Agathobacter rectalis

Agathobacter rectalis
Scientific classification
Domain:	Bacteria
Kingdom:	Bacillati
Phylum:	Bacillota
Class:	Clostridia
Order:	Eubacteriales
Family:	Lachnospiraceae
Genus:	Agathobacter
Species:	A. rectalis
Binomial name
Agathobacter rectalis Rosero et al. 2016 [1]
Type strain
ATCC 33656 [2]
Synonyms
Bacteroides rectalis, [2] Pseudobacterium rectale, [2] Roseburia rectale, [2] Eubacterium rectale [2]

Agathobacter rectalis is a gram-positive, butyrate-producing, anaerobic, rod-shaped and non-spore-forming bacterium from the genus of Agathobacter with a single flagellate which occur in the rumen content of sheep and cows. ^{[1] [2]}

It is suggested that Eubacterium rectale is a synonym of A. rectalis, ^[1] but this is not universally accepted. ^{[3] [4]}

Reduced numbers of Agathobacter rectalis in the gut may be a risk factor for Alzheimer's disease. ^[5]

References

1. Rosero, J. A.; Killer, J.; Sechovcová, H.; Mrázek, J.; Benada, O.; Fliegerová, K.; Havlík, J.; Kopečný, J. (2016). "Reclassification of Eubacterium rectale (Hauduroy et al. 1937) Prévot 1938 in a new genus Agathobacter gen. nov. as Agathobacter rectalis comb. nov., and description of Agathobacter ruminis sp. nov., isolated from the rumen contents of sheep and cows". International Journal of Systematic and Evolutionary Microbiology . 66 (2): 768–773. doi:10.1099/ijsem.0.000788.
2. 
   "[Eubacterium] rectale". www.uniprot.org.
3. Sheridan, P. O.; Duncan, S. H.; Walker, A. W.; Scott, K. P.; Louis, P.; Flint, H. J. (2016). "Objections to the proposed reclassification of Eubacterium rectale as Agathobacter rectalis". International Journal of Systematic and Evolutionary Microbiology. 66 (5): 2106–2106. doi:10.1099/ijsem.0.000969.
4. Zuo, G.; Hao, B. (2016). "Whole-genome-based phylogeny supports the objections against the reclassification of Eubacterium rectale to Agathobacter rectalis". International Journal of Systematic and Evolutionary Microbiology. 66 (6): 2451–2451. doi:10.1099/ijsem.0.001047.
5. Lv, Xinhuang; Zhan, Lu; Ye, Tao; Xie, Huijia; Chen, Zhibo; Lin, Yan; Cai, Xianlei; Yang, Wenwen; Liao, Xiaolan; Liu, Jiaming; Sun, Jing (2024). "Gut commensal Agathobacter rectalis alleviates microglia-mediated neuroinflammation against pathogenesis of Alzheimer disease". iScience . 27 (11) 111116. doi:10.1016/j.isci.2024.111116. PMC   11532950 .