The 2010 Washington Redskins season was the franchise's 79th season in the National Football League (NFL), and their first under new head coach Mike Shanahan, who also began his term as the team's Vice President of Football Operations. The Redskins obtained the 4th pick in the 2010 NFL draft as a result of their 4–12 record from their previous season, which they used to draft Oklahoma tackle Trent Williams. Finishing the season 6–10, the Redskins improved on their 4–12 record from the 2009 season, but were officially eliminated from postseason contention in Week 14. Of the 16 games of the season, only four were decided by more than a single possession.
The 2010 Orlando Predators season was the 19th season for the franchise in the Arena Football League. The team was coached by Pat O'Hara and played their home games at Amway Arena. The Predators clinched a playoff berth for the 18th consecutive season by finishing fourth in the American Conference. In the opening round of the playoffs, the Predators defeated the Jacksonville Sharks with a last-second touchdown to win 73–69. Orlando then traveled to Tampa Bay to face the rival Storm for the third time in the season in the conference championship, but lost 62–63 after a would-be game-winning field goal fell short as time expired.
The 2010 Tampa Bay Storm season was the 23rd season for the franchise in the Arena Football League. The team was coached by Tim Marcum and played their home games at the St. Pete Times Forum.
The 2010 Jacksonville Sharks season was the inaugural season for the franchise in the Arena Football League. The team was coached by Les Moss and played their home games at Jacksonville Veterans Memorial Arena. The Sharks put together a 12–4 record, winning the South division and was also the top team in the American Conference. However, the Sharks lost a back-and-forth game at home to the Orlando Predators in the opening playoff round by a score of 69–73.
The 2010 Alabama Vipers season was the 10th season for the franchise, and the first under their current name, as well as the first in the Arena Football League. The team was coached by Dean Cokinos and played their home games at Von Braun Center. The Vipers failed to make the playoffs after posting a 7–9 record and finishing 5th in the American Conference.
The 2010 Bossier–Shreveport Battle Wings season was the 9th season for the franchise, and the first in the Arena Football League, coming from the AF2, which dissolved following the 2009 season. The team was coached by Jon Norris and played their home games at CenturyTel Center. With a 3–13 record, the Battle Wings failed to qualify for the playoffs, finishing last in the American Conference.
The 2010 Dallas Vigilantes season was the inaugural season for the franchise in the Arena Football League (AFL). With many players of the old Desperados team that put up a 15–1 record in recent years returning, Dallas fans had high hopes for the Vigilantes carrying on with the Desperados' success. However, after a 1–5 start and an altercation with one of his players, head coach Rich Ingold was fired, and replaced by James Fuller for the remainder of the season. Eventually Clint Dolezel was named as head coach for the 2011 season after the Vigilantes went 2–8 in their final ten games to finish the 2010 season 3–13, despite winning their last game of the season on the road, 62–56 against the Bossier–Shreveport Battle Wings. Two of Dallas's three wins that season came on the road.
The 2010 Oklahoma City Yard Dawgz season is the 7th season for the franchise, and the first in the Arena Football League, coming from the AF2, which dissolved following the 2009 season. The team was coached by Sparky McEwen and played their home games at the Cox Convention Center. The Yard Dawgz did not qualify for the postseason after finishing with a 6–10 record and placing 6th in the American Conference.
The 2010 Chicago Rush season was the tenth season for the franchise in the Arena Football League. The team was coached by Mike Hohensee and played their home games at Allstate Arena. For the 10th consecutive season, the Rush qualified for the playoffs. In the conference semifinals, they lost to the Milwaukee Iron, 54–64.
The 2010 Cleveland Gladiators season was the 11th season for the franchise in the Arena Football League, and the second while in Cleveland. The team was coached by Steve Thonn and played their home games at Quicken Loans Arena. The Gladiators missed out on the playoffs by finishing 5th in the National Conference with a 7–9 record.
The 2010 Iowa Barnstormers season was the 10th season for the franchise, and the sixth in the Arena Football League, after three total seasons from 2001–2009 in the AF2, which dissolved following the 2009 season. The team was coached by John Gregory and played their home games at Wells Fargo Arena. The Barnstormers failed to make the playoffs when they finished the regular season 6th in the National Conference with a 7–9 record.
The 2010 Milwaukee Iron season was the second season for the franchise, and the first in the Arena Football League (AFL), coming from the AF2, which dissolved following the 2009 season. The team was coached by Bob Landsee and played their home games at Bradley Center. For the opening round of the playoffs, the Iron played at U.S. Cellular Arena. The Iron won the Midwest Division to qualify for the playoffs, and defeated the Chicago Rush in the conference semifinals, 64–54. Advancing to the National Conference Championship, their season ended after losing on the road to the top-seeded Spokane Shock, 57–60.
The 2010 Arizona Rattlers season was the 19th season for the franchise in the Arena Football League. The team was coached by Kevin Guy and played their home games at US Airways Center. The Rattlers made the playoffs with a 10–6 record, fourth best in the National Conference, but were defeated by the top-seeded Spokane Shock in the conference semifinals, 49–57.
The 2010 Spokane Shock season was the fifth season for the franchise, and the first in the current incarnation of the Arena Football League, coming from the AF2, which dissolved following the 2009 season. The team is coached by Rob Keefe and played their home games at Spokane Veterans Memorial Arena.
The 2010 Utah Blaze season is the 4th season for the franchise in the Arena Football League. The team was coached by Ernesto Purnsley, who was fired on June 1, 2010, with Ron James named as his replacement. Home games are played at the Maverik Center, which was known as the "E Center" prior to being renamed on June 8, 2010. The Blaze missed out on the postseason after finishing the season 2–14, the worst record in the league.
The 2011 Tampa Bay Storm season is the 24th season for the franchise, their 20th in the Tampa Bay region. The team is coached by Dave Ewart and plays home games at the St. Pete Times Forum on the Amalie Motor Oil Field, sponsored by the Amalie Oil Company.
The 2011 Orlando Predators season was the 20th season for the franchise in the Arena Football League. The team was coached by Pat O'Hara. This was the Predators' first season at Amway Center. The Predators finished the regular season 11–7, qualifying for the playoffs for the 19th consecutive season. As the 4th seed in the American Conference, they lost to the Jacksonville Sharks in the conference semifinals, 48–63.
The 2011 Philadelphia Soul season was the 6th season for the franchise in the Arena Football League. The team was coached by Mike Hohensee and played their home games at Wells Fargo Center. This was the first season for the Soul since they won ArenaBowl XXII in 2008, after the league went on hiatus in 2009 and the franchise was not active in 2010. The Soul finished the season 6–12, and missed the playoffs.
The 2011 Chicago Rush season was the 10th season for the franchise in the Arena Football League. The team was coached by Bob McMillen and played their home games at Allstate Arena. The Rush finished the regular season 13–5, qualifying for the playoffs for the 10th consecutive season. As the 2nd seed, they defeated the Dallas Vigilantes 54–41 in the conference semifinals before losing to the Arizona Rattlers 48–54 in the conference championship.
The 2011 Tulsa Talons season was the 12th season for the franchise, and the second in the Arena Football League. The team was coached by Mitch Allner and played their home games at BOK Center. The Talons finished the season 8–10, failing to qualify for the playoffs. This would be the last season for the Talons in Tulsa, Oklahoma. The franchise relocated to San Antonio, Texas following this season.