| Singles | |
|---|---|
| 2023 Matsuyama Challenger | |
| Champion |  Luca Nardi |
| Runner-up |  Taro Daniel |
| Score | 3–6, 6–4, 6–2 |
Hong Seong-chan was the defending champion [1] but lost in the first round to Luca Nardi.
Nardi won the title after defeating Taro Daniel 3–6, 6–4, 6–2 in the final.
Taro Daniel (final) Shintaro Mochizuki (second round) Luca Nardi (champion) Sho Shimabukuro (second round)
Benjamin Hassan (quarterfinals)
Marc Polmans (first round)
Bu Yunchaokete (quarterfinals)
Hsu Yu-hsiou (quarterfinals)| Semifinals | Final | ||||||||||||
| 1 | Taro Daniel | 77 | 6 | ||||||||||
| Q |  August Holmgren | 65 | 2 | ||||||||||
| 1 | Taro Daniel | 6 | 4 | 2 | |||||||||
| 3 | Luca Nardi | 3 | 6 | 6 | |||||||||
| 3 | Luca Nardi | 6 | 6 | ||||||||||
 Geoffrey Blancaneaux | 3 | 3 | |||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | T Daniel | 6 | 6 | ||||||||||||||||||||||||
| WC | Shunsuke Nakagawa | 1 | 2 | 1 | T Daniel | 6 | 3 | 6 | |||||||||||||||||||
 M Echargui | 6 | 6 | M Echargui | 2 | 6 | 2 | |||||||||||||||||||||
| A Weber | 0 | 3 | 1 | T Daniel | 6 | 3 | 7 | ||||||||||||||||||||
| J Jung | 4 | 6 | 4 | 8 | Y-h Hsu | 2 | 6 | 5 | |||||||||||||||||||
| Y Shimizu | 6 | 2 | 6 | Y Shimizu | 4 | 3 | |||||||||||||||||||||
 Z Kolář | 2 | 3 | 8 | Y-h Hsu | 6 | 6 | |||||||||||||||||||||
| 8 | Y-h Hsu | 6 | 6 | 1 | T Daniel | 77 | 6 | ||||||||||||||||||||
| 4 | S Shimabukuro | 5 | 6 | 6 | Q | A Holmgren | 65 | 2 | |||||||||||||||||||
| G Fonio | 7 | 4 | 4 | 4 | S Shimabukuro | 63 | 3 | ||||||||||||||||||||
 D Ajduković | 6 | 6 | D Ajduković | 77 | 6 | ||||||||||||||||||||||
| K Uchida | 4 | 4 | D Ajduković | 5 | 6 | 65 | |||||||||||||||||||||
| T-l Wu | 4 | 1 | Q | A Holmgren | 7 | 3 | 77 | ||||||||||||||||||||
| WC | Y Uchiyama | 6 | 6 | WC | Y Uchiyama | 68 | 65 | ||||||||||||||||||||
| Q | A Holmgren | 6 | 6 | Q | A Holmgren | 710 | 77 | ||||||||||||||||||||
| 6 | M Polmans | 0 | 4 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 7 | Y Bu | 64 | 6 | 6 | |||||||||||||||||||||||
 M Efstathiou | 77 | 2 | 2 | 7 | Y Bu | 6 | 5 | 7 | |||||||||||||||||||
| Q | Z Li | 6 | 4 | 4 | D Sweeny | 4 | 7 | 5 | |||||||||||||||||||
| D Sweeny | 2 | 6 | 6 | 7 | Y Bu | 5 | 3 | ||||||||||||||||||||
 F Ferreira Silva | 3 | 2 | 3 | L Nardi | 7 | 6 | |||||||||||||||||||||
| J McCabe | 6 | 6 | J McCabe | 4 | 4 | ||||||||||||||||||||||
 S-c Hong | 5 | 6 | 64 | 3 | L Nardi | 6 | 6 | ||||||||||||||||||||
| 3 | L Nardi | 7 | 3 | 77 | 3 | L Nardi | 6 | 6 | |||||||||||||||||||
| 5 | B Hassan | 6 | 6 | G Blancaneaux | 3 | 3 | |||||||||||||||||||||
| Q | H Moriya | 4 | 4 | 5 | B Hassan | 1 | 77 | 6 | |||||||||||||||||||
| Q | J Trotter | 4 | 3 | Q | B Ellis | 6 | 64 | 3 | |||||||||||||||||||
| Q | B Ellis | 6 | 6 | 5 | B Hassan | 3 | 2 | ||||||||||||||||||||
| WC | Sho Katayama | 0 | 4 | G Blancaneaux | 6 | 6 | |||||||||||||||||||||
| G Blancaneaux | 6 | 6 | G Blancaneaux | 7 | 6 | ||||||||||||||||||||||
| Q | N Nakagawa | 2 | 2 | 2 | S Mochizuki | 5 | 3 | ||||||||||||||||||||
| 2 | S Mochizuki | 6 | 6 | ||||||||||||||||||||||||
Stanislas Wawrinka was the defending champion, but withdrew before the event started.
Carlos Berlocq won the title, defeating Tomáš Berdych in the final, 0–6, 7–5, 6–1.
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Martin Kližan won the title, defeating Daniel Gimeno Traver in the final, 6–2, 6–2.
Leonardo Mayer was the defending champion, but chose not to participate this year.
David Ferrer was the defending champion, but lost in the quarterfinals to Dominic Thiem.
Filip Krajinović was the defending champion but lost in the quarterfinals to Paolo Lorenzi.
Saketh Myneni was the defending champion but lost in the second round to Taro Daniel.
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Roger Federer was the defending champion and successfully defended his title, defeating Marius Copil in the final, 7–6(7–5), 6–4.
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Daniil Medvedev was the defending champion, but chose not to defend his title.
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Lorenzo Sonego defeated Alexander Bublik in the final, 7–6(7–3), 6–2 to win the singles tennis title at the 2022 Moselle Open.
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