Human cloning is the creation of a genetically identical copy of a human. The term is generally used to refer to artificial human cloning, which is the reproduction of human cells and tissue. It does not refer to the natural conception and delivery of identical twins. The possibility of human cloning has raised controversies. These ethical concerns have prompted several nations to pass laws regarding human cloning.
The ovary is an organ in the female reproductive system that produces an ovum. When released, this travels down the fallopian tube into the uterus, where it may become fertilized by a sperm. There is an ovary found on each side of the body. The ovaries also secrete hormones that play a role in the menstrual cycle and fertility. The ovary progresses through many stages beginning in the prenatal period through menopause. It is also an endocrine gland because of the various hormones that it secretes.
In genetics and developmental biology, somatic cell nuclear transfer (SCNT) is a laboratory strategy for creating a viable embryo from a body cell and an egg cell. The technique consists of taking an enucleated oocyte and implanting a donor nucleus from a somatic (body) cell. It is used in both therapeutic and reproductive cloning. In 1996, Dolly the sheep became famous for being the first successful case of the reproductive cloning of a mammal. In January 2018, a team of scientists in Shanghai announced the successful cloning of two female crab-eating macaques from foetal nuclei.
Bone marrow is a semi-solid tissue found within the spongy portions of bones. In birds and mammals, bone marrow is the primary site of new blood cell production. It is composed of hematopoietic cells, marrow adipose tissue, and supportive stromal cells. In adult humans, bone marrow is primarily located in the ribs, vertebrae, sternum, and bones of the pelvis. Bone marrow comprises approximately 5% of total body mass in healthy adult humans, such that a man weighing 73 kg (161 lbs) will have around 3.7 kg (8 lbs) of bone marrow.
The Visible Human Project is an effort to create a detailed data set of cross-sectional photographs of the human body, in order to facilitate anatomy visualization applications. It is used as a tool for the progression of medical findings, in which these findings link anatomy to its audiences. A male and a female cadaver were cut into thin slices, which were then photographed and digitized. The project is run by the U.S. National Library of Medicine (NLM) under the direction of Michael J. Ackerman. Planning began in 1986; the data set of the male was completed in November 1994 and the one of the female in November 1995. The project can be viewed today at the NLM in Bethesda, Maryland. There are currently efforts to repeat this project with higher resolution images but only with parts of the body instead of a cadaver.
Embryo donation is one disposition option for users of in vitro fertilisation with remaining fresh or frozen embryos. It is defined as the giving—generally without compensation—of embryos remaining after in vitro fertilization procedures to recipients for procreative implantation or research. Most IVF users with supernumerary embryos make embryo donation decisions after completing their families or discontinuing use of in vitro fertilization. Recipients of embryos donated for procreative implantation typically plan to transfer fresh or frozen embryos into a prepared uterus in order to facilitate pregnancy and childbirth. Recipients of embryos donated for research typically use them for clinical training, quality improvement research, or human embryonic stem cell research.
The philosophy of biology is a subfield of philosophy of science, which deals with epistemological, metaphysical, and ethical issues in the biological and biomedical sciences. Although philosophers of science and philosophers generally have long been interested in biology, philosophy of biology only emerged as an independent field of philosophy in the 1960s and 1970s, associated with the research of David Hull. Philosophers of science then began paying increasing attention to biology, from the rise of Neodarwinism in the 1930s and 1940s to the discovery of the structure of DNA in 1953 to more recent advances in genetic engineering. Other key ideas include the reduction of all life processes to biochemical reactions, and the incorporation of psychology into a broader neuroscience.
Regenerative medicine deals with the "process of replacing, engineering or regenerating human or animal cells, tissues or organs to restore or establish normal function". This field holds the promise of engineering damaged tissues and organs by stimulating the body's own repair mechanisms to functionally heal previously irreparable tissues or organs.
Dorothy Wolfers Nelkin was an American sociologist of science most noted for her work researching and chronicling interplay between science, technology and the general public. Her work often highlighted the ramifications of unchecked scientific advances and potential threats to privacy and civil liberties. She was the author or co-author of 26 books, including Selling Science: How the Press Covers Science and Technology, The Molecular Gaze: Art in the Genetic Age, and Body Bazaar: The Market for Human Tissue in the Biotechnology Age.
