| 2011 Knoxville Challenger | |
|---|---|
| Date | 8–13 November |
| Edition | 8th |
| Surface | Hard |
| Location | Knoxville, United States |
| Champions | |
| Singles | |
 Jesse Levine | |
| Doubles | |
| Steve Johnson / Austin Krajicek | |
The 2011 Knoxville Challenger was a professional tennis tournament played on hard courts. It was the eighth edition of the tournament which is part of the 2011 ATP Challenger Tour. It took place in Knoxville, United States between 8 and 13 November 2011.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
| USA | Michael Russell | 93 | 1 |
| USA | Bobby Reynolds | 120 | 2 |
 RSA | Rik de Voest | 122 | 3 |
| RSA | Izak van der Merwe | 132 | 4 |
 CAN | Vasek Pospisil | 133 | 5 |
 BLR | Uladzimir Ignatik | 172 | 6 |
| USA | Michael Yani | 177 | 7 |
 AUS | Greg Jones | 192 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry as an alternate into the singles main draw:
The following players received entry as a special exempt into the singles main draw:
The following players received entry from the qualifying draw:
Jesse Levine def. Brian Baker, 6–2, 6–3
Steve Johnson / Austin Krajicek def. Adam Hubble / 
Frederik Nielsen, 3–6, 6–4, [13–11]
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