| Doubles | |
|---|---|
| 2021 Puerto Vallarta Open | |
| Champions |  Gijs Brouwer  Reese Stalder |
| Runners-up |  Hans Hach Verdugo Miguel Ángel Reyes-Varela |
| Score | 6–4, 6–4 |
Matt Reid and John-Patrick Smith were the defending champions [1] but chose not to defend their title.
Gijs Brouwer and Reese Stalder won the title after defeating Hans Hach Verdugo and Miguel Ángel Reyes-Varela 6–4, 6–4 in the final.
Hans Hach Verdugo / Miguel Ángel Reyes-Varela (final) Evan King / Hunter Reese (quarterfinals) Christian Harrison / Dennis Novikov (quarterfinals)
Adrián Menéndez Maceiras / Roberto Ortega Olmedo (semifinals)| First round | Quarterfinals | Semifinals | Final | ||||||||||||||||||||||||
| 1 | H Hach Verdugo MÁ Reyes-Varela | 6 | 6 | ||||||||||||||||||||||||
| WC | Milledge Cossu P Cuevas | 4 | 0 | 1 | H Hach Verdugo MÁ Reyes-Varela | 6 | 6 | ||||||||||||||||||||
A Kovacevic  R Roelofse | 67 | 65 | L Patiño  K Uchida | 2 | 4 | ||||||||||||||||||||||
| L Patiño K Uchida | 79 | 77 | 1 | H Hach Verdugo MÁ Reyes-Varela | 7 | 6 | |||||||||||||||||||||
| 4 | A Menéndez Maceiras R Ortega Olmedo | 3 | 6 | [10] | 4 | A Menéndez Maceiras R Ortega Olmedo | 5 | 1 | |||||||||||||||||||
| WC |  JS Gómez A Hernández | 6 | 2 | [2] | 4 | A Menéndez Maceiras R Ortega Olmedo | 77 | 1 | [10] | ||||||||||||||||||
M Cuevas  MF Descotte | 5 | 2 | S González G López Villaseñor | 63 | 6 | [5] | |||||||||||||||||||||
| S González G López Villaseñor | 7 | 6 | 1 | H Hach Verdugo MÁ Reyes-Varela | 4 | 4 | |||||||||||||||||||||
| G Nanda Mi Redlicki | 77 | 4 | [6] | G Brouwer R Stalder | 6 | 6 | |||||||||||||||||||||
| G Brouwer R Stalder | 62 | 6 | [10] | G Brouwer R Stalder | 6 | 6 | |||||||||||||||||||||
| PR | Pedro Vives Marcos T-l Wu | 64 | 4 | 3 | C Harrison D Novikov | 3 | 4 | ||||||||||||||||||||
| 3 | C Harrison D Novikov | 77 | 6 | G Brouwer R Stalder | 6 | 6 | |||||||||||||||||||||
 L Draxl A Galarneau | 6 | 6 | L Draxl A Galarneau | 4 | 4 | ||||||||||||||||||||||
| PR |  P Krstin  R Statham | 1 | 2 | L Draxl A Galarneau | 6 | 3 | [10] | ||||||||||||||||||||
| WC | Miguel Damas Samuel Sánchez | 2 | 2 | 2 | E King H Reese | 3 | 6 | [2] | |||||||||||||||||||
| 2 | E King H Reese | 6 | 6 | ||||||||||||||||||||||||
Johan Brunström and Frederik Nielsen won the title, defeating Sekou Bangoura and Matt Seeberger in the final 6–1, 6–2.
David O'Hare and Joe Salisbury won the title, defeating Austin Krajicek and Nicholas Monroe in the final 6–1, 6–4.
Marcelo Arévalo and Sergio Galdós were the defending champions but chose to defend their title with different partners. Arévalo partnered Miguel Ángel Reyes-Varela and successfully defended his title. Galdós partnered Roberto Maytín but lost in the first round to Arévalo and Reyes-Varela.
Philip Bester and Peter Polansky were the defending champions but chose not to defend their title.
Marcelo Arévalo and Miguel Ángel Reyes-Varela were the defending champions and successfully defended their title, defeating Ariel Behar and Roberto Quiroz 1–6, 6–4, [12–10] in the final.
Gonzalo Escobar and Manuel Sánchez were the defending champions but only Escobar chose to defend his title, partnering Luis David Martínez. Escobar lost in the first round to Adrián Menéndez Maceiras and Federico Zeballos.
Ante Pavić and Danilo Petrović were the defending champions but chose to defend their title with different partners. Pavić partnered Hans Hach Verdugo but lost in the quarterfinals to Gonzalo Escobar and Luis David Martínez. Petrović partnered Alex Hernández but lost in the quarterfinals to Matt Reid and John-Patrick Smith.
Marcelo Arévalo and Miguel Ángel Reyes-Varela were the defending champions, but lost in the first round to Hans Hach Verdugo and Dennis Novikov.
Marcos Giron and Dennis Novikov were the defending champions but only Novikov chose to defend his title, partnering Gonçalo Oliveira.
André Göransson and Marc-Andrea Hüsler were the defending champions but chose not to defend their title.
Sadio Doumbia and Fabien Reboul were the defending champions but chose not to defend their title.
Sekou Bangoura and Michael Mmoh were the defending champions but chose not to defend their title.
Romain Arneodo and Andrei Vasilevski were the defending champions but chose not to defend their title.
This was the first edition of the tournament.
André Göransson and Sem Verbeek were the defending champions but chose not to defend their title.
Diego Hidalgo and Nicolás Jarry were the defending champions but only Hidalgo chose to defend his title, partnering Sergio Galdós. Hidalgo lost in the quarterfinals to Hans Hach Verdugo and Miguel Ángel Reyes-Varela.
Ruben Gonzales and Ruan Roelofse were the defending champions but chose to defend their title with different partners. Gonzales partnered Hunter Johnson but lost in the first round to Hans Hach Verdugo and Miguel Ángel Reyes-Varela. Roelofse partnered Christopher Rungkat but lost in the quarterfinals to William Blumberg and Max Schnur.
Mitchell Krueger and Blaž Rola were the defending champions but lost in the first round to William Blumberg and Max Schnur.
Hans Hach Verdugo and Adrián Menéndez Maceiras were the defending champions but only Hach Verdugo chose to defend his title, partnering Miguel Ángel Reyes-Varela. Hach Verdugo lost in the final to Malek Jaziri and Blaž Rola.
Hans Hach Verdugo and Austin Krajicek were the defending champions but only Hach Verdugo chose to defend his title, partnering Miguel Ángel Reyes-Varela. Hach Verdugo lost in the semifinals to André Göransson and Ben McLachlan.