| Doubles | |
|---|---|
| 2022 Cali Open | |
| Champions |  Malek Jaziri  Adrián Menéndez Maceiras |
| Runners-up |  Keegan Smith Evan Zhu |
| Final score | 7–5, 6–4 |
This was the first edition of the tournament. The tournament originated as a quick replacement for the 2022 edition of the Quito Challenger, which was moved to Cali due to political unrest in Quito. [1]
Malek Jaziri and Adrián Menéndez Maceiras won the title after defeating Keegan Smith and Evan Zhu 7–5, 6–4 in the final.
Sriram Balaji / Jeevan Nedunchezhiyan (semifinals)
Chung Yun-seong / 
Michail Pervolarakis (first round) Carlos Gómez-Herrera / 
Roberto Quiroz (withdrew)
Mateus Alves / 
Nicolás Mejía (first round)
Viktor Durasovic / 
Gonçalo Oliveira (semifinals)| First round | Quarterfinals | Semifinals | Final | ||||||||||||||||||||||||
| 1 | S Balaji J Nedunchezhiyan | w/o | |||||||||||||||||||||||||
 P Krstin M Zekić | 1 | S Balaji J Nedunchezhiyan | 7 | 4 | |||||||||||||||||||||||
| Alt |  N Nakagawa Kosuke Ogura | 63 | 5 |  I Carou  F Mena | 5 | 2r | |||||||||||||||||||||
| I Carou F Mena | 77 | 7 | 1 | S Balaji J Nedunchezhiyan | 4 | 6 | [6] | ||||||||||||||||||||
| 4 | M Alves N Mejía | 64 | 3 | Alt | K Smith E Zhu | 6 | 1 | [10] | |||||||||||||||||||
| Alt | K Smith E Zhu | 77 | 6 | Alt | K Smith E Zhu | w/o | |||||||||||||||||||||
| JP Ficovich Matías Zukas | 6 | 5 | [10] | JP Ficovich M Zukas | |||||||||||||||||||||||
| Alt |  Blu Baker K Pannu | 4 | 7 | [6] | Alt | K Smith E Zhu | 5 | 4 | |||||||||||||||||||
| Facundo Juárez G Villanueva | 7 | 65 | [7] | M Jaziri A Menéndez Maceiras | 7 | 6 | |||||||||||||||||||||
| Alt | A Kovacevic Fernando Yamacita | 5 | 77 | [10] | Alt | A Kovacevic F Yamacita | 4 | 4 | |||||||||||||||||||
| Alt | Ignacio Monzón Juan Bautista Otegui | 1 | 4 | 5 | V Durasovic G Oliveira | 6 | 6 | ||||||||||||||||||||
| 5 | V Durasovic G Oliveira | 6 | 6 | 5 | V Durasovic G Oliveira | 3 | 2 | ||||||||||||||||||||
| F Meligeni Alves J Menezes | M Jaziri A Menéndez Maceiras | 6 | 6 | ||||||||||||||||||||||||
| WC | Mateo Gómez A Urrea | w/o | WC | M Gómez A Urrea | 3 | 66 | |||||||||||||||||||||
| M Jaziri A Menéndez Maceiras | 1 | 6 | [10] | M Jaziri A Menéndez Maceiras | 6 | 78 | |||||||||||||||||||||
| 2 | Y-s Chung M Pervolarakis | 6 | 4 | [8] | |||||||||||||||||||||||
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