| Singles | |
|---|---|
| 2021 Moneta Czech Open | |
| Champion |  Federico Coria |
| Runner-up |  Alex Molčan |
| Score | 7–6(7–1), 6–3 |
Kamil Majchrzak was the defending champion [1] but chose not to defend his title.
Federico Coria won the title after defeating Alex Molčan 7–6(7–1), 6–3 in the final.
Pablo Andújar (first round)
Jiří Veselý (second round)
Gianluca Mager (semifinals) Federico Coria (champion)
Hugo Dellien (quarterfinals) Jozef Kovalík (first round) Juan Manuel Cerúndolo (first round, retired)
Blaž Rola (quarterfinals)| Semifinals | Final | ||||||||||||
| Alex Molčan | 6 | 6 | |||||||||||
| 3 | Gianluca Mager | 1 | 3 | ||||||||||
| Alex Molčan | 61 | 3 | |||||||||||
| 4 | Federico Coria | 77 | 6 | ||||||||||
| 4 | Federico Coria | 6 | 6 | ||||||||||
| Zdeněk Kolář | 4 | 2 | |||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | P Andújar | 6 | 1 | 4 | |||||||||||||||||||||||
 Yo Watanuki | 1 | 6 | 6 | Yo Watanuki | 1 | 2 | |||||||||||||||||||||
| A Molčan | 6 | 6 | A Molčan | 6 | 6 | ||||||||||||||||||||||
| Q | David Poljak | 3 | 3 | A Molčan | 6 | 6 | |||||||||||||||||||||
 G Oliveira | 3 | 6 | 4 | 5 | H Dellien | 3 | 1 | ||||||||||||||||||||
| M Vrbenský | 6 | 2 | 6 | M Vrbenský | 1 | 2 | |||||||||||||||||||||
| WC | A Paulson | 1 | 3 | 5 | H Dellien | 6 | 6 | ||||||||||||||||||||
| 5 | H Dellien | 6 | 6 | A Molčan | 6 | 6 | |||||||||||||||||||||
| 3 | G Mager | 6 | 6 | 3 | G Mager | 1 | 3 | ||||||||||||||||||||
| Alt | J Forejtek | 3 | 3 | 3 | G Mager | 710 | 6 | ||||||||||||||||||||
| WC | Daniel Siniakov | 1 | 0 | S Báez | 68 | 2 | |||||||||||||||||||||
| S Báez | 6 | 6 | 3 | G Mager | 6 | 6 | |||||||||||||||||||||
 M Bachinger | 6 | 0 | 1 | WC | D Svrčina | 3 | 2 | ||||||||||||||||||||
| WC | D Svrčina | 2 | 6 | 6 | WC | D Svrčina | 6 | 7 | |||||||||||||||||||
| Q |  A Erler | 77 | 4 | Q | A Erler | 1 | 5 | ||||||||||||||||||||
| 7 | JM Cerúndolo | 61 | 2r | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 8 | B Rola | 6 | 7 | ||||||||||||||||||||||||
| Q |  A Rybakov | 1 | 5 | 8 | B Rola | 6 | 3 | 78 | |||||||||||||||||||
| J Lehečka | 5 | 5 | L Klein | 4 | 6 | 66 | |||||||||||||||||||||
| L Klein | 7 | 7 | 8 | B Rola | 4 | 1 | |||||||||||||||||||||
| PR |  A Kuznetsov | 6 | 77 | 4 | F Coria | 6 | 6 | ||||||||||||||||||||
| LL |  J Sels | 0 | 64 | PR | A Kuznetsov | 77 | 5 | 2 | |||||||||||||||||||
| LL | J Härteis | 1 | 0 | 4 | F Coria | 60 | 7 | 6 | |||||||||||||||||||
| 4 | F Coria | 6 | 6 | 4 | F Coria | 6 | 6 | ||||||||||||||||||||
| 6 | J Kovalík | 6 | 64 | 4 | Z Kolář | 4 | 2 | ||||||||||||||||||||
| V Kopřiva | 2 | 77 | 6 | V Kopřiva | 3 | 63 | |||||||||||||||||||||
| L Miedler | 2 | 2 | Z Kolář | 6 | 77 | ||||||||||||||||||||||
| Z Kolář | 6 | 6 | Z Kolář | 6 | 6 | ||||||||||||||||||||||
| Q |  S Mansouri | 0 | 6 | 2 | T Kamke | 2 | 3 | ||||||||||||||||||||
| T Kamke | 6 | 3 | 6 | T Kamke | 6 | 6 | |||||||||||||||||||||
| F Mena | 2 | 65 | 2 | J Veselý | 3 | 4 | |||||||||||||||||||||
| 2 | J Veselý | 6 | 77 | ||||||||||||||||||||||||
Tommy Robredo was the defending champion but withdrew due to leg injury.
Horacio Zeballos defeated Rafael Nadal in the final, 6–7(2–7), 7–6(8–6), 6–4 to win the singles tennis title at the 2013 Chile Open. It was Nadal's first tournament in eight months.
Pablo Cuevas was the defending champion and successfully defended his title, defeating Pablo Carreño Busta in the final, 7–6(7–4), 6–3.
Jo-Wilfried Tsonga was the defending champion, but due to injury did not defend his title.
Pablo Andújar was the defending champion but chose not to defend his title.
Laslo Đere was the defending champion, but withdrew with an abdominal injury before the tournament began.
Alexander Bublik was the defending champion but chose not to defend his title.
Pablo Andújar was the defending champion but lost in the final to Kamil Majchrzak.
This was the first edition of the tournament, primarily organised due to the cancellation of many tournaments in 2020, due to the COVID-19 pandemic.
Andy Murray was the defending champion, but this year he decided to participate in the Cologne event instead, where he later withdrew due to hip injury.
Pablo Andújar was the defending champion but chose not to defend his title.
Cristian Garín defeated Facundo Bagnis in the final, 6–4, 6–7(3–7), 7–5 to capture the men's singles tennis title at the 2021 Chile Open.
Roberto Carballés Baena and Alejandro Davidovich Fokina were the defending champions, but Davidovich Fokina chose to participate in Marseille instead. Carballés Baena partnered Federico Coria but lost in the first round to Raven Klaasen and Ben McLachlan.
Hugo Dellien was the defending champion but chose not to defend his title.
Pedro Martínez defeated Sebastián Báez in the final, 4–6, 6–4, 6–4 to win the singles title at the 2022 Chile Open. It was his first ATP Tour title.
Federico Coria was the defending champion but lost in the first round to Dalibor Svrčina.
Pablo Cuevas was the defending champion but chose not to defend his title.
Gian Marco Moroni was the defending champion but withdrew from the tournament due to a back injury.
Francisco Cerúndolo defeated Sebastián Báez in the final, 7–6(7–4), 6–2 to win the men's singles tennis title at the 2022 Swedish Open. It was his maiden ATP Tour title.
Zdeněk Kolář was the defending champion but chose not to defend his title.