ATP6V1E2

ATP6V1E2
Identifiers
Aliases	ATP6V1E2 , ATP6E1, ATP6EL2, ATP6V1EL2, VMA4, ATPase H+ transporting V1 subunit E2
External IDs	OMIM: 617385 MGI: 1922165 HomoloGene: 41770 GeneCards: ATP6V1E2
Gene location (Human)
Chr.	Chromosome 2 (human)
End	46,542,577 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	87,255,325 bp
RNA expression pattern
	Top expressed in
	sperm; ; islet of Langerhans; ; monocyte; ; gastrocnemius muscle; ; cingulate gyrus; ; Right adrenal gland; ; prefrontal cortex; ; putamen; ; amygdala; ; caudate nucleus;
	Top expressed in
	seminiferous tubule; ; spermatid; ; submandibular gland; ; spermatocyte; ; mucosa of small intestine; ; medial ganglionic eminence; ; right ventricle; ; digastric muscle; ; triceps brachii muscle; ; thoracic diaphragm;
	More reference expression data
	n/a
Gene ontology
Molecular function	P-type proton-exporting transporter activity ; protein binding ; proton-transporting ATPase activity, rotational mechanism ;
Cellular component	cytosol ; acrosomal vesicle ; proton-transporting two-sector ATPase complex, catalytic domain ;
Biological process	insulin receptor signaling pathway ; ion transmembrane transport ; ion transport ; transferrin transport ; regulation of macroautophagy ; phagosome acidification ;
	Sources:Amigo / QuickGO
Orthologs
	90423
	74915
	ENSG00000250565
	ENSMUSG00000053375
	Q96A05
	Q9D593
	NM_080653 ; NM_001318063 ; NM_001371281 ; NM_001371282 ; NM_001371283 Contents References ; External links ; Further reading ;
	NM_029121
	NP_001304992 ; NP_001358210 ; NP_001358211 ; NP_001358212
	NP_083397
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 04, 2023

V-type proton ATPase subunit E 2 is an enzyme that in humans is encoded by the ATP6V1E2 gene.^[5]^[6]

Related Research Articles

V-type proton ATPase subunit B, kidney isoform is an enzyme that in humans is encoded by the ATP6V1B1 gene.

V-type proton ATPase subunit E 1 is an enzyme that in humans is encoded by the ATP6V1E1 gene.

The TCIRG1 gene encodes for the V-type proton ATPase (V-ATPase) 116 kDa subunit a isoform 3 enzyme.

V-type proton ATPase 16 kDa proteolipid subunit is an enzyme that in humans is encoded by the ATP6V0C gene.

V-type proton ATPase subunit B, brain isoform is an enzyme that in humans is encoded by the ATP6V1B2 gene.

The human gene ATP6AP1 encodes the S1 subunit of the enzyme V-type proton ATPase.

V-type proton ATPase 116 kDa subunit a isoform 4 is an enzyme that in humans is encoded by the ATP6V0A4 gene.

V-type proton ATPase subunit C 1 is an enzyme that in humans is encoded by the ATP6V1C1 gene.

V-type proton ATPase 116 kDa subunit a isoform 1 is an enzyme that in humans is encoded by the ATP6V0A1 gene.

V-type proton ATPase catalytic subunit A is an enzyme that in humans is encoded by the ATP6V1A gene.

V-type proton ATPase subunit d 1 is an enzyme that in humans is encoded by the ATP6V0D1 gene.

V-type proton ATPase subunit G 2 is an enzyme that in humans is encoded by the ATP6V1G2 gene.

V-type proton ATPase subunit H is an enzyme that in humans is encoded by the ATP6V1H gene.

V-type proton ATPase subunit G 1 is an enzyme that in humans is encoded by the ATP6V1G1 gene.

V-type proton ATPase subunit D is an enzyme that in humans is encoded by the ATP6V1D gene.

V-type proton ATPase subunit F is an enzyme that in humans is encoded by the ATP6V1F gene.

V-type proton ATPase subunit G 3 is an enzyme that in humans is encoded by the ATP6V1G3 gene.

V-type proton ATPase 21 kDa proteolipid subunit is an enzyme that in humans is encoded by the ATP6V0B gene.

V-type proton ATPase subunit e 1 is an enzyme that in humans is encoded by the ATP6V0E1 gene.

V-type proton ATPase 116 kDa subunit a isoform 2 also known as V-ATPase 116 kDa isoform a2 is an enzyme that in humans is encoded by the ATP6V0A2 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000250565 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000053375 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Imai-Senga Y, Sun-Wada GH, Wada Y, Futai M (May 2002). "A human gene, ATP6E1, encoding a testis-specific isoform of H(+)-ATPase subunit E". Gene. 289 (1–2): 7–12. doi:10.1016/S0378-1119(02)00542-5. PMID 12036578.
↑ "Entrez Gene: ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2".

External links

Human ATP6V1E2 genome location and ATP6V1E2 gene details page in the UCSC Genome Browser .

Nishi T, Forgac M (2002). "The vacuolar (H+)-ATPases--nature's most versatile proton pumps". Nat. Rev. Mol. Cell Biol. 3 (2): 94–103. doi:10.1038/nrm729. PMID 11836511. S2CID 21122465.
Kawasaki-Nishi S, Nishi T, Forgac M (2003). "Proton translocation driven by ATP hydrolysis in V-ATPases". FEBS Lett. 545 (1): 76–85. doi:10.1016/S0014-5793(03)00396-X. PMID 12788495. S2CID 10507213.
Morel N (2004). "Neurotransmitter release: the dark side of the vacuolar-H+ATPase". Biol. Cell. 95 (7): 453–7. doi: 10.1016/S0248-4900(03)00075-3 . PMID 14597263. S2CID 17519696.
Breton S, Wiederhold T, Marshansky V, et al. (2000). "The B1 subunit of the H+ATPase is a PDZ domain-binding protein. Colocalization with NHE-RF in renal B-intercalated cells". J. Biol. Chem. 275 (24): 18219–24. doi: 10.1074/jbc.M909857199 . PMID 10748165.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Smith AN, Lovering RC, Futai M, et al. (2003). "Revised nomenclature for mammalian vacuolar-type H+ -ATPase subunit genes". Mol. Cell. 12 (4): 801–3. doi: 10.1016/S1097-2765(03)00397-6 . PMID 14580332.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. Bibcode:2005Natur.434..724H. doi: 10.1038/nature03466 . PMID 15815621.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000250565 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000053375 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12036578-5] Imai-Senga Y, Sun-Wada GH, Wada Y, Futai M (May 2002). "A human gene, ATP6E1, encoding a testis-specific isoform of H(+)-ATPase subunit E". Gene. 289 (1–2): 7–12. doi:10.1016/S0378-1119(02)00542-5. PMID 12036578.

[entrez-6] "Entrez Gene: ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2".

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ATP6V1E2

Contents

Related Research Articles

References

External links

Further reading