Besifovir

Last updated
Besifovir
Besifovir.svg
Clinical data
Routes of
administration 		Oral
ATC code
Identifiers
  • [({1-[(2-Amino-9H-purin-9-yl)methyl]cyclopropyl}oxy)methyl]phosphonic acid
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
Formula C10H14N5O4P
Molar mass 299.227 g·mol−1
3D model (JSmol)
  • NC1=NC=C2N=CN(CC3(OCP(O)(O)=O)CC3)C2=N1
  • InChI=InChI=1S/C10H14N5O4P/c11-9-12-3-7-8(14-9)15(5-13-7)4-10(1-2-10)19-6-20(16,17)18/h3,5H,1-2,4,6H2,(H2,11,12,14)(H2,16,17,18) X mark.svgN
  • Key:KDNSSKPZBDNJDF-UHFFFAOYSA-N X mark.svgN
 X mark.svgNYes check.svgY  (what is this?)

Besifovir (INN) is an investigational medication to treat hepatitis B virus (HBV) infection. It is a novel and potent acyclic nucleotide phosphonate with a similar chemical structure to adefovir and tenofovir. [2]

References

  1. ↑ WHO International Working Group for Drug Statistics Methodology (August 27, 2008). "ATC/DDD Classification (FINAL): New ATC 5th level codes". WHO Collaborating Centre for Drug Statistics Methodology. Archived from the original on 2008-05-06. Retrieved 2008-09-05.
  2. ↑ Lin CL, Yang HC, Kao JH (4 January 2016). "Hepatitis B virus: new therapeutic perspectives". Liver Int. 36 (Supplement S1): 85–92. doi: 10.1111/liv.13003 . PMID   26725903.
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