| Doubles | |
|---|---|
| 2021 Ambato La Gran Ciudad | |
| Champions |  Diego Hidalgo  Cristian Rodríguez |
| Runners-up | Alejandro Gómez  Thiago Agustín Tirante |
| Score | 6–3, 4–6, [10–3] |
This was the first edition of the tournament. [1]
Diego Hidalgo and Cristian Rodríguez won the title after defeating Alejandro Gómez and Thiago Agustín Tirante 6–3, 4–6, [10–3] in the final.
Sergio Galdós / Facundo Mena (first round)
Carlos Gómez-Herrera / Renzo Olivo (quarterfinals) Diego Hidalgo / Cristian Rodríguez (champions)
Andrej Martin / 
Gonçalo Oliveira (semifinals, withdrew)| First round | Quarterfinals | Semifinals | Final | ||||||||||||||||||||||||
| 1 | S Galdós F Mena | 2 | 6 | [8] | |||||||||||||||||||||||
| A Gómez TA Tirante | 6 | 2 | [10] | A Gómez TA Tirante | 6 | 6 | |||||||||||||||||||||
| E Gómez R Quiroz | 6 | 64 | [7] |  B Arias F Zeballos | 3 | 3 | |||||||||||||||||||||
| B Arias F Zeballos | 4 | 77 | [10] | A Gómez TA Tirante | w/o | ||||||||||||||||||||||
| 4 | A Martin G Oliveira | 6 | 77 | 4 | A Martin G Oliveira | ||||||||||||||||||||||
| WC | Á Guillén Meza G Villanueva | 2 | 65 | 4 | A Martin G Oliveira | 6 | 6 | ||||||||||||||||||||
 L Castelnuovo J Nikles | 3 | 2 | E Esteve Lobato O Roca Batalla | 4 | 2 | ||||||||||||||||||||||
| Eduard Esteve Lobato O Roca Batalla | 6 | 6 | A Gómez TA Tirante | 3 | 6 | [3] | |||||||||||||||||||||
A Merino  JA Ore | 5 | 5 | 3 | D Hidalgo C Rodríguez | 6 | 4 | [10] | ||||||||||||||||||||
| A Mendoza Matías Zukas | 7 | 7 | A Mendoza M Zukas | 712 | 3 | [4] | |||||||||||||||||||||
| WC | Juan Pinto Vela Sebastián Sevilla Sevilla | 0 | 0 | 3 | D Hidalgo C Rodríguez | 610 | 6 | [10] | |||||||||||||||||||
| 3 | D Hidalgo C Rodríguez | 6 | 6 | 3 | D Hidalgo C Rodríguez | 77 | 6 | ||||||||||||||||||||
| PR |  J Lenz  G Melzer | 6 | 6 | PR | J Lenz G Melzer | 62 | 4 | ||||||||||||||||||||
| WC | AC March Pol Martín Tiffon | 3 | 3 | PR | J Lenz G Melzer | 77 | 4 | [13] | |||||||||||||||||||
| A González A Menéndez Maceiras | 1 | 61 | 2 | C Gómez-Herrera R Olivo | 64 | 6 | [11] | ||||||||||||||||||||
| 2 | C Gómez-Herrera R Olivo | 6 | 77 | ||||||||||||||||||||||||
Marcelo Arévalo and Miguel Ángel Reyes-Varela were the defending champions but chose not to defend their title.
The 2021 Ambato La Gran Ciudad was a professional tennis tournament played on clay courts. It was the 1st edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Ambato, Ecuador between 20 and 26 September 2021.
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