| Singles | |
|---|---|
| 2021 Copa Sevilla | |
| Champion |  Pedro Martínez |
| Runner-up | Roberto Carballés Baena |
| Score | 6–4, 6–1 |
Alejandro Davidovich Fokina was the defending champion [1] but chose not to defend his title.
Pedro Martínez won the title after defeating Roberto Carballés Baena 6–4, 6–1 in the final.
Pablo Andújar (quarterfinals) Pedro Martínez (champion) Roberto Carballés Baena (final) Carlos Taberner (semifinals) Bernabé Zapata Miralles (second round)
Federico Gaio (second round)
Marcelo Tomás Barrios Vera (semifinals) Lorenzo Giustino (first round)| Semifinals | Final | ||||||||||||
| 7 | Marcelo Tomás Barrios Vera | 1 | 3 | ||||||||||
| 3 | Roberto Carballés Baena | 6 | 6 | ||||||||||
| 3 | Roberto Carballés Baena | 4 | 1 | ||||||||||
| 2 | Pedro Martínez | 6 | 6 | ||||||||||
| 4 | Carlos Taberner | 4 | 3 | ||||||||||
| 2 | Pedro Martínez | 6 | 6 | ||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | P Andújar | 6 | 7 | ||||||||||||||||||||||||
| J Barranco Cosano | 2 | 5 | 1 | P Andújar | 3 | 6 | 6 | ||||||||||||||||||||
| WC | A López San Martín | 6 | 4 | 6 | WC | A López San Martín | 6 | 1 | 4 | ||||||||||||||||||
| Q | Benjamín Winter López | 4 | 6 | 1 | 1 | P Andújar | 61 | 6 | 4 | ||||||||||||||||||
 M Geerts | 3 | 2 | 7 | MT Barrios Vera | 77 | 2 | 6 | ||||||||||||||||||||
 J Draper | 6 | 6 | J Draper | 5r | |||||||||||||||||||||||
| WC | N Sánchez Izquierdo | 6 | 2 | 5 | 7 | MT Barrios Vera | 6 | ||||||||||||||||||||
| 7 | MT Barrios Vera | 4 | 6 | 7 | 7 | MT Barrios Vera | 1 | 3 | |||||||||||||||||||
| 3 | R Carballés Baena | 6 | 3 | 6 | 3 | R Carballés Baena | 6 | 6 | |||||||||||||||||||
| Alt | J Ocleppo | 2 | 6 | 3 | 3 | R Carballés Baena | 6 | 6 | |||||||||||||||||||
| R Ortega Olmedo | 62 | 0 |  A Andreev | 4 | 1 | ||||||||||||||||||||||
| A Andreev | 77 | 6 | 3 | R Carballés Baena | 7 | 77 | |||||||||||||||||||||
| C Gimeno Valero | 0r | Q | L Darderi | 5 | 65 | ||||||||||||||||||||||
| Q | L Darderi | 3 | Q | L Darderi | 6 | 77 | |||||||||||||||||||||
 T Gabashvili | 2 | 1 | 6 | F Gaio | 0 | 61 | |||||||||||||||||||||
| 6 | F Gaio | 6 | 6 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 5 | B Zapata Miralles | 6 | 6 | ||||||||||||||||||||||||
| PR | F Baldi | 3 | 2 | 5 | B Zapata Miralles | 6 | 1 | 4 | |||||||||||||||||||
| GM Moroni | 77 | 6 | GM Moroni | 3 | 6 | 6 | |||||||||||||||||||||
| N Kuhn | 65 | 1 | GM Moroni | 4 | 6 | 5 | |||||||||||||||||||||
 G Oliveira | 2 | 6 | 2 | 4 | C Taberner | 6 | 0 | 7 | |||||||||||||||||||
| PR |  J Lenz | 6 | 4 | 6 | PR | J Lenz | 3 | 3 | |||||||||||||||||||
| Q | Lucas Gerch | 1 | 4 | 4 | C Taberner | 6 | 6 | ||||||||||||||||||||
| 4 | C Taberner | 6 | 6 | 4 | C Taberner | 4 | 3 | ||||||||||||||||||||
| 8 | L Giustino | 0 | 2 | 2 | P Martínez | 6 | 6 | ||||||||||||||||||||
| F Cobolli | 6 | 6 | F Cobolli | 6 | 7 | ||||||||||||||||||||||
| WC | P Llamas Ruiz | 7 | 4 | WC | P Llamas Ruiz | 3 | 5 | ||||||||||||||||||||
 C Ugo Carabelli | 5 | 1r | F Cobolli | 4 | 2 | ||||||||||||||||||||||
| R Brancaccio | 6 | 2 | 77 | 2 | P Martínez | 6 | 6 | ||||||||||||||||||||
