Cystic fibrosis (CF) is a genetic disorder inherited in an autosomal recessive manner that impairs the normal clearance of mucus from the lungs, which facilitates the colonization and infection of the lungs by bacteria, notably Staphylococcus aureus. CF is a rare genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine. The hallmark feature of CF is the accumulation of thick mucus in different organs. Long-term issues include difficulty breathing and coughing up mucus as a result of frequent lung infections. Other signs and symptoms may include sinus infections, poor growth, fatty stool, clubbing of the fingers and toes, and infertility in most males. Different people may have different degrees of symptoms.
Karl Richter was a German conductor, choirmaster, organist, and harpsichordist.
Sir Stephen John Cleobury was an English organist and music director. He worked with the Choir of King's College, Cambridge, where he served as music director from 1982 to 2019, and with the BBC Singers.
Sir David Valentine Willcocks, was a British choral conductor, organist, composer and music administrator. He was particularly well known for his association with the Choir of King's College, Cambridge, which he directed from 1957 to 1974, making frequent broadcasts and recordings. Several of the descants and carol arrangements he wrote for the annual service of Nine Lessons and Carols were published in the series of books Carols for Choirs which he edited along with Reginald Jacques and John Rutter. He was also director of the Royal College of Music in London.
Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.
Dorothy Hansine Andersen was the American physician and researcher who first identified and named cystic fibrosis. During her almost thirty year tenure at Babies Hospital of Columbia-Presbyterian Medical Center, Andersen not only identified CF and its inheritance through a recessive gene, she was also at the forefront of developing diagnostic tests and life-extending treatments for the disease. Andersen was also active in researching other diseases that are diagnosed in children. She was the first to describe Glycogen storage disease type IV, which, in recognition of her contributions, became known as Andersen's Disease. Her research on heart malformations informed the development of open heart surgery and the training of new surgeons.
Joshua Rifkin is an American conductor, pianist, and musicologist. He is currently a professor of music at Boston University. As a performer, he has recorded music by composers from Antoine Busnois to Silvestre Revueltas; as a scholar he has published research on composers from the Renaissance to the 20th century.
Grégory Jean-Paul Lemarchal, known professionally as Grégory Lemarchal, was a French singer who rose to fame by winning the fourth series of the reality television show Star Academy, which was broadcast on the TF1.
The Passio secundum Joannem or St John Passion, BWV 245, is a Passion or oratorio by Johann Sebastian Bach, the earliest of the surviving Passions by Bach. It was written during his first year as director of church music in Leipzig and was first performed on 7 April 1724, at Good Friday Vespers at the St. Nicholas Church.
The Cystic Fibrosis Foundation (CFF) is a 501(c)(3) non-profit organization in the United States established to provide the means to cure cystic fibrosis (CF) and ensure that those living with CF live long and productive lives. The Foundation provides information about cystic fibrosis and finances CF research that aims to improve the quality of life for people with the disease. The Foundation also engages in legislative lobbying for cystic fibrosis.
Johann Sebastian Bach's Magnificat, BWV 243, is a musical setting of the biblical canticle Magnificat. It is scored for five vocal parts, and a Baroque orchestra including trumpets and timpani. It is the first major liturgical composition on a Latin text by Bach.
Cutting Edge is a British TV documentary series broadcast by Channel 4. It had been Channel 4's flagship documentary series between 1990 and 2017 that focused on political and social issues.
The St Mark Passion, BWV 247, is a lost Passion setting by Johann Sebastian Bach, first performed in Leipzig on Good Friday, 23 March 1731. Though Bach's music is lost, the libretto by Picander is still extant, and from this, the work can to some degree be reconstructed.
Nick van Bloss is an English classical pianist and author who has Tourette syndrome. He studied at the Royal College of Music in London.
The Bach Choir is a large independent musical organisation founded in London, England in 1876 to give the first performance of J. S. Bach's Mass in B minor in Britain.
Walker George Films, founded in 2005 by Stephen Walker and Sally George, is a production company producing films for British television, including the BBC, ITV and Channel 4.
Christopher Stephen Varcoe is an English classical bass-baritone singer, appearing internationally in opera and concert, known for Baroque and contemporary music and a notable singer of Lieder.
Ivacaftor is a medication used to treat cystic fibrosis in people with certain mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, who account for 4–5% cases of cystic fibrosis. It is also included in combination medications, lumacaftor/ivacaftor, tezacaftor/ivacaftor, and elexacaftor/tezacaftor/ivacaftor which are used to treat people with cystic fibrosis.
Gustav Classens was a German conductor who shaped musical life in Bonn. He was municipal music director and conductor of the Beethoven Orchester Bonn from 1933 to 1949, continuing concerts during World War II and reviving them after the war. He was then for decades conductor of the choir Chor der Bonner Bach-Gemeinschaft that he founded.
