Allometric engineering

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Original population is represented in white and novel engineered populations are shown in grey. Allometric shifts will increase the overall variation in one trait relative to the other breaking their typical correlation Allometric shifts.jpg
Original population is represented in white and novel engineered populations are shown in grey. Allometric shifts will increase the overall variation in one trait relative to the other breaking their typical correlation

Allometric engineering is the process of experimentally shifting the scaling relationships, for body size or shape, in a population of organisms. More specifically, the process of experimentally breaking the tight covariance evident among component traits of a complex phenotype by altering the variance of one trait relative to another. Typically, body size is one of the two traits. The measurements of the two traits are plotted against each other and the scaling relationship can be represented as: . Manipulations of this sort alter the scaling relationships either by shifting the intercept (b), slope (m) or both to create novel variants (see: Allometry, for more details). These novel variants can then be tested for differences in performance or fitness. Through careful testing, one could sequentially test each component of a trait suite to determine how each part contributes to the function of the entire complex phenotype, and ultimately the fitness of the organism. This technique allows for comparison within or among biological groups differing in size by adjusting morphology to match one another and comparing their performances. [1]

Contents

Examples and application

Lack's hypothesis

Allometric engineering has been used to test David Lack's hypothesis in the lizard Sceloporus occidentalis . [1] In this study, two populations were "engineered" to fit the morphology of the other by manipulating egg yolk quantity, removing effect of size difference between groups. After manipulation, they found that speed was inversely proportional to body size.

Nature versus nurture

Maternal investment was "allometrically engineered" by surgically removing an ovary in cockroaches ( Diploptera punctata ). [2] This effectively reduced number of progeny and increased resource allocation to each offspring. They coupled this manipulation with group effects (faster development in large groups), and found that maternal investment can overcome group effect.

Sexual selection

The male long-tailed widowbird (Euplectes progne) has exceptionally long tail feathers roughly half a meter in length. [3] Male tail feathers were cropped and glued and those with artificially enhanced tail lengths secured the most matings, demonstrating female preference.

Natural selection

The fly Zonosemata vittigera has a banding pattern on its wings that was found to mimic movements of a jumping spider. Greene et al. engineered novel phenotypes, breaking correlation between a behavior and morphology, by cutting and transplanting the wings of this fly with the common housefly. [4] This manipulation demonstrated that it was behavior coupled with the banding pattern that deterred jumping spiders from attacking, though not other predators.

Methods

Current uses have involved truncation or cropping, yolk manipulation, hormonal treatments, maternal allocation, temperature manipulation, or altering the nutritional states. [5] Each method undoubtedly has its merits and pitfalls to consider before designing an experiment, but these techniques are opening new avenues of research in comparative and evolutionary biology.

See also

Related Research Articles

Genomic imprinting is an epigenetic phenomenon that causes genes to be expressed in a parent-of-origin-specific manner. Genes however, can also be partially imprinted. Partial imprinting happens when alleles from both parents are differently expressed rather than complete expression and complete suppression of one parents allele. Forms of genomic imprinting have been demonstrated in fungi, plants and animals. As of 2014, there are about 150 imprinted genes known in the mouse and about half that in humans. In 2019, 260 imprinted genes have been reported in mice and 228 in humans.

Sexual selection Mode of natural selection involving the choosing of and competition for mates

Sexual selection is a mode of natural selection in which members of one biological sex choose mates of the other sex to mate with, and compete with members of the same sex for access to members of the opposite sex. These two forms of selection mean that some individuals have greater reproductive success than others within a population, for example because they are more attractive or prefer more attractive partners to produce offspring. For instance, in the breeding season, sexual selection in frogs occurs with the males first gathering at the water's edge and making their mating calls: croaking. The females then arrive and choose the males with the deepest croaks and best territories. In general, males benefit from frequent mating and monopolizing access to a group of fertile females. Females can have a limited number of offspring and maximize the return on the energy they invest in reproduction.

Sexual dimorphism Condition where the two sexes of the same species exhibit different characteristics

Sexual dimorphism is the condition where the two sexes of the same species exhibit different characteristics beyond the differences in their sexual organs. The condition occurs in many animals and some plants. Differences may include secondary sex characteristics, size, weight, colour, markings, and may also include behavioral and cognitive differences. These differences may be subtle or exaggerated, and may be subjected to sexual selection and natural selection. The opposite of dimorphism is monomorphism.

