Anita Corbett

Last updated
Anita Corbett
Born
Anita Hargrave Corbett
Alma mater Colgate University (BS)
Vanderbilt University (PhD)
Scientific career
Fields mRNA processing
Polyadenylation
Gene expression
Intellectual disability [1]
Institutions Emory University
Thesis Regulation of the catalytic cycle of topoisomerase II  (1992)
Doctoral advisor Neil Osheroff  [ Wikidata ]
Website biology.emory.edu/corbett OOjs UI icon edit-ltr-progressive.svg

Anita Hargrave Corbett is an American biochemist who is the Samuel C. Dobbs Professor in the Department of Biology at Emory University. [1] [2] Her research investigates the molecular basis for disease, the regulation of protein import and mRNA export. She is a Fellow of the American Association for the Advancement of Science and the American Society for Biochemistry and Molecular Biology.

Contents

Early life and education

As a high school student, Corbett took part in the National Science Bowl. She has said that her high school chemistry teacher made her believe she could be a chemist, and encouraged her to take AP Chemistry.[ citation needed ] She was an undergraduate student at Colgate University, [3] where she became interested in biochemistry, and studied the activation and inhibition of bovine carbonic anhydrase. [4] Corbett was a doctoral researcher at Vanderbilt University, [5] where she studied the regulation of topoisomerase II supervised by Neil Osheroff  [ Wikidata ]. [6]

Research and career

After her PhD, she moved to Harvard Medical School as a postdoctoral researcher with Pamela Silver. [7]

In 2003, Corbett was the first woman to be tenured in the Emory University School of Medicine. [5] Her research investigates the regulation of biological processes, including the import of proteins and export of mRNA. She studies these processes using model systems of yeast, Drosophila and laboratory mice. [8] [9] It is well understood that disease is linked to mutations in genes encoding structural RNA exosome subunits. [5] Corbett linked mutations in one particular subunit, EXOSC5, to poor clinical outcomes. [10] She has extensively investigated RNA-binding proteins, which are involved with various stages of gene expression. [11]

Awards and honors

Selected publications

Related Research Articles

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References

  1. 1 2 Anita Corbett publications indexed by Google Scholar OOjs UI icon edit-ltr-progressive.svg
  2. Anita Corbett publications from Europe PubMed Central
  3. "Anita H. Corbett, PhD". biology.emory.edu. Retrieved 2023-05-02.
  4. Rowlett, R S; Gargiulo, N J; Santoli, F A; Jackson, J M; Corbett, A H (1991-01-15). "Activation and inhibition of bovine carbonic anhydrase III by dianions". Journal of Biological Chemistry. 266 (2): 933–941. doi: 10.1016/S0021-9258(17)35263-8 . ISSN   0021-9258. PMID   1898739.
  5. 1 2 3 4 "Corbett goes the extra mile to support young scientists". asbmb.org. Retrieved 2023-05-02.
  6. Corbett, Anita Hargrave (1992). Regulation of the catalytic cycle of topoisomerase II (PhD thesis). OCLC   30332920. ProQuest   303996778.
  7. 1 2 Anon (2019). "Nature Awards give mentors the recognition, funding, and 'street cred' they need". springernature.com. Retrieved 2023-05-02.
  8. "Professor Anita H. Corbett". rnasociety.org. Retrieved 2023-05-02.
  9. Corbett, Anita H. (2015-04-01). "A long and winding road to the RNA world". RNA. 21 (4): 590–591. doi:10.1261/rna.049841.115. ISSN   1355-8382. PMC   4371294 . PMID   25780152.
  10. Slavotinek, Anne; Misceo, Doriana; Htun, Stephanie; Mathisen, Linda; Frengen, Eirik; Foreman, Michelle; Hurtig, Jennifer E.; Enyenihi, Liz; Sterrett, Maria C.; Leung, Sara W.; Schneidman-Duhovny, Dina; Estrada-Veras, Juvianee; Duncan, Jacque L.; Haaxma, Charlotte A.; Kamsteeg, Erik-Jan (2020-08-03). "Biallelic variants in the RNA exosome gene EXOSC5 are associated with developmental delays, short stature, cerebellar hypoplasia and motor weakness". Human Molecular Genetics. 29 (13): 2218–2239. doi:10.1093/hmg/ddaa108. ISSN   1460-2083. PMC   7399534 . PMID   32504085.
  11. "Anita Corbett". biology.emory.edu. Retrieved 2023-05-02.
  12. "Laney Graduate School announces Eleanor Main Graduate Mentor Awards | Emory University | Atlanta GA". news.emory.edu. Retrieved 2023-05-02.
  13. "Emory faculty named 2022 fellows of the American Association for the Advancement of Science | Emory University | Atlanta GA". news.emory.edu. Retrieved 2023-05-02.
  14. "2022 ASBMB fellows named". asbmb.org. Retrieved 2023-05-02.
  15. "2022 RNA Society Award for Excellence in Inclusive Leadership". rnasociety.org. Retrieved 2023-05-02.