CHPF

CHPF
Identifiers
Aliases	CHPF , CHSY2, CSS2, chondroitin polymerizing factor
External IDs	OMIM: 610405 MGI: 106576 HomoloGene: 11574 GeneCards: CHPF
Gene location (Human) Chr. Chromosome 2 (human) [1] Band 2q35 Start 219,538,954 bp [1] End 219,543,809 bp [1]
Gene location (Mouse) Chr. Chromosome 1 (mouse) [2] Band 1 C4|1 39.14 cM Start 75,451,213 bp [2] End 75,455,951 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in anterior pituitary stromal cell of endometrium ascending aorta body of pancreas right coronary artery left ventricle left coronary artery right lobe of liver canal of the cervix left lobe of thyroid gland Top expressed in superior frontal gyrus entorhinal cortex ankle joint yolk sac calvaria spermatocyte lip hippocampus proper cerebellar cortex neural tube More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transferase activity acetylgalactosaminyltransferase activity protein binding metal ion binding glycosyltransferase activity N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity Cellular component cytoplasm integral component of membrane Golgi cisterna membrane cytosol Golgi membrane mitochondrial matrix Golgi apparatus mitochondrion membrane Biological process chondroitin sulfate biosynthetic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79586 74241 Ensembl ENSG00000123989 ENSMUSG00000032997 UniProt Q8IZ52 Q6IQX7 RefSeq (mRNA) NM_001195731 NM_024536 NM_001001565 NM_001001566 RefSeq (protein) NP_001182660 NP_078812 NP_001001565 NP_001001566 Location (UCSC) Chr 2: 219.54 – 219.54 Mb Chr 1: 75.45 – 75.46 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Chondroitin sulfate synthase 2 is an enzyme that in humans is encoded by the CHPF gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000123989 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000032997 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
6. Kitagawa H, Izumikawa T, Uyama T, Sugahara K (Jun 2003). "Molecular cloning of a chondroitin polymerizing factor that cooperates with chondroitin synthase for chondroitin polymerization". J Biol Chem. 278 (26): 23666–71. doi: 10.1074/jbc.M302493200 . PMID   12716890.
7. "Entrez Gene: CHPF chondroitin polymerizing factor".

External links

• Human CHPF genome location and CHPF gene details page in the UCSC Genome Browser .

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Yada T, Gotoh M, Sato T, et al. (2003). "Chondroitin sulfate synthase-2. Molecular cloning and characterization of a novel human glycosyltransferase homologous to chondroitin sulfate glucuronyltransferase, which has dual enzymatic activities". J. Biol. Chem. 278 (32): 30235–47. doi: 10.1074/jbc.M303657200 . PMID   12761225.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC   403697 . PMID   12975309.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC   442147 . PMID   15231747.
• Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC   442148 . PMID   15231748.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.