CBMAR

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CBMAR
Content
DescriptionBeta-lactamase database annotating beta-lactamase based on their characteristics
Data types
captured
Beta-lactamase
Organisms Bacteria
Contact
Primary citation PMID   25475113
Access
Website 14.139.227.92/mkumar/lactamasedb
Miscellaneous
Bookmarkable
entities
yes

CBMAR (Comprehensive β-lactamase Molecular Annotation Resource) is a database focused on the annotation and discovery of novel beta-lactamase genes and proteins in bacteria. [1] Beta-lactamases are characterized on CBMAR using the Ambler Classification system. [2] CBMAR organizes beta-lactamases according to their classes: A, B, C, and D. They are then further categorized by their (i) sequence variability, (ii) antibiotic resistance profile, (iii) inhibitor susceptibility, (iv) active site, (v) family fingerprints, (vi) mutational profile, (vii) variants, (viii) gene location, (ix) phylogenetic tree, etc. The primary sources of database for CBMAR are GenBank and Uniprot. [3] CBMAR is built on an Apache HTTP Server 2.2.17 with MySQL Ver 14.14 and hosted on Ubuntu 11.04 Linux platform.

See also

References

  1. Srivastava, Abhishikha; Singhal, Neelja; Goel, Manisha; Virdi, Jugsharan Singh; Kumar, Manish (2014-01-01). "CBMAR: a comprehensive β-lactamase molecular annotation resource". Database. 2014: bau111. doi:10.1093/database/bau111. ISSN   1758-0463. PMC   4255060 . PMID   25475113.
  2. Ambler, R. P. (1980-05-16). "The Structure of <latex>$\beta$</latex>-Lactamases". Philosophical Transactions of the Royal Society B: Biological Sciences. 289 (1036): 321–331. doi:10.1098/rstb.1980.0049. ISSN   0962-8436. PMID   6109327.
  3. The UniProt Consortium (2011-11-18). "Reorganizing the protein space at the Universal Protein Resource (UniProt)". Nucleic Acids Research. 40 (D1): D71 –D75. doi:10.1093/nar/gkr981. ISSN   0305-1048. PMC   3245120 . PMID   22102590.