| Singles | |
|---|---|
| 2022 Henderson Tennis Open | |
| Champion |  Yuan Yue |
| Runner-up |  Diana Shnaider |
| Score | 4–6, 6–3, 6–1 |
Emina Bektas was the defending champion [1] but chose not to participate.
Yuan Yue won the title, defeating Diana Shnaider in the final, 4–6, 6–3, 6–1.
Panna Udvardy (second round) Yuan Yue (champion)
Rebecca Peterson (semifinals)
Katie Volynets (quarterfinals) Asia Muhammad (first round) Katrina Scott (first round)
Astra Sharma (quarterfinals)
Nadia Podoroska (first round)| Semifinals | Final | ||||||||||||
| Diana Shnaider | 2 | 7 | 6 | ||||||||||
 Marcela Zacarías | 6 | 5 | 1 | ||||||||||
| Diana Shnaider | 6 | 3 | 1 | ||||||||||
| 2 | Yuan Yue | 4 | 6 | 6 | |||||||||
| 3 | Rebecca Peterson | 3 | 64 | ||||||||||
| 2 | Yuan Yue | 6 | 77 | ||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | P Udvardy | 6 | 6 | ||||||||||||||||||||||||
| WC | R Kingsley | 4 | 4 | 1 | P Udvardy | 4 | 4 | ||||||||||||||||||||
| D Shnaider | 6 | 6 | D Shnaider | 6 | 6 | ||||||||||||||||||||||
| Q |  C-y Hsu | 4 | 0 | D Shnaider | 6 | 7 | |||||||||||||||||||||
| Q | S Colling | 6 | 6 |  E Chong | 1 | 5 | |||||||||||||||||||||
 Y Naito | 3 | 4 | Q | S Colling | 5 | 0 | |||||||||||||||||||||
| E Chong | 7 | 6 | E Chong | 7 | 6 | ||||||||||||||||||||||
| 5 | A Muhammad | 5 | 2 | D Shnaider | 2 | 7 | 6 | ||||||||||||||||||||
| 4 | K Volynets | 6 | 4 | 6 | M Zacarías | 6 | 5 | 1 | |||||||||||||||||||
| WC | R McAdoo | 3 | 6 | 2 | 4 | K Volynets | 3 | 6 | 710 | ||||||||||||||||||
| A Glatch | 6 | 6 | A Glatch | 6 | 3 | 68 | |||||||||||||||||||||
| Q | C Corley | 3 | 4 | 4 | K Volynets | 5 | 4 | ||||||||||||||||||||
| Q | V Miroshnichenko | 6 | 2 | 2 | M Zacarías | 7 | 6 | ||||||||||||||||||||
| A Reami | 2 | 6 | 6 | A Reami | 1 | 4 | |||||||||||||||||||||
| M Zacarías | 6 | 77 | M Zacarías | 6 | 6 | ||||||||||||||||||||||
| 6 | K Scott | 2 | 65 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 7 | A Sharma | 6 | 6 | ||||||||||||||||||||||||
| Q |  K Kozarov | 0 | 2 | 7 | A Sharma | 61 | 6 | 6 | |||||||||||||||||||
| H Sakatsume | 6 | 6 | H Sakatsume | 77 | 4 | 2 | |||||||||||||||||||||
| Q | T Kinard | 1 | 2 | 7 | A Sharma | 64 | 5 | ||||||||||||||||||||
| D Hewitt | 4 | 4 | 3 | R Peterson | 77 | 7 | |||||||||||||||||||||
| A Lahey | 6 | 6 | A Lahey | 65 | 1 | ||||||||||||||||||||||
| WC | A Rogers | 4 | 0 | 3 | R Peterson | 77 | 6 | ||||||||||||||||||||
| 3 | R Peterson | 6 | 6 | 3 | R Peterson | 3 | 64 | ||||||||||||||||||||
| 8 | N Podoroska | 63 | 2 | 2 | Y Yuan | 6 | 77 | ||||||||||||||||||||
| WC |  Y Wickmayer | 77 | 6 | WC | Y Wickmayer | 6 | 6 | ||||||||||||||||||||
| Q | L Zaar | 1 | 65 | S Chang | 2 | 2 | |||||||||||||||||||||
| S Chang | 6 | 77 | WC | Y Wickmayer | 2 | 2 | |||||||||||||||||||||
| A Isaeva | 1 | 6 | 6 | 2 | Y Yuan | 6 | 6 | ||||||||||||||||||||
 K Volodko | 6 | 4 | 3 | A Isaeva | 2 | 3 | |||||||||||||||||||||
| Q |  A Sutjiadi | 0 | 2 | 2 | Y Yuan | 6 | 6 | ||||||||||||||||||||
| 2 | Y Yuan | 6 | 6 | ||||||||||||||||||||||||
Marie Bouzková was the defending champion, but she chose not to participate. Dalma Gálfi won the title, defeating Sofia Kenin in the final, 7–5, 6–4.
Wang Xinyu and You Xiaodi were the defending champions, but Wang chose to compete at the 2019 US Open instead. You partnered alongside Chihiro Muramatsu, but lost in the first round to Eudice Chong and Aldila Sutjiadi.
This was the first edition of the tournament.
Simona Halep was the defending champion, but chose not to participate.
This was the first edition of this tennis tournament.
Katie Swan was the defending champion but chose not to participate.
Sloane Stephens defeated Marie Bouzková in the final, 7–5, 1–6, 6–2, to win the singles title at the 2022 Abierto Zapopan. It marked the first final and title for Stephens since 2018.
Anastasia Potapova defeated Veronika Kudermetova in the final, 6–3, 6–1 to win the singles title at the 2022 İstanbul Cup. It was her maiden WTA Tour title.
Jule Niemeier was the defending champion but chose not to participate.
Clara Burel was the defending champion but chose to participate at the 2022 Karlsruhe Open instead.
Jasmine Paolini was the defending champion but chose not to participate.
Daniela Vismane was the defending champion but retired in her first round match against Klaudija Bubelytė.
Marie Bouzková defeated Anastasia Potapova in the final, 6–0, 6–3 to win the singles tennis title at the 2022 Prague Open. It was her maiden WTA Tour title.
Liudmila Samsonova defeated Kaia Kanepi in the final, 4–6, 6–3, 6–3 to win the women's singles tennis title at the 2022 Washington Open. Kanepi was aiming to win her first title since 2013, and to be the oldest player to win a WTA Tour title since Serena Williams in 2020.
Nuria Párrizas Díaz was the defending champion but chose to compete at the 2022 National Bank Open instead.
Shelby Rogers was the defending champion but chose not to participate.
Rebecca Peterson was the defending champion but withdrew before her first round match.
Misaki Doi was the defending champion but chose to compete at the 2022 Torneig Internacional Els Gorchs instead.
Madison Brengle was the defending champion, but lost in the second round to Sofia Kenin.
Zhu Lin is the reigning champion from when the tournament was last held in 2019, but chose not to compete this year.