CHST11

Last updated
CHST11
Identifiers
Aliases CHST11 , C4ST, C4ST-1, C4ST1, HSA269537, carbohydrate (chondroitin 4) sulfotransferase 11, carbohydrate sulfotransferase 11, OCBMD
External IDs OMIM: 610128; MGI: 1927166; HomoloGene: 56808; GeneCards: CHST11; OMA:CHST11 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_018413
NM_001173982

NM_021439

RefSeq (protein)

NP_001167453
NP_060883
NP_060883.1

NP_067414

Location (UCSC) Chr 12: 104.46 – 104.76 Mb Chr 10: 82.82 – 83.03 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Carbohydrate sulfotransferase 11 is an enzyme that in humans is encoded by the CHST11 gene. [5] [6]

Contents

Clinical relevance

Mutations in this gene have been associated to susceptibility for osteoarthritis. [7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000171310 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000034612 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Hiraoka N, Nakagawa H, Ong E, Akama TO, Fukuda MN, Fukuda M (Jun 2000). "Molecular cloning and expression of two distinct human chondroitin 4-O-sulfotransferases that belong to the HNK-1 sulfotransferase gene family". The Journal of Biological Chemistry. 275 (26): 20188–96. doi: 10.1074/jbc.M002443200 . PMID   10781601.
  6. "Entrez Gene: CHST11 carbohydrate (chondroitin 4) sulfotransferase 11".
  7. Zeggini E, Panoutsopoulou K, Southam L, Rayner NW, Day-Williams AG, Lopes MC, et al. (Sep 2012). "Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study". Lancet. 380 (9844): 815–23. doi:10.1016/S0140-6736(12)60681-3. PMC   3443899 . PMID   22763110.

Further reading