| Singles | |
|---|---|
| 2021 Orlando Open | |
| Champion |  Jenson Brooksby |
| Runner-up | Denis Kudla |
| Score | 6–3, 6–3 |
Brandon Nakashima was the defending champion [1] but chose not to defend his title.
Jenson Brooksby won the title after defeating Denis Kudla 6–3, 6–3 in the final.
Steve Johnson (first round)
Yasutaka Uchiyama (second round) Mackenzie McDonald (first round)
Thiago Seyboth Wild (second round) Denis Kudla (final)
Prajnesh Gunneswaran (second round)
Jason Jung (first round)
Alejandro Tabilo (first round)| Semifinals | Final | ||||||||||||
| 5 | Denis Kudla | 2 | 6 | 6 | |||||||||
 Roberto Cid Subervi | 6 | 2 | 2 | ||||||||||
| 5 | Denis Kudla | 3 | 3 | ||||||||||
| Jenson Brooksby | 6 | 6 | |||||||||||
| WC | Christian Harrison | 5 | 1 | ||||||||||
| Jenson Brooksby | 7 | 6 | |||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | S Johnson | 1 | 63 | ||||||||||||||||||||||||
| C Eubanks | 6 | 77 | C Eubanks | 6 | 3 | 2 | |||||||||||||||||||||
| M Mmoh | 6 | 4 | 6 | M Mmoh | 3 | 6 | 6 | ||||||||||||||||||||
| Q | M Damm | 4 | 6 | 1 | M Mmoh | 5 | 3 | ||||||||||||||||||||
| M Krueger | 3 | 4 | 5 | D Kudla | 7 | 6 | |||||||||||||||||||||
| Q |  T van Rijthoven | 6 | 6 | Q | T van Rijthoven | 7 | 2 | 5 | |||||||||||||||||||
| J Menezes | 2 | 2 | 5 | D Kudla | 5 | 6 | 7 | ||||||||||||||||||||
| 5 | D Kudla | 6 | 6 | 5 | D Kudla | 2 | 6 | 6 | |||||||||||||||||||
| 4 | T Seyboth Wild | 6 | 6 | R Cid Subervi | 6 | 2 | 2 | ||||||||||||||||||||
 F Mena | 2 | 0 | 4 | T Seyboth Wild | 62 | 2 | |||||||||||||||||||||
 M Torpegaard | 62 | 3 | R Cid Subervi | 77 | 6 | ||||||||||||||||||||||
| R Cid Subervi | 77 | 6 | R Cid Subervi | 3 | 6 | 4 | |||||||||||||||||||||
 E Gómez | 6 | 4 | 1 |  B Schnur | 6 | 2 | 0r | ||||||||||||||||||||
| B Fratangelo | 3 | 6 | 6 | B Fratangelo | 3 | 62 | |||||||||||||||||||||
| B Schnur | 6 | 6 | B Schnur | 6 | 77 | ||||||||||||||||||||||
| 8 | A Tabilo | 2 | 2 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 6 | P Gunneswaran | 6 | 6 | ||||||||||||||||||||||||
 M Ebden | 4 | 1 | 6 | P Gunneswaran | 3 | 4 | |||||||||||||||||||||
| Yo Watanuki | 1 | 1 | J Sock | 6 | 6 | ||||||||||||||||||||||
| J Sock | 6 | 6 | J Sock | 63 | 3 | ||||||||||||||||||||||
| WC | A Kovacevic | 6 | 5 | 6 | WC | C Harrison | 77 | 6 | |||||||||||||||||||
| Q | R Quiroz | 1 | 7 | 4 | WC | A Kovacevic | 4 | 3 | |||||||||||||||||||
| WC | C Harrison | 7 | 6 | WC | C Harrison | 6 | 6 | ||||||||||||||||||||
| 3 | M McDonald | 5 | 3 | WC | C Harrison | 5 | 1 | ||||||||||||||||||||
| 7 | J Jung | 1 | 4 | J Brooksby | 7 | 6 | |||||||||||||||||||||
| J Brooksby | 6 | 6 | J Brooksby | 6 | 6 | ||||||||||||||||||||||
| T-S Kwiatkowski | 2 | 3 | Q |  A Çelikbilek | 3 | 1 | |||||||||||||||||||||
| Q | A Çelikbilek | 6 | 6 | J Brooksby | 6 | 6 | |||||||||||||||||||||
| WC | Z Khan | 6 | 1 | 6 | WC | Z Khan | 4 | 3 | |||||||||||||||||||
| LL | K King | 3 | 6 | 1 | WC | Z Khan | 77 | 77 | |||||||||||||||||||
| P Polansky | 3 | 6 | 4 | 2 | Y Uchiyama | 65 | 65 | ||||||||||||||||||||
| 2 | Y Uchiyama | 6 | 3 | 6 | |||||||||||||||||||||||
Juan Martín del Potro was the defending champion and successfully defended his title, defeating Roger Federer in the final, 7–6(7–3), 2–6, 6–4.
Kei Nishikori was the defending champion and successfully defended his title, defeating Ivo Karlović in the final, 6–4, 7–6(7–0).
Kei Nishikori was the two-time defending champion and successfully defended his title, defeating Kevin Anderson 6–4, 6–4 in the final.
John Isner was the two-time defending champion, and he won the title for the third straight year, defeating Marcos Baghdatis in the final, 6–3, 6–3.
Defending champion Roger Federer defeated Rafael Nadal in the final, 6–3, 5–7, 6–3 to win the singles tennis title at the 2015 Swiss Indoors. This was Federer's tenth consecutive final at the event.
Novak Djokovic defeated the defending champion Andy Murray in the final, 6–2, 3–6, 6–3, to win the men's singles tennis title at the 2016 Madrid Open. It was Djokovic's second title in Madrid and his record 29th ATP Masters 1000 title.
Steve Johnson was the defending champion and successfully defended his title, defeating Tennys Sandgren in the final, 7–6(7–2), 2–6, 6–4.
Lucas Pouille was the defending champion, but lost in the semifinals to Milos Raonic.
Lucas Pouille was the defending champion, but lost to Borna Ćorić in the second round.
Mischa Zverev was the defending champion, but chose not to participate this year.
Michael Mmoh was the defending champion but lost in the second round to Brandon Nakashima.
Andreas Seppi was the defending champion but chose not to defend his title.
Marcos Giron was the defending champion but chose not to defend his title.
This event was the second edition of the Open Quimper Bretagne in 2021 after the Open d'Orléans was delayed due to the COVID-19 pandemic in France.
Roman Safiullin was the defending champion but chose not to defend his title.
Alexander Zverev defeated top seed Stefanos Tsitsipas in the final, 6–4, 7–6(7–3) to win the men's singles tennis title at the 2021 Mexican Open.
Aslan Karatsev defeated Andy Murray in the final, 6–3, 6–3 to win the men's singles title at the 2022 Sydney Tennis Classic. This was Murray's first ATP final since he won the 2019 European Open.
Dan Evans was the defending champion but chose not to defend his title.
Defending champion Matteo Berrettini defeated Filip Krajinović in the final, 7–5, 6–4 to win the singles tennis title at the 2022 Queen's Club Championships and successfully defend his title. By winning his fourth title on grass and seventh career ATP Tour singles title overall, Berrettini became the first player in the Open Era to claim the title in their first two appearances at the tournament. Krajinović had never earned a tour-level win on grass before the tournament and was contesting for his first career title in his fifth final.
J. J. Wolf was the defending champion but chose not to defend his title.