Human oocyte cryopreservation is a procedure to preserve a woman's eggs (oocytes). This technique has been used to enable women to postpone pregnancy to a later date – whether for medical reasons, or for social reasons. Several studies have shown that most infertility problems are due to germ cell deterioration related to aging. The intention of the procedure is that the woman may choose to have the eggs thawed, fertilized, and transferred to the uterus as embryos to facilitate a pregnancy in the future. The procedure's success rate varies depending on the age of the woman, with odds being higher in younger, adult women.
A biobank is a type of biorepository that stores biological samples for use in research. Biobanks have become an important resource in medical research, supporting many types of contemporary research like genomics and personalized medicine.
Cryopreservation or cryoconservation is a process where biological material - cells, tissues, or organs - are frozen to preserve the material for an extended period of time. At low temperatures any cell metabolism which might cause damage to the biological material in question is effectively stopped. Cryopreservation is an effective way to transport biological samples over long distances, store samples for prolonged periods of time, and create a bank of samples for users. Molecules, referred to as cryoprotective agents (CPAs), are added to reduce the osmotic shock and physical stresses cells undergo in the freezing process. Some cryoprotective agents used in research are inspired by plants and animals in nature that have unique cold tolerance to survive harsh winters, including: trees, wood frogs, and tardigrades.
Mitochondrial replacement therapy (MRT), sometimes called mitochondrial donation, is the replacement of mitochondria in one or more cells to prevent or ameliorate disease. MRT originated as a special form of in vitro fertilisation in which some or all of the future baby's mitochondrial DNA (mtDNA) comes from a third party. This technique is used in cases when mothers carry genes for mitochondrial diseases. The therapy is approved for use in the United Kingdom. A second application is to use autologous mitochondria to replace mitochondria in damaged tissue to restore the tissue to a functional state. This has been used in clinical research in the United States to treat cardiac-compromised newborns.
Several authors have used the terms organ gifting and "tissue gifting" to describe processes behind organ and tissue transfers that are not captured by more traditional terms such as donation and transplantation. The concept of "gift of life" in the U.S. refers to the fact that "transplantable organs must be given willingly, unselfishly, and anonymously, and any money that is exchanged is to be perceived as solely for operational costs, but never for the organs themselves". "Organ gifting" is proposed to contrast with organ commodification. The maintenance of a spirit of altruism in this context has been interpreted by some as a mechanism through which the economic relations behind organ/tissue production, distribution, and consumption can be disguised. Organ/tissue gifting differs from commodification in the sense that anonymity and social trust are emphasized to reduce the offer and request of monetary compensation. It is reasoned that the implementation of the gift-giving analogy to organ transactions shows greater respect for the diseased body, honors the donor, and transforms the transaction into a morally acceptable and desirable act that is borne out of voluntarism and altruism.
Eloise "Elo" R. Giblett was a pioneering genetic scientist and hematologist who discovered the first recognized immunodeficiency disease, adenosine deaminase deficiency. Giblett was a Professor of Medicine at the University of Washington in Seattle and Executive Director of the Puget Sound Blood Center in Seattle. The author of over 200 research papers, she also wrote an esteemed textbook on genetic markers, Genetic Markers in Human Blood, published in 1969. She was elected to the National Academy of Sciences in 1980.
Chung Hyung-min is a South Korean biotechnology professor. He was appointed professor at CHA University in 1997 after obtaining his BA, MA and Ph.D degree at Konkuk University.
HIV/AIDS research includes all medical research that attempts to prevent, treat, or cure HIV/AIDS, as well as fundamental research about the nature of HIV as an infectious agent and AIDS as the disease caused by HIV.
Dr. Julie Kent is a Professor of Sociology at the University of the West of England.
Cellular agriculture focuses on the production of agricultural products from cell cultures using a combination of biotechnology, tissue engineering, molecular biology, and synthetic biology to create and design new methods of producing proteins, fats, and tissues that would otherwise come from traditional agriculture. Most of the industry is focused on animal products such as meat, milk, and eggs, produced in cell culture rather than raising and slaughtering farmed livestock which is associated with substantial global problems of detrimental environmental impacts, animal welfare, food security and human health. Cellular agriculture is field of the biobased economy. The most well known cellular agriculture concept is cultured meat.
Andrew Webster (1951–2021) was an English sociologist who was a professor of sociology at the University of York, where he established the Science and Technology Studies research unit. He studied the sociocultural and economic implications of introducing biomedical technologies, including stem cell research and regenerative medicine, into clinical settings.