A maternal effect is a situation where the phenotype of an organism is determined not only by the environment it experiences and its genotype, but also by the environment and genotype of its mother. In genetics, maternal effects occur when an organism shows the phenotype expected from the genotype of the mother, irrespective of its own genotype, often due to the mother supplying messenger RNA or proteins to the egg. Maternal effects can also be caused by the maternal environment independent of genotype, sometimes controlling the size, sex, or behaviour of the offspring. These adaptive maternal effects lead to phenotypes of offspring that increase their fitness. Further, it introduces the concept of phenotypic plasticity, an important evolutionary concept. It has been proposed that maternal effects are important for the evolution of adaptive responses to environmental heterogeneity.

Directional selection

In population genetics, directional selection, or positive selection is a mode of natural selection in which an extreme phenotype is favored over other phenotypes, causing the allele frequency to shift over time in the direction of that phenotype. Under directional selection, the advantageous allele increases as a consequence of differences in survival and reproduction among different phenotypes. The increases are independent of the dominance of the allele, and even if the allele is recessive, it will eventually become fixed.

The metabolic theory of ecology (MTE) is an extension of Metabolic Scaling Theory and Kleiber's law. It posits that the metabolic rate of organisms is the fundamental biological rate that governs most observed patterns in ecology. MTE is part of a larger set of theory known as metabolic scaling theory that attempts to provide a unified theory for the importance of metabolism in driving pattern and process in biology from the level of cells all the way to the biosphere.

Stabilizing selection Type of selection in evolution where a trait stabilizes around the average value

Stabilizing selection is a type of natural selection in which the population mean stabilizes on a particular non-extreme trait value. This is thought to be the most common mechanism of action for natural selection because most traits do not appear to change drastically over time. Stabilizing selection commonly uses negative selection to select against extreme values of the character. Stabilizing selection is the opposite of disruptive selection. Instead of favoring individuals with extreme phenotypes, it favors the intermediate variants. Stabilizing selection tends to remove the more severe phenotypes, resulting in the reproductive success of the norm or average phenotypes. This means that most common phenotype in the population is selected for and continues to dominate in future generations. Because most traits change little over time, stabilizing selection is thought to be the most common type of selection in most populations.

Allometry Study of the relationship of body size to shape, anatomy, physiology, and behavior

Allometry is the study of the relationship of body size to shape, anatomy, physiology and finally behaviour, first outlined by Otto Snell in 1892, by D'Arcy Thompson in 1917 in On Growth and Form and by Julian Huxley in 1932.

The thrifty phenotype hypothesis says that reduced fetal growth is strongly associated with a number of chronic conditions later in life. This increased susceptibility results from adaptations made by the fetus in an environment limited in its supply of nutrients. The thrifty phenotype is a component of the fetal origins hypothesis. These chronic conditions include coronary heart disease, stroke, diabetes, and hypertension.

Stalk-eyed fly Family of dipteran insects with antennae located on eyestalks

Stalk-eyed flies are insects of the fly family Diopsidae. The family is distinguished from most other flies by the possession of "eyestalks": projections from the sides of the head with the eyes at the end. Some fly species from other families such as Drosophilidae, Platystomatidae, Richardiidae, and Tephritidae have similar heads, but the unique character of the Diopsidae is that their antennae are located on the stalk, rather than in the middle of the head as in all other flies.

Canalisation (genetics)

Canalisation is a measure of the ability of a population to produce the same phenotype regardless of variability of its environment or genotype. It is a form of evolutionary robustness. The term was coined in 1942 by C. H. Waddington to capture the fact that "developmental reactions, as they occur in organisms submitted to natural selection...are adjusted so as to bring about one definite end-result regardless of minor variations in conditions during the course of the reaction". He used this word rather than robustness to take into account that biological systems are not robust in quite the same way as, for example, engineered systems.

Sexual conflict Term in evolutionary biology

Sexual conflict or sexual antagonism occurs when the two sexes have conflicting optimal fitness strategies concerning reproduction, particularly over the mode and frequency of mating, potentially leading to an evolutionary arms race between males and females. In one example, males may benefit from multiple matings, while multiple matings may harm or endanger females, due to the anatomical differences of that species.

Neriidae

The Neriidae are a family of true flies (Diptera) closely related to the Micropezidae. Some species are known as cactus flies, while others have been called banana stalk flies and the family was earlier treated as subfamily of the Micropezidae which are often called stilt-legged flies. Neriids differ from micropezids in having no significant reduction of the fore legs. Neriids breed in rotting vegetation, such as decaying tree bark or rotting fruit. About 100 species are placed in 19 genera. Neriidae are found mainly in tropical regions, but two North American genera occur, each with one species, and one species of Telostylinus occurs in temperate regions of eastern Australia.

