CAMK1G (gene)

CAMK1G
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2JAM
Identifiers
Aliases	CAMK1G , CLICK3, CLICKIII, VWS1, dJ272L16.1, calcium/calmodulin dependent protein kinase IG
External IDs	OMIM: 614994; MGI: 2388073; HomoloGene: 48706; GeneCards: CAMK1G; OMA:CAMK1G - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	209,613,939 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	193,052,606 bp
RNA expression pattern
	Top expressed in
	frontal pole; ; Brodmann area 10; ; right frontal lobe; ; Brodmann area 9; ; cingulate gyrus; ; anterior cingulate cortex; ; nucleus accumbens; ; middle frontal gyrus; ; Region I of hippocampus proper; ; superior frontal gyrus;
	Top expressed in
	ventromedial nucleus; ; superior frontal gyrus; ; visual cortex; ; primary visual cortex; ; olfactory tubercle; ; pontine nuclei; ; primary motor cortex; ; central gray substance of midbrain; ; nucleus accumbens; ; nucleus of stria terminalis;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity ; nucleotide binding ; protein kinase activity ; protein serine/threonine kinase activity ; catalytic activity ; ATP binding ; kinase activity ; calmodulin-dependent protein kinase activity ; calmodulin binding ;
Cellular component	cytoplasm ; calcium- and calmodulin-dependent protein kinase complex ; neuron projection ; Golgi membrane ; plasma membrane ; Golgi apparatus ; membrane ; endomembrane system ; intracellular anatomical structure ;
Biological process	protein phosphorylation ; metabolism ; phosphorylation ; peptidyl-serine phosphorylation ; peptidyl-threonine phosphorylation ; intracellular signal transduction ;
	Sources:Amigo / QuickGO
Orthologs
	57172
	215303
	ENSG00000008118
	ENSMUSG00000016179
	Q96NX5
	Q91VB2
	NM_020439
	NM_144817
	NP_065172
	NP_659066
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 09, 2024

Calcium/calmodulin dependent protein kinase IG is a protein that in humans is encoded by the CAMK1G gene. ^[5]

Function

This gene encodes a protein similar to calcium/calmodulin dependent protein kinase, however, its exact function is not known. [provided by RefSeq, Jul 2008].

Related Research Articles

Calcium/calmodulin-dependent protein kinase type II subunit alpha (CAMKIIα), a.k.a.Ca²⁺/calmodulin-dependent protein kinase II alpha, is one subunit of CamKII, a protein kinase (i.e., an enzyme which phosphorylates proteins) that in humans is encoded by the CAMK2A gene.

Calcium/calmodulin-dependent protein kinase type II beta chain is an enzyme that in humans is encoded by the CAMK2B gene.

Cyclic AMP-dependent transcription factor ATF-1 is a protein that in humans is encoded by the ATF1 gene.

Peripheral plasma membrane protein CASK is a protein that in humans is encoded by the CASK gene. This gene is also known by several other names: CMG 2, calcium/calmodulin-dependent serine protein kinase 3 and membrane-associated guanylate kinase 2. CASK gene mutations are the cause of XL-ID with or without nystagmus and MICPCH, an X-linked neurological disorder.

Calcium/calmodulin-dependent protein kinase type IV is an enzyme that in humans is encoded by the CAMK4 gene.

Calcium/calmodulin-dependent protein kinase type II gamma chain is an enzyme that in humans is encoded by the CAMK2G gene.

Calpain-1 catalytic subunit(CANP 1) is a protein that in humans is encoded by the CAPN1 gene.

Calcium/calmodulin-dependent protein kinase type 1 is an enzyme that in humans is encoded by the CAMK1 gene.

1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 is an enzyme that in humans is encoded by the PLCB3 gene.

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 is a protein that in humans is encoded by the GNG2 gene.

Calcium/calmodulin-dependent protein kinase type II delta chain is an enzyme that in humans is encoded by the CAMK2D gene.

Protein tyrosine phosphatase non-receptor type 7 is an enzyme that in humans is encoded by the PTPN7 gene.

Eukaryotic elongation factor-2 kinase, also known as calmodulin-dependent protein kinase III (CAMKIII) and calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase, is an enzyme that in humans is encoded by the EEF2K gene.

Integrin beta-1-binding protein 1 is a protein that in humans is encoded by the ITGB1BP1 gene.

Protein BEX3 is a protein that in humans is encoded by the NGFRAP1 gene.

Calcium/calmodulin-dependent protein kinase kinase 1 is an enzyme that in humans is encoded by the CAMKK1 gene.

Calcium/calmodulin-dependent protein kinase kinase 2 is an enzyme that in humans is encoded by the CAMKK2 gene.

Calcium channel, voltage-dependent, T type, alpha 1H subunit, also known as CACNA1H, is a protein which in humans is encoded by the CACNA1H gene.

Calcium/calmodulin dependent protein kinase II inhibitor 1 is a protein that in humans is encoded by the CAMK2N1 gene.

Sushi domain containing 2 is a protein that in humans is encoded by the SUSD2 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000008118 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000016179 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Calcium/calmodulin dependent protein kinase IG" . Retrieved 2018-08-28.

Takemoto-Kimura S, Terai H, Takamoto M, Ohmae S, Kikumura S, Segi E, Arakawa Y, Furuyashiki T, Narumiya S, Bito H (May 2003). "Molecular cloning and characterization of CLICK-III/CaMKIgamma, a novel membrane-anchored neuronal Ca2+/calmodulin-dependent protein kinase (CaMK)". J. Biol. Chem. 278 (20): 18597–605. doi: 10.1074/jbc.M300578200 . PMID 12637513.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD (November 2009). "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip". Am. J. Hum. Genet. 85 (5): 628–42. doi:10.1016/j.ajhg.2009.10.014. PMC 2775832 . PMID 19913121.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S (October 2010). "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study". Diabetes Care. 33 (10): 2250–3. doi:10.2337/dc10-0452. PMC 2945168 . PMID 20628086.
Pang ZP, Xu W, Cao P, Südhof TC (October 2010). "Calmodulin suppresses synaptotagmin-2 transcription in cortical neurons". J. Biol. Chem. 285 (44): 33930–9. doi: 10.1074/jbc.M110.150151 . PMC 2962493 . PMID 20729199.
Deng M, Wei L, Zuo X, Tian Y, Xie F, Hu P, Zhu C, Yu F, Meng Y, Wang H, Zhang F, Ma H, Ye R, Cheng H, Du J, Dong W, Zhou S, Wang C, Wang Y, Wang J, Chen X, Sun Z, Zhou N, Jiang Y, Liu X, Li X, Zhang N, Liu N, Guan Y, Han Y, Han Y, Lv X, Fu Y, Yu H, Xi C, Xie D, Zhao Q, Xie P, Wang X, Zhang Z, Shen L, Cui Y, Yin X, Cheng H, Liang B, Zheng X, Lee TM, Chen G, Zhou F, Veldink JH, Robberecht W, Landers JE, Andersen PM, Al-Chalabi A, Shaw C, Liu C, Tang B, Xiao S, Robertson J, Zhang F, van den Berg LH, Sun L, Liu J, Yang S, Ju X, Wang K, Zhang X (June 2013). "Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis". Nat. Genet. 45 (6): 697–700. doi:10.1038/ng.2627. PMID 23624525. S2CID 7924012.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000008118 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000016179 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Calcium/calmodulin dependent protein kinase IG" . Retrieved 2018-08-28.

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CAMK1G (gene)

Contents

Function

Related Research Articles

References

Further reading