Ann Shulgin | |
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 Shulgin in 2011 | |
| Born | Laura Ann Gotlieb March 22, 1931 Wellington, New Zealand |
| Died | July 9, 2022 (aged 91) Lafayette, California |
| Occupation | Author |
| Nationality | American |
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| Website | |
| shulginresearch | |
Laura Ann Shulgin ( née Gotlieb; March 22, 1931 – July 9, 2022) [2] was an American author and the wife of chemist Alexander Shulgin, with whom she wrote PiHKAL and TiHKAL . [3]
Laura Ann Gotlieb [4] was born in Wellington, New Zealand, to parents Bernard Gotlieb and Gwen Ormiston, but grew up in the village Opicina outside the Italian city Trieste. Her father was U.S. Consul in Trieste for six years before World War II. [5] [6] [4] Later in her childhood she lived in the U.S., Cuba, and Canada. She studied art and became an artist, married an artist and had a child, and they later divorced. She had two more marriages ending in divorce and had three more children. Ann went back to work as a medical transcriber, and met Alexander ("Sasha") Shulgin in 1978; they were married on 4 July 1981 in their back yard. [4]
She worked as a lay therapist with psychedelic substances such as MDMA and 2C-B in therapeutic settings while these drugs were still legal. [7] In her writings she stressed the potential of these drugs from a Jungian psychoanalytic perspective, as well as their use in combination with hypnotherapy. She often appeared as a speaker at conventions and continued to advocate the use of psychedelics in therapeutic contexts.[ citation needed ]
Together with her husband she authored the books PiHKAL and TiHKAL . [7] They developed a systematic way of ranking the effects of the various drugs, known as the Shulgin Rating Scale, with a vocabulary to describe the visual, auditory and physical sensations. She also contributed to the books Thanatos to Eros: 35 Years of Psychedelic Exploration, Entheogens and the Future of Religion, Ecstasy: The Complete Guide, The Secret Chief Revealed, Higher Wisdom: Eminent Elders Explore the Continuing Impact of Psychedelics, and Manifesting Minds: A Review of Psychedelics in Science, Medicine, Sex, and Spirituality.[ citation needed ]
According to her daughter, Shulgin had been in ill health because of chronic obstructive pulmonary disease. Shulgin died July 9, 2022, at her and her late husband's San Francisco Bay Area residence. [8]
Alexander Theodore "Sasha" Shulgin was an American medicinal chemist, biochemist, organic chemist, pharmacologist, psychopharmacologist, and author. He is credited with introducing MDMA, commonly known as "ecstasy", via academic journals and papers to psychologists in the late 1970s for psychopharmaceutical use and for the discovery, synthesis and personal bioassay of over 230 psychoactive compounds for their psychedelic and entactogenic potential.
PiHKAL: A Chemical Love Story is a book by Dr. Alexander Shulgin and Ann Shulgin, published in 1991. The subject of the work is psychoactive phenethylamine chemical derivatives, notably those that act as psychedelics and/or empathogen-entactogens. The main title, PiHKAL, is an acronym that stands for "Phenethylamines I Have Known and Loved."
2C-E is a psychedelic phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin and documented in his book PiHKAL. Like the other substances in its family, it produces sensory and cognitive effects in its physical reactions with living organisms.
TIHKAL: The Continuation is a 1997 book written by Alexander Shulgin and Ann Shulgin about a family of psychoactive drugs known as tryptamines. A sequel to PIHKAL: A Chemical Love Story, TIHKAL is an acronym that stands for "Tryptamines I Have Known and Loved".
2C-C is a psychedelic drug of the 2C family. It was first synthesized by Alexander Shulgin, sometimes used as an entheogen. In his book PiHKAL , Shulgin lists the dosage range as 20–40 mg. 2C-C is usually taken orally, but may also be insufflated. 2C-C is schedule I of section 202(c) of the Controlled Substances Act in the United States, signed into law as of July, 2012 under the Food and Drug Administration Safety and Innovation Act.