| Alt | GA Olivieri | 2 | 6 | 64 | R Brancaccio | 4 | 6 | 4 | |||||||||||||||||||
| Q |  Em Nava | 5 | 4 | 2 | P Martínez | 6 | 4 | 6 | |||||||||||||||||||
| 2 | P Martínez | 7 | 6 | ||||||||||||||||||||||||
Dominic Thiem was the defending champion, but lost in the quarterfinals to Fernando Verdasco.
Richard Gasquet was the defending champion but chose not to defend his title.
This was the first edition of the tournament.
Pablo Andújar was the defending champion and successfully defended his title.
This was the first edition of the tournament.
Tommy Robredo was the defending champion but retired in the first round against Maxime Janvier.
Hubert Hurkacz was the defending champion but lost in the semifinals to Rudolf Molleker.
Nikoloz Basilashvili was the defending champion and successfully defended his title, defeating Andrey Rublev in the final, 7–5, 4–6, 6–3. En route to doing so, Basilashvili saved two match points against Alexander Zverev in the semifinals.
Lorenzo Sonego was the defending champion and successfully defended his title, defeating Alejandro Davidovich Fokina 6–2, 4–6, 7–6(8–6) in the final.
Kimmer Coppejans was the defending champion but lost in the quarterfinals to Alejandro Davidovich Fokina.
Roberto Carballés Baena was the defending champion but retired in the third round against Jozef Kovalík.
Marco Cecchinato was the defending champion, but lost in the first round to Roberto Carballés Baena.
Roberto Carballés Baena was the defending champion but chose not to defend his title.
Roberto Carballés Baena and Alejandro Davidovich Fokina were the defending champions, but Davidovich Fokina chose to participate in Marseille instead. Carballés Baena partnered Federico Coria but lost in the first round to Raven Klaasen and Ben McLachlan.
Pedro Martínez was the defending champion but chose not to defend his title.
Albert Ramos Viñolas defeated Cameron Norrie in the final, 4–6, 6–3, 7–6(7–3) to win the singles tennis title at the 2021 Estoril Open. It marked his third career ATP Tour singles title, all of which have been on clay. Norrie was aiming to win his first ATP Tour title in his second final.
Rafael Nadal defeated the defending champion Novak Djokovic in the final, 7–5, 1–6, 6–3 to win the men's singles tennis title at the 2021 Italian Open. It was his record-extending 10th Italian Open title and record-equaling 36th Masters 1000 title overall. Nadal saved two match points en route to the title, in his third round match against Denis Shapovalov. This was also the fourth time that Nadal had won a tournament on 10 or more occasions, making him the only tennis player with the feat.
Daniil Medvedev defeated Sam Querrey in the final, 6–4, 6–2, to win the singles tennis title at the 2021 Mallorca Championships. It was Medvedev's first career grass court final and singles title on the ATP Tour, and he dropped just one set en route to the victory. Querrey was contesting for his first title in four years.
Roberto Carballés Baena was the defending champion but lost in the final to Tallon Griekspoor.
Pedro Martínez was the defending champion but lost in the first round to Kimmer Coppejans.