| Singles | |
|---|---|
| 2022 Morelos Open | |
| Champion |  Jay Clarke |
| Runner-up |  Adrián Menéndez Maceiras |
| Score | 6–1, 4–6, 7–6(7–5) |
Jurij Rodionov was the defending champion [1] but chose not to defend his title.
Jay Clarke won the title after defeating Adrián Menéndez Maceiras 6–1, 4–6, 7–6(7–5) in the final.
Ernesto Escobedo (quarterfinals)
Tim van Rijthoven (first round) Jay Clarke (champion)
Juan Pablo Ficovich (first round)
Brayden Schnur (first round, retired)
Nicolás Mejía (second round)
Yūichi Sugita (first round, retired)
Rinky Hijikata (semifinals)| Semifinals | Final | ||||||||||||
| Adrián Menéndez Maceiras | 1 | 6 | 6 | ||||||||||
 Chung Yun-seong | 6 | 1 | 4 | ||||||||||
| Adrián Menéndez Maceiras | 1 | 6 | 65 | ||||||||||
| 3 | Jay Clarke | 6 | 4 | 77 | |||||||||
| 3 | Jay Clarke | 6 | 7 | ||||||||||
| 8 | Rinky Hijikata | 2 | 5 | ||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | E Escobedo | 6 | 6 | ||||||||||||||||||||||||
 D Istomin | 4 | 4 | 1 | E Escobedo | 77 | 6 | |||||||||||||||||||||
 C Hemery | 610 | 6 | 3 |  P Gunneswaran | 62 | 4 | |||||||||||||||||||||
| P Gunneswaran | 712 | 4 | 6 | 1 | E Escobedo | 1 | 63 | ||||||||||||||||||||
| Q |  B Lock | 6 | 6 | A Menéndez Maceiras | 6 | 77 | |||||||||||||||||||||
 S Mansouri | 4 | 2 | Q | B Lock | 2 | 3 | |||||||||||||||||||||
| A Menéndez Maceiras | 5 | 77 | 2 | A Menéndez Maceiras | 6 | 6 | |||||||||||||||||||||
| 5 | B Schnur | 7 | 63 | 1r | A Menéndez Maceiras | 1 | 6 | 6 | |||||||||||||||||||
| 4 | JP Ficovich | 6 | 4 | 5 | Y-s Chung | 6 | 1 | 4 | |||||||||||||||||||
| A Kovacevic | 3 | 6 | 7 | A Kovacevic | 6 | 5 | 4 | ||||||||||||||||||||
| B Tomic | 3 | 6 | 4 | Y-s Chung | 3 | 7 | 6 | ||||||||||||||||||||
| Y-s Chung | 6 | 3 | 6 | Y-s Chung | 6 | 6 | |||||||||||||||||||||
| Q | K Smith | 6 | 6 | Q | K Smith | 1 | 4 | ||||||||||||||||||||
| Q |  F Sun | 4 | 2 | Q | K Smith | 7 | 6 | ||||||||||||||||||||
| WC |  A Hernández | 6 | 3 | WC | A Hernández | 5 | 4 | ||||||||||||||||||||
| 7 | Y Sugita | 3 | 1r | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 6 | N Mejía | 6 | 6 | ||||||||||||||||||||||||
 FC Jianu | 4 | 3 | 6 | N Mejía | 4 | 65 | |||||||||||||||||||||
| WC | Rodolfo Jauregui Sainz de Rozas | 2 | 2 |  R Quiroz | 6 | 77 | |||||||||||||||||||||
| R Quiroz | 6 | 6 | R Quiroz | 3 | 4 | ||||||||||||||||||||||
| Q |  Elmar Ejupovic | 6 | 0 | 3 | J Clarke | 6 | 6 | ||||||||||||||||||||
 G Oliveira | 3 | 0r | Q | E Ejupovic | 77 | 3 | 64 | ||||||||||||||||||||
 V Durasovic | 4 | 7 | 3 | 3 | J Clarke | 63 | 6 | 77 | |||||||||||||||||||
| 3 | J Clarke | 6 | 5 | 6 | 3 | J Clarke | 6 | 7 | |||||||||||||||||||
| 8 | R Hijikata | 6 | 6 | 8 | R Hijikata | 2 | 5 | ||||||||||||||||||||
| WC | R Pacheco Méndez | 3 | 2 | 8 | R Hijikata | 6 | 6 | ||||||||||||||||||||
| M Jaziri | 5 | 6 | 77 | M Jaziri | 0 | 2 | |||||||||||||||||||||
 P Krstin | 7 | 1 | 62 | 8 | R Hijikata | 6 | 6 | ||||||||||||||||||||
| Q | N Nakagawa | 2 | 1 | S Diez | 0 | 1 | |||||||||||||||||||||
| S Diez | 6 | 6 | S Diez | 77 | 6 | ||||||||||||||||||||||
| Q | S Mochizuki | 2 | 77 | 6 | Q | S Mochizuki | 62 | 3 | |||||||||||||||||||
| 2 | T van Rijthoven | 6 | 62 | 4 | |||||||||||||||||||||||
Kenneth Raisma and Stefanos Tsitsipas were the defending champions but both players were no longer eligible to participate in junior events.
Filip Krajinović was the defending champion but chose not to defend his title.
Novak Djokovic was the defending champion, but chose not to participate this year.
Egor Gerasimov was the defending champion but lost in the second round to Jurij Rodionov.
Cameron Norrie was the defending champion but chose not to defend his title.
Jurij Rodionov was the defending champion but chose not to defend his title.
Yannick Hanfmann was the defending champion but chose not to defend his title.
Jannik Sinner was the defending champion but chose not to defend his title.
Lorenzo Sonego defeated defending champion Laslo Đere in the final, 2–6, 7–6(7–5), 6–4 to win the men's singles title at the 2021 Sardegna Open. With the victory, Sonego became the first Italian in 15 years to capture an ATP Tour title on home soil.
Evgeny Donskoy was the defending champion but chose not to defend his title.
Jo-Wilfried Tsonga was the defending champion but chose not to defend his title.
John Millman was the defending champion, but lost in the quarterfinals to James Duckworth.
Jannik Sinner was the defending champion and successfully defended his title, defeating Gaël Monfils in the final, 6–3, 6–4.
João Sousa defeated Emil Ruusuvuori in the final, 7–6(11–9), 4–6, 6–1 to win the singles title at the 2022 Tata Open Maharashtra. Sousa saved three match points against Elias Ymer in the semifinals. This was his first title since 2018.
Cameron Norrie defeated Reilly Opelka in the final, 7–6(7–1), 7–6(7–4) to win the singles title at the 2022 Delray Beach Open.
Benjamin Bonzi was the defending champion but chose not to defend his title.
Matteo Berrettini defeated Andy Murray in the final, 6–4, 5–7, 6–3 to win the singles tennis title at the 2022 Stuttgart Open.
Andrey Kuznetsov was the defending champion but chose not to defend his title.
Lorenzo Sonego defeated Alexander Bublik in the final, 7–6(7–3), 6–2 to win the singles tennis title at the 2022 Moselle Open.
Jordan Thompson was the defending champion but chose not to defend his title.