| Doubles | |
|---|---|
| 2019 Knoxville Challenger | |
| Champions |  Hans Hach Verdugo  Adrián Menéndez Maceiras |
| Runners-up |  Bradley Klahn  Sem Verbeek |
| Final score | 7–6(8–6), 4–6, [10–5] |
Toshihide Matsui and Frederik Nielsen were the defending champions [1] but chose not to defend their title.
Hans Hach Verdugo and Adrián Menéndez Maceiras won the title after defeating Bradley Klahn and Sem Verbeek 7–6(8–6), 4–6, [10–5] in the final.
Sriram Balaji / Jeevan Nedunchezhiyan (first round)
Treat Huey / Jackson Withrow (first round) Robert Galloway / 
Roberto Maytín (quarterfinals)
Luca Margaroli / 
Andrea Vavassori (semifinals)| First round | Quarterfinals | Semifinals | Final | ||||||||||||||||||||||||
| 1 | S Balaji J Nedunchezhiyan | 5 | 4 | ||||||||||||||||||||||||
| M Giron A Lawson | 7 | 6 | M Giron A Lawson | 3 | 6 | [2] | |||||||||||||||||||||
| WC | Andrew Rogers T Sandgren | 4 | 78 | [8] | H Hach Verdugo A Menéndez Maceiras | 6 | 3 | [10] | |||||||||||||||||||
| H Hach Verdugo A Menéndez Maceiras | 6 | 66 | [10] | H Hach Verdugo A Menéndez Maceiras | 77 | 77 | |||||||||||||||||||||
| 4 | L Margaroli A Vavassori | 6 | 6 | 4 | L Margaroli A Vavassori | 63 | 63 | ||||||||||||||||||||
 D King E King | 2 | 3 | 4 | L Margaroli A Vavassori | 6 | 6 | |||||||||||||||||||||
 P Polansky B Schnur | 4 | 2 | WC | S Bangoura M Mmoh | 3 | 3 | |||||||||||||||||||||
| WC | S Bangoura M Mmoh | 6 | 6 | H Hach Verdugo A Menéndez Maceiras | 78 | 4 | [10] | ||||||||||||||||||||
| WC |  Timo Stodder Preston Touliatos | 1 | 4 | B Klahn S Verbeek | 66 | 6 | [5] | ||||||||||||||||||||
| N Pasha M Schnur | 6 | 6 | N Pasha M Schnur | 78 | 3 | [11] | |||||||||||||||||||||
| JC Aragone H Reese | 65 | 67 | 3 | R Galloway R Maytín | 66 | 6 | [9] | ||||||||||||||||||||
| 3 | R Galloway R Maytín | 77 | 79 | N Pasha M Schnur | 2 | 4 | |||||||||||||||||||||
D Novikov  A Siljeström | 6 | 77 | B Klahn S Verbeek | 6 | 6 | ||||||||||||||||||||||
M Krueger  B Rola | 4 | 65 | D Novikov A Siljeström | 3 | 3 | ||||||||||||||||||||||
| B Klahn S Verbeek | 6 | 6 | B Klahn S Verbeek | 6 | 6 | ||||||||||||||||||||||
| 2 | T Huey J Withrow | 3 | 3 | ||||||||||||||||||||||||
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