| Doubles | |
|---|---|
| 2021 Berkeley Tennis Club Challenge | |
| Champions |  Sophie Chang Angela Kulikov |
| Runners-up |  Liang En-shuo  Lu Jiajing |
| Score | 6–4, 6–3 |
Madison Brengle and Sachia Vickery were the defending champions [1] but chose not to participate.
Sophie Chang and Angela Kulikov won the title, defeating Liang En-shuo and Lu Jiajing in the final, 6–4, 6–3.
Dalila Jakupović / 
Hiroko Kuwata (semifinals)
Bárbara Gatica / 
Rebeca Pereira (first round)
Ivana Popovic / Olivia Tjandramulia (semifinals) Liang En-shuo / Lu Jiajing (final)| First round | Quarterfinals | Semifinals | Final | ||||||||||||||||||||||||
| 1 | D Jakupović H Kuwata | 6 | 6 | ||||||||||||||||||||||||
 M Björklund F Di Lorenzo | 2 | 3 | 1 | D Jakupović H Kuwata | 6 | 1 | [10] | ||||||||||||||||||||
| WC | H Giavara  V Ivanov | 2 | 5 | WC | E Bolton J Hart | 4 | 6 | [6] | |||||||||||||||||||
| WC | E Bolton J Hart | 6 | 7 | 1 | D Jakupović H Kuwata | 4 | 4 | ||||||||||||||||||||
| 4 | E-s Liang Jia Lu | 6 | 65 | [11] | 4 | E-s Liang Jia Lu | 6 | 6 | |||||||||||||||||||
| J Aney M Manasse | 2 | 77 | [9] | 4 | E-s Liang Jia Lu | w/o | |||||||||||||||||||||
| UM Arconada L Chirico | w/o | UM Arconada L Chirico | |||||||||||||||||||||||||
| WC | C Chavatipon C Van Nguyen | 4 | E-s Liang Jia Lu | 4 | 3 | ||||||||||||||||||||||
| K Okamura K Volynets | w/o | S Chang A Kulikov | 6 | 6 | |||||||||||||||||||||||
 K Sebov R Ushijima | K Okamura K Volynets | 3 | 3 | ||||||||||||||||||||||||
| R Brantmeier H Chang | 64 | 6 | [7] | 3 | I Popovic O Tjandramulia | 6 | 6 | ||||||||||||||||||||
| 3 | I Popovic O Tjandramulia | 77 | 3 | [10] | 3 | I Popovic O Tjandramulia | 4 | 3 | |||||||||||||||||||
| A Bozovic A Osborne | 1 | 3 | S Chang A Kulikov | 6 | 6 | ||||||||||||||||||||||
| S Chang A Kulikov | 6 | 6 | S Chang A Kulikov | 7 | 6 | ||||||||||||||||||||||
V Duval  M Zacarías | 6 | 6 | V Duval M Zacarías | 5 | 1 | ||||||||||||||||||||||
| 2 | B Gatica R Pereira | 3 | 4 | ||||||||||||||||||||||||
The tournament in Xi'an was a new addition to the ITF Women's Circuit.
The tournament in New Delhi was a new addition to the ITF Women's Circuit.
Noppawan Lertcheewakarn and Lu Jiajing were the defending champions, but both players chose not to participate.
Jada Hart and Ena Shibahara were the defending champions, but both players were ineligible to participate.
Liang En-shuo and Wang Xinyu won the girls' doubles tennis title at the 2018 Australian Open, defeating Violet Apisah and Lulu Sun in the final, 7–6(7–4), 4–6, [10–5].
Caty McNally and Iga Świątek won the girls' doubles tennis title at the 2018 French Open, defeating Yuki Naito and Naho Sato in the final, 6–2, 7–5.
Olga Danilović and Kaja Juvan were the defending champions, but both players chose not to participate.
Natsumi Kawaguchi and Adrienn Nagy won the girls' doubles tennis title at the 2019 Australian Open, defeating Chloe Beck and Emma Navarro in the final, 6–4, 6–4.
Anna Kalinskaya and Viktória Kužmová were the defending champions, but chose not to participate.
Mihaela Buzărnescu was the defending champion, but lost to Daria Kasatkina in the first round.
Zheng Saisai was the defending champion, but lost in the quarterfinals to Ajla Tomljanović.
Dayana Yastremska was the defending champion, but withdrew before the tournament began.
Simona Halep was the defending champion, but chose not to participate.
Caroline Dolehide was the defending champion, having won the previous edition in 2019. She lost in the second round to Katrina Scott.
This was the first edition of the women's event.
The 2021 Berkeley Tennis Club Challenge was a professional women's tennis tournament played on outdoor hard courts. It was the third edition of the tournament which was part of the 2021 ITF Women's World Tennis Tour. It took place in Berkeley, California, United States between 27 September and 3 October 2021.
Kayla Day and Sophia Whittle were the defending champions but chose not to participate.
Robin Anderson was the defending champion but chose to participate at the 2022 Ilkley Trophy instead.
Erina Hayashi and Moyuka Uchijima were the defending champions but Uchijima chose not to participate. Hayashi partnered alongside Kanako Morisaki, but lost to Momoko Kobori and Luksika Kumkhum in the semifinals.
This was the first edition of the tournament.