Evolutionary physiology Study of changes over time in a populations physiological characteristics in response to natural selection

Evolutionary physiology is the study of the biological evolution of physiological structures and processes; that is, the manner in which the functional characteristics of individuals in a population of organisms have responded to natural selection across multiple generations during the history of the population. It is a sub-discipline of both physiology and evolutionary biology. Practitioners in the field come from a variety of backgrounds, including physiology, evolutionary biology, ecology, and genetics.

Rensch's rule is a biological rule on allometrics, concerning the relationship between the extent of sexual size dimorphism and which sex is larger. Across species within a lineage, size dimorphism increases with increasing body size when the male is the larger sex, and decreases with increasing average body size when the female is the larger sex. The rule was proposed by the evolutionary biologist Bernhard Rensch in 1950.

Red-collared widowbird

The red-collared widowbird is a species of bird in the family Ploceidae. Red-collared widowbirds are found in grasslands and bush clearings in Eastern and Southern Africa. They are known for their long tails and brilliant red badges, both which act as sexual ornaments. They are often associated with other widowbird and bishop species. They are polygynous, where males acquisition of territory is an important determinant in their access to mates. Red-collared widowbirds have a wide range and there is little concern in terms of conservation status.

Long-tailed widowbird

The long-tailed widowbird, also known as the "Sakabula", is a species of bird in the family Ploceidae. The species are found in Angola, Botswana, the DRCongo, Kenya, Lesotho, South Africa, Swaziland, and Zambia. The long-tailed widowbird is a medium-sized bird and one of the most common in the territories it inhabits. Adult breeding males are almost entirely black with orange and white shoulders (epaulets), long, wide tails, and a bluish white bill. Females are rather inconspicuous, their feathers streaked tawny and black with pale patches on the chest, breast and back, narrow tail feathers, and horn-colored bills.

<i>Scathophaga stercoraria</i>

Scathophaga stercoraria, commonly known as the yellow dung fly or the golden dung fly, is one of the most familiar and abundant flies in many parts of the Northern Hemisphere. As its common name suggests, it is often found on the feces of large mammals, such as horses, cattle, sheep, deer, and wild boar, where it goes to breed. The distribution of S. stercoraria is likely influenced by human agriculture, especially in northern Europe and North America. The Scathophaga are integral in the animal kingdom due to their role in the natural decomposition of dung in fields. They are also very important in the scientific world due to their short life cycles and susceptibility to experimental manipulations; thus, they have contributed significant knowledge about animal behavior.

Transgenerational epigenetic inheritance

Transgenerational epigenetic inheritance, (TEI), is the transmission of epigenetic markers from one organism to the next that affects the traits of offspring without alteration of the primary structure of DNA —in other words, epigenetically. The less precise term "epigenetic inheritance" may cover both cell–cell and organism–organism information transfer. Although these two levels of epigenetic inheritance are equivalent in unicellular organisms, they may have distinct mechanisms and evolutionary distinctions in multicellular organisms.

Telostylinus angusticollis is a fly in the family Neriidae of the insect order Diptera. They are typically found on the east coast of Australia near rotting vegetation. Aggregating on the rotting bark of trees such as Acacia longigolia and other trees in New South Wales and southern Queensland. T. angusticollis flies found in the wild have accelerated speeds of development and age of mortality when compared to those in captivity.

References

  1. 1 2 Sinervo, B.; Huey, R. (1990). "Allometric Engineering: An Experimental Test of the Causes of Interpopulational Differences in Performance" (PDF). Science . 248 (4959): 1106–1109. Bibcode:1990Sci...248.1106S. doi:10.1126/science.248.4959.1106. PMID   17733374. S2CID   3068221.
  2. Holbrook, G.; Schal, C. (2004). "Maternal investment affects offspring phenotypic plasticity in a viviparous cockroach". PNAS. 101 (15): 5595–5597. Bibcode:2004PNAS..101.5595H. doi:10.1073/pnas.0400209101. PMC   397435 . PMID   15064397.
  3. Andersson, Malte (1982). "Female choice selects for extreme tail length in a widowbird". Nature . 299 (5886): 818–820. Bibcode:1982Natur.299..818A. doi:10.1038/299818a0. S2CID   4334275.
  4. Greene, E.; Orsak, L. & Whitman, D. (1987). "A Tephritid Fly Mimics the Territorial Displays of its Jumping Spider Predators". Science . 236 (4799): 310–312. Bibcode:1987Sci...236..310G. doi:10.1126/science.236.4799.310. PMID   17755555. S2CID   17023853. see: Tephritid fly.
  5. Sinervo, B. (1993). "The Effect of Offspring Size on Physiology and Life History". BioScience. 43 (4): 210–218. doi:10.2307/1312121. JSTOR   1312121.

Further reading