Hematopoietic stem-cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood in order to replicate inside of a patient and to produce additional normal blood cells. It may be autologous, allogeneic or syngeneic.
Edward Donnall "Don" Thomas was an American physician, professor emeritus at the University of Washington, and director emeritus of the clinical research division at the Fred Hutchinson Cancer Research Center. In 1990 he shared the Nobel Prize in Physiology or Medicine with Joseph E. Murray for the development of cell and organ transplantation. Thomas and his wife and research partner Dottie Thomas developed bone marrow transplantation as a treatment for leukemia.
Houston Lee Moffitt Cancer Center & Research Institute is a nonprofit cancer treatment and research center located in Tampa, Florida. Established in 1981 by the Florida Legislature, the hospital opened in October 1986 on the University of South Florida's campus. Moffitt is one of two National Cancer Institute-designated Comprehensive Cancer Centers based in Florida. In 2021, U.S. News & World Report ranked Moffitt Cancer Center as a top 30 cancer hospital in the United States.
M Health Fairview University of Minnesota Medical Center (UMMC) previously known as University of Minnesota Medical Center, is a 1700-bed non-profit, tertiary, research and academic medical center located in Minneapolis, Minnesota, servicing the entire region. UMMC is the region's only university-level academic medical center. The hospital is operated by the M Health Fairview Health System and the largest hospital in the system. UMMC is affiliated with the University of Minnesota Medical School. UMMC is also an ACS designated level II trauma center and has a rooftop helipad to handle medevac patients. Attached to the medical center is the Masonic Children's Hospital that treats infants, children, adolescents, and young adults up to the age of 21.
The University of Minnesota Medical School is a medical school at the University of Minnesota. It is a combination of two campuses located in Minneapolis and Duluth, Minnesota.
The National Marrow Donor Program (NMDP) is a nonprofit organization founded in 1986 and based in Minneapolis, Minnesota, that operates the Be The Match Registry of volunteer hematopoietic cell donors and umbilical cord blood units in the United States.
Robert Peter Gale is an American physician and medical researcher. He is known for research in leukemia and other bone marrow disorders.
Transplantable organs and tissues may refer to both organs and tissues that are relatively often transplanted, as well as organs and tissues which are relatively seldom transplanted. In addition to this it may also refer to possible-transplants which are still in the experimental stage.
The Gift of Life Marrow Registry is a public bone marrow and blood stem cell registry headquartered in Boca Raton, Florida. Gift of Life facilitates transplants for children and adults suffering from life-threatening illnesses, including leukemia, lymphoma, other cancers and genetic diseases.
Allen Charles Edward Eaves is the co-founding Director of the Terry Fox Laboratory for Hematology/Oncology Research, which over a 25-year period (1981–2006) he grew into an internationally recognized centre for the study of leukemia and stem cell research. His own research on chronic myelogenous leukemia (CML) has led the way to a new understanding of the disease. As Head of Hematology at the British Columbia Cancer Agency and the University of British Columbia for 18 years (1985–2003) he engineered the building of one of the first and largest bone marrow transplant programs in Canada. In recognition of his research accomplishments and leadership in moving basic science discoveries in stem cell biology into the clinic, he was elected President of the International Society of Cellular Therapy (1995–1997), Treasurer of the Foundation for the Accreditation of Cellular Therapy (1995–2002) and President of the American Society of Blood and Marrow Transplantation (1999–2000). In 2003 he was awarded the prestigious R. M. Taylor Medal by the Canadian Cancer Society and the National Cancer Institute of Canada.
Konstance K. Knox is an American virologist and entrepreneur who founded Coppe Laboratories, Viracor, the Wisconsin Viral Research Group (WVRG) and Viracor's Institute for Viral Pathogenesis (IVP). In 2000, Viracor became the first biotechnology company in the United States to correlate multiple sclerosis with human herpesvirus 6 (HHV-6).
John M. Goldman was a British haematologist, oncologist and medical researcher. A specialist in chronic myeloid leukaemia, Goldman conducted pioneering research into leukaemia treatment – he was instrumental in the development of bone marrow transplantation as a clinical method, and later in the development of the drug imatinib. He was also a prolific author of scientific papers, was involved with numerous medical charities and had a decades-long surgical career at Hammersmith Hospital, London.
The Binaytara Foundation (BTF) was established in 2007 by Dr. Binay Shah and wife Tara Shah with the goal of promoting health and education in underprivileged societies. The BTF is a Washington State nonprofit organization exempt from taxation pursuant to Section 501(c)(3) of the Internal Revenue Code. BTF has founded multiple programs in underdeveloped and developing countries to improve access to healthcare. Recent accomplishments include building a 25-bed cancer hospital in Nepal in 2018 and breaking ground on their new 200-bed facility in 2022.
Surapol Issaragrisil is medical doctor and professor of medicine at Division of Hematology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University. He is an expert at hematology, bone marrow transplantation, and blood stem cells transplantation.
Mammen Chandy is a former director of Tata Medical Center, Kolkata. Chandy, an alumnus of Christian Medical College,Vellore, is a pioneer in the field of bone marrow transplantation in India. He was involved in setting up the first bone marrow transplantation program in the country at Christian Medical College, Vellore in 1986. In January 2019, Chandy was awarded Padma Shri for his contribution to the field of medicine.
Shimon Slavin is an Israeli professor of medicine. Slavin pioneered the use of immunotherapy mediated by allogeneic donor lymphocytes and innovative methods for stem cell transplantation for the cure of hematological malignancies and solid tumors, and using hematopoietic stem cells for induction of transplantation tolerance to bone marrow and donor allografts.
Martin Körbling is a German-American internist and hematologist, university professor, medical researcher and pioneer of blood stem cell transplantation.
Stephanie J. Lee is an American haematologist and physician scientist who is Professor and Associate Director at the Fred Hutchinson Cancer Research Center. Lee works to improve the lives of blood stem cell transplant and bone marrow patients by better understanding the chronic form of graft-versus-host disease. Lee is the former President of the American Society of Hematology.
Mary M. Horowitz is an American oncologist who specializes in blood and marrow transplants.
Julie Ann Panepinto is an American pediatric hematologist-oncologist and physician-scientist. She specializes in health outcomes research and sickle cell disease. Panepinto became the acting director of the division of blood diseases and resources at the National Heart, Lung, and Blood Institute in 2022. She was a professor of pediatrics and hematology at the Medical College of Wisconsin.
