Anita Corbett | |
---|---|
Born | Anita Hargrave Corbett |
Alma mater | Colgate University (BS) Vanderbilt University (PhD) |
Scientific career | |
Fields | mRNA processing Polyadenylation Gene expression Intellectual disability [1] |
Institutions | Emory University |
Thesis | Regulation of the catalytic cycle of topoisomerase II (1992) |
Doctoral advisor | Neil Osheroff |
Website | biology |
Anita Hargrave Corbett is an American biochemist who is the Samuel C. Dobbs Professor in the Department of Biology at Emory University. [1] [2] Her research investigates the molecular basis for disease, the regulation of protein import and mRNA export. She is a Fellow of the American Association for the Advancement of Science and the American Society for Biochemistry and Molecular Biology.
As a high school student, Corbett took part in the National Science Bowl. She has said that her high school chemistry teacher made her believe she could be a chemist, and encouraged her to take AP Chemistry.[ citation needed ] She was an undergraduate student at Colgate University, [3] where she became interested in biochemistry, and studied the activation and inhibition of bovine carbonic anhydrase. [4] Corbett was a doctoral researcher at Vanderbilt University, [5] where she studied the regulation of topoisomerase II supervised by Neil Osheroff . [6]
After her PhD, she moved to Harvard Medical School as a postdoctoral researcher with Pamela Silver. [7]
In 2003, Corbett was the first woman to be tenured in the Emory University School of Medicine. [5] Her research investigates the regulation of biological processes, including the import of proteins and export of mRNA. She studies these processes using model systems of yeast, Drosophila and laboratory mice. [8] [9] It is well understood that disease is linked to mutations in genes encoding structural RNA exosome subunits. [5] Corbett linked mutations in one particular subunit, EXOSC5, to poor clinical outcomes. [10] She has extensively investigated RNA-binding proteins, which are involved with various stages of gene expression. [11]
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