| Singles | |
|---|---|
| 2022 Sibiu Open | |
| Champion |  Nerman Fatić |
| Runner-up | Damir Džumhur |
| Score | 6–3, 6–4 |
Stefano Travaglia was the defending champion [1] but chose not to defend his title.
Nerman Fatić won the title after defeating Damir Džumhur 6–3, 6–4 in the final.
Federico Coria (semifinals)
Filip Misolic (quarterfinals)
Zdeněk Kolář (second round) Thiago Agustín Tirante (first round)
Riccardo Bonadio (first round) Damir Džumhur (final)
Kimmer Coppejans (first round)
Nikola Milojević (second round)| Semifinals | Final | ||||||||||||
| 1 | Federico Coria | 6 | 4 | 3 | |||||||||
| Nerman Fatić | 4 | 6 | 6 | ||||||||||
| Nerman Fatić | 6 | 6 | |||||||||||
| 6 | Damir Džumhur | 3 | 4 | ||||||||||
| 6 | Damir Džumhur | 0 | 78 | 6 | |||||||||
 Nicholas David Ionel | 6 | 66 | 3 | ||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | F Coria | 6 | 6 | ||||||||||||||||||||||||
 R Ramanathan | 2 | 1 | 1 | F Coria | 77 | 6 | |||||||||||||||||||||
| Q |  S Diez | 6 | 6 | Q | S Diez | 64 | 4 | ||||||||||||||||||||
| M Bašić | 1 | 3 | 1 | F Coria | 3 | ||||||||||||||||||||||
 M Valkusz | 77 | 77 | M Valkusz | 0r | |||||||||||||||||||||||
| WC | M Copil | 63 | 64 | M Valkusz | 6 | 6 | |||||||||||||||||||||
 L Van Assche | 5 | 6 | 2 | 8 | N Milojević | 1 | 2 | ||||||||||||||||||||
| 8 | N Milojević | 7 | 1 | 6 | 1 | F Coria | 6 | 4 | 3 | ||||||||||||||||||
| 4 | TA Tirante | 77 | 5 | 1 | N Fatić | 4 | 6 | 6 | |||||||||||||||||||
| Q |  I Gakhov | 65 | 7 | 6 | Q | I Gakhov | 6 | 6 | |||||||||||||||||||
 DN Mădăraș | 1 | 4 | Q | G Fonio | 4 | 2 | |||||||||||||||||||||
| Q | G Fonio | 6 | 6 | Q | I Gakhov | 4 | 0 | ||||||||||||||||||||
 L Wessels | 4 | 6 | 6 | N Fatić | 6 | 6 | |||||||||||||||||||||
| M Bellucci | 6 | 3 | 4 | L Wessels | 3 | 64 | |||||||||||||||||||||
| N Fatić | 6 | 6 | N Fatić | 6 | 77 | ||||||||||||||||||||||
| 5 | R Bonadio | 3 | 3 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 6 | D Džumhur | 6 | 6 | ||||||||||||||||||||||||
 F Horanský | 3 | 2 | 6 | D Džumhur | 6 | 6 | |||||||||||||||||||||
| Q | Kai Wehnelt | 4 | 5 |  J Nikles | 4 | 3 | |||||||||||||||||||||
| J Nikles | 6 | 7 | 6 | D Džumhur | 711 | 6 | |||||||||||||||||||||
| WC | VV Cornea | 2 | 5 | L Klein | 69 | 1 | |||||||||||||||||||||
| L Klein | 6 | 7 | L Klein | 7 | 6 | ||||||||||||||||||||||
| WC | D Dima | 2 | 3 | 3 | Z Kolář | 5 | 3 | ||||||||||||||||||||
| 3 | Z Kolář | 6 | 6 | 6 | D Džumhur | 0 | 78 | 6 | |||||||||||||||||||
| 7 | K Coppejans | 3 | 1 | ND Ionel | 6 | 66 | 3 | ||||||||||||||||||||
| ND Ionel | 6 | 6 | ND Ionel | 3 | 6 | 2 | |||||||||||||||||||||
| Q |  Georgii Kravchenko | 6 | 1 | 63 | FC Jianu | 6 | 4 | 0r | |||||||||||||||||||
| FC Jianu | 2 | 6 | 77 | ND Ionel | 6 | 6 | |||||||||||||||||||||
| Q | R Molleker | 6 | 6 | 2 | F Misolic | 2 | 3 | ||||||||||||||||||||
 B Harris | 4 | 2 | Q | R Molleker | 3 | 6 | 3 | ||||||||||||||||||||
| PR | J Choinski | 3 | 6 | 2 | 2 | F Misolic | 6 | 3 | 6 | ||||||||||||||||||
| 2 | F Misolic | 6 | 3 | 6 | |||||||||||||||||||||||
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