| Singles | |
|---|---|
| 2022 Savannah Challenger | |
| Champion |  Jack Sock |
| Runner-up | Christian Harrison |
| Score | 6–4, 6–1 |
Federico Coria was the defending champion [1] but chose not to defend his title.
Jack Sock won the title after defeating Christian Harrison 6–4, 6–1 in the final.
Tomás Martín Etcheverry (quarterfinals) Stefan Kozlov (first round)
Emilio Gómez (first round, retired) Jack Sock (champion)
Tomás Barrios Vera (first round) J. J. Wolf (semifinals) Tennys Sandgren (first round) Bjorn Fratangelo (semifinals)| Semifinals | Final | ||||||||||||
| Christian Harrison | 6 | 6 | |||||||||||
| 6 | J. J. Wolf | 1 | 3 | ||||||||||
| Christian Harrison | 4 | 1 | |||||||||||
| 4 | Jack Sock | 6 | 6 | ||||||||||
| 4 | Jack Sock | 6 | 6 | ||||||||||
| 8 | Bjorn Fratangelo | 2 | 4 | ||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | TM Etcheverry | 6 | 6 | ||||||||||||||||||||||||
| Q | A Mayo | 4 | 1 | 1 | TM Etcheverry | 1 | 6 | 3 | |||||||||||||||||||
| Q |  A Fils | 4 | 6 | 6 | Q | A Fils | 6 | 3 | 0r | ||||||||||||||||||
 N Kuhn | 6 | 1 | 3 | 1 | TM Etcheverry | 4 | 2 | ||||||||||||||||||||
| C Harrison | 6 | 6 | C Harrison | 6 | 6 | ||||||||||||||||||||||
| Q | Ezekiel Clark | 1 | 3 | C Harrison | 6 | 6 | |||||||||||||||||||||
 A Galarneau | 6 | 6 | A Galarneau | 2 | 3 | ||||||||||||||||||||||
| 7 | T Sandgren | 3 | 1 | C Harrison | 6 | 6 | |||||||||||||||||||||
| 3 | E Gómez | 2 | 4r | 6 | J. J. Wolf | 1 | 3 | ||||||||||||||||||||
 J Jung | 6 | 4 | J Jung | 5 | 4 | ||||||||||||||||||||||
| A Rybakov | 6 | 6 | A Rybakov | 7 | 6 | ||||||||||||||||||||||
 K Uchida | 3 | 2 | A Rybakov | 3 | 4 | ||||||||||||||||||||||
| M Mmoh | 3 | 1r | 6 | J. J. Wolf | 6 | 6 | |||||||||||||||||||||
 J Kubler | 6 | 1 | J Kubler | 3 | 6 | 2 | |||||||||||||||||||||
 R Ramanathan | 64 | 0 | 6 | J. J. Wolf | 6 | 2 | 6 | ||||||||||||||||||||
| 6 | J. J. Wolf | 77 | 6 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 5 | T Barrios Vera | 2 | 6 | 65 | |||||||||||||||||||||||
| Q | G Nanda | 6 | 3 | 77 | Q | G Nanda | 4 | 3 | |||||||||||||||||||
| Q | S Kirchheimer | 5 | 3 |  Zh Zhang | 6 | 6 | |||||||||||||||||||||
| Zh Zhang | 7 | 6 | Zh Zhang | 4 | 6 | 3 | |||||||||||||||||||||
| T-l Wu | 2 | 5 | 4 | J Sock | 6 | 3 | 6 | ||||||||||||||||||||
| S Nagal | 6 | 7 | S Nagal | 3 | 3 | ||||||||||||||||||||||
 M Torpegaard | 3 | 77 | 4 | 4 | J Sock | 6 | 6 | ||||||||||||||||||||
| 4 | J Sock | 6 | 63 | 6 | 4 | J Sock | 6 | 6 | |||||||||||||||||||
| 8 | B Fratangelo | 6 | 6 | 8 | B Fratangelo | 2 | 4 | ||||||||||||||||||||
| Alt |  M Safwat | 0 | 0 | 8 | B Fratangelo | 77 | 6 | ||||||||||||||||||||
| WC | N Rubin | 2 | 1 |  G Brouwer | 65 | 3 | |||||||||||||||||||||
| G Brouwer | 6 | 6 | 8 | B Fratangelo | 6 | 4 | 77 | ||||||||||||||||||||
| WC | O Crawford | 6 | 6 | Q |  J Pereira | 2 | 6 | 63 | |||||||||||||||||||
| WC | L Tien | 3 | 1 | WC | O Crawford | 4 | 3 | ||||||||||||||||||||
| Q | J Pereira | 6 | 6 | Q | J Pereira | 6 | 6 | ||||||||||||||||||||
| 2 | S Kozlov | 1 | 0 | ||||||||||||||||||||||||
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