| Doubles | |
|---|---|
| 2021 Rancho Santa Fe Open | |
| Champions |  Katarzyna Kawa  Tereza Mihalíková |
| Runners-up |  Liang En-shuo  Rebecca Marino |
| Final score | 6–3, 4–6, [10–6] |
Kayla Day and Sophia Whittle were the defending champions [1] but chose not to participate.
Katarzyna Kawa and Tereza Mihalíková won the title, defeating Liang En-shuo and Rebecca Marino in the final, 6–3, 4–6, [10–6].
Katarzyna Kawa / Tereza Mihalíková (Champions) Liang En-shuo / Rebecca Marino (Final)
Conny Perrin / 
Renata Zarazúa (Quarterfinals)
Madison Brengle / 
Maddison Inglis (Semifinals)| First Round | Quarterfinals | Semifinals | Final | ||||||||||||||||||||||||
| 1 | K Kawa T Mihalíková | 6 | 6 | ||||||||||||||||||||||||
| A Broomfield H Verner | 4 | 1 | 1 | K Kawa T Mihalíková | 6 | 6 | |||||||||||||||||||||
T Arnold  B Thamchaiwat | 6 | 4 | [9] | L Küng A Osborne | 3 | 2 | |||||||||||||||||||||
| L Küng A Osborne | 3 | 6 | [11] | 1 | K Kawa T Mihalíková | 6 | 6 | ||||||||||||||||||||
| 4 | M Brengle M Inglis | 6 | 6 | 4 | M Brengle M Inglis | 3 | 4 | ||||||||||||||||||||
 L Pulchartová  R Ushijima | 3 | 2 | 4 | M Brengle M Inglis | 6 | 6 | |||||||||||||||||||||
 F Ferro E Jacquemot | E Kalieva A Krueger | 3 | 0 | ||||||||||||||||||||||||
| E Kalieva A Krueger | w/o | 1 | K Kawa T Mihalíková | 6 | 4 | [10] | |||||||||||||||||||||
| A Kulikov R Valdes | 2 | 7 | [10] | 2 | E-s Liang R Marino | 3 | 6 | [6] | |||||||||||||||||||
| J Aney H Chang | 6 | 5 | [6] | A Kulikov R Valdes | 6 | 3 | [10] | ||||||||||||||||||||
| L Cabrera P Hon | 77 | 66 | [5] | 3 | C Perrin R Zarazúa | 3 | 6 | [8] | |||||||||||||||||||
| 3 | C Perrin R Zarazúa | 65 | 78 | [10] | A Kulikov R Valdes | 6 | 5 | [8] | |||||||||||||||||||
| WC | S Colling E Goldsmith | 2 | 7 | [10] | 2 | E-s Liang R Marino | 0 | 7 | [10] | ||||||||||||||||||
| H Giavara D Hewitt | 6 | 5 | [8] | WC | S Colling E Goldsmith | 65 | 1 | ||||||||||||||||||||
| E Oosterhout M Partaud | 2 | 4 | 2 | E-s Liang R Marino | 77 | 6 | |||||||||||||||||||||
| 2 | E-s Liang R Marino | 6 | 6 | ||||||||||||||||||||||||
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