
S.S.C. Napoli returned to Serie A, following a couple of years in Serie B, where the club had rebuilt itself following the disastrous 1997-98 season, when it scored merely 14 points from 34 games.
Associazione Calcio Milan had a poor season in 2000–01, finishing 6th in Serie A with 49 points, and only the scoring touch of Ukrainian striker Andriy Shevchenko saved them from complete humiliation.
During the 2000–01 season Fiorentina competed in Serie A, Coppa Italia and UEFA Cup.
Reggina Calcio made its Serie A debut in the 1999-00 season, ending the season in twelfth place for the southernmost team in the league at the time. The season also saw the definite breakthroughs of Roberto Baronio, Andrea Pirlo, and Mohamed Kallon, leading to all three players joining larger clubs in the summer. The performance also owed much to goalkeeper Massimo Taibi, returning from a poor spell at Manchester United.
Atalanta B.C. returned to Serie A following a two-year absence, and immediately established itself on the top half of the table, finishing in 7th place. Coach Giovanni Vavassori was hailed as the main contributor to the success, having come from the youth side a couple of years before, first promoting the club, and then having such a successful inaugural Serie A campaign. Inter-owned Nicola Ventola scored ten league goals, enough to persuade Inter to take him back, and playmaker Cristiano Doni got his proper breakthrough as well. Experienced Massimo Carrera held the defence together, and was also widely praised, while goalkeeper Ivan Pelizzoli was signed by champions Roma.
Piacenza Calcio once again survived in Serie A, this time being on the brink of relegation, and having to beat Cagliari in Naples in a so-called spareggio to decide which team would stay up. Thanks to a 3–1 victory, Piacenza was able to hang onto their Serie A status, which was all that could be expected from new coach Bortolo Mutti. Despite losing Nicola Caccia to Napoli, Piacenza was able to count on a reliable goal scorer in Pasquale Luiso, who grabbed 14 goals in his debut season in Serie A.
Piacenza Calcio recorded their best ever finish in the top echelon of Italian football, finishing 12th in Serie A, but just two points above the relegation zone. This was in spite of key players Pasquale Luiso (Vicenza) and Eusebio Di Francesco (Roma) leaving the club before the season began.
Piacenza Calcio crashed out of Serie A, following a dismal season. With ex-Inter coach Luigi Simoni at the helm, the club was looking to climb into midtable in Serie A, but the absence of Simone Inzaghi and the ageing of several key players rendered disastrous form, and Simoni was soon sacked. In the end, Piacenza finished rock bottom of the table and their five-year stint in the top flight was ended.
The 2013–14 Coppa Italia, also known as TIM Cup for sponsorship reasons, was the 67th edition of the competition. As in the previous year, 78 clubs have taken part in the tournament. Lazio were the cup holders. Napoli were the winners, thus qualifying for the group stage of the 2014–15 UEFA Europa League.
The 2014–15 Coppa Italia, also known as TIM Cup for sponsorship reasons, was the 68th edition of the national cup in Italian football. Napoli were the defending champions, having won the previous year's final, but were eliminated in the semi-finals by Lazio. Juventus emerged victorious with a 2–1 win in extra time, achieving a record tenth title.
The 2019–20 Coppa Italia was the 73rd edition of the national cup in Italian football.
During the 2000–01 season Brescia Calcio competed in Serie A and Coppa Italia.
The 2001–02 season was Hellas Verona F.C.'s second consecutive season in second division of the Italian football league, the Serie B, and the 99th as a football club.
The 2000–01 season was A.C. Perugia's third consecutive season in top flight of the Italian football league, the Serie A, and the 96th as a football club.