α-Ethyltryptamine, also known as etryptamine, is a psychedelic, stimulant, and entactogenic drug of the tryptamine class. It was originally developed and marketed as an antidepressant under the brand name Monase by Upjohn in the 1960s.
2C-T-8 is a psychedelic phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin, sometimes used as an entheogen.
2C-N (2,5-dimethoxy-4-nitrophenethylamine) is a psychedelic phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin.
Diisopropyltryptamine is a psychedelic hallucinogenic drug of the tryptamine family that has a unique effect. While the majority of hallucinogens affect the visual sense, DiPT is primarily aural.
4-HO-DET, also known as 4-hydroxy-diethyl-tryptamine, CZ-74, is a hallucinogenic drug and psychedelic compound of moderate duration. 4-HO-DET is a substituted tryptamine, structurally related to psilocin, ethocybin, and 4-HO-DIPT.
N-methyl-N-isopropyltryptamine (MiPT) is a psychedelic tryptamine, closely related to DMT, DiPT and miprocin. It was first synthesized by David Repke in 1984 and was subsequently evaluated and described in Alexander Shulgin's 1997 book TiHKAL.
2C-T is a psychedelic and hallucinogenic drug of the 2C family. It is used by some as an entheogen. It has structural and pharmacodynamic properties similar to the drugs mescaline and 2C-T-2.
3,4-Methylenedioxy-N-hydroxyamphetamine is an entactogen, psychedelic, and stimulant of the phenethylamine and amphetamine chemical classes. It is the N-hydroxy homologue of MDA, and the N-desmethyl homologue of MDHMA. MDOH was first synthesized and assayed by Alexander Shulgin. In his book PiHKAL, Shulgin listed the dosage range as 100–160 mg, and the duration as approximately 3–6 hours. He describes MDOH as being very psychedelic and producing increased pleasure in beauty and nature. He also mentioned several negative side effects also seen with MDMA ("Ecstasy") such as difficulty urinating and internal dryness.
Cyclopropylmescaline is a lesser-known psychedelic drug. CPM was first synthesized by Alexander Shulgin. In his book PiHKAL, the dosage range is listed as 60–80 mg and the duration listed as 12–18 hours. CPM produces closed-eye imagery, visuals, and fantasies. It also causes enhancement of music. Very little data exists about the pharmacological properties, metabolism, and toxicity of CPM.
2C-H (2,5-dimethoxyphenethylamine) is a lesser-known substituted phenethylamine of the 2C family.
3,4-Methylenedioxy-N-hydroxy-N-methylamphetamine is an entactogen, psychedelic, and stimulant of the phenethylamine and amphetamine chemical classes. It is the N-hydroxy homologue of MDMA ("Ecstasy"), and the N-methyl homologue of MDOH. MDHMA was first synthesized and assayed by Alexander Shulgin. In his book PiHKAL, Shulgin listed the dosage range as 100–160 mg, and the duration as approximately 4–8 hours. He describes MDHMA as causing entactogenic and open MDMA-like effects, easing communication, and increasing appreciation of the senses.
Thiobuscaline, or 3,5-dimethoxy-4-butylthiophenethylamine]], is a lesser-known psychedelic drug.
N-Methyl-2-methoxy-4,5-methylenedioxyamphetamine is a psychedelic drug of the amphetamine class. It is the N-methylated derivative of MMDA-2, and it is also an analog of MDMA and 6-methyl-MDA.
Leo Zeff was an American psychologist and psychotherapist in Oakland, California who pioneered the use of LSD, ecstasy (MDMA), and other psychoactive drugs in psychotherapy in the 1970s.
2C-Se is a lesser-known psychedelic drug. It was originally named by Alexander Shulgin as described in his book PiHKAL. Shulgin considered 2C-Se to be around three times the potency of mescaline, but was too concerned about toxicity to test it extensively, though he considered it noteworthy as the only psychedelic drug to contain a selenium atom.
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