Related Research Articles
Microfluidics refers to a system that manipulates a small amount of fluids using small channels with sizes ten to hundreds micrometres. It is a multidisciplinary field that involves molecular analysis, molecular biology, and microelectronics. It has practical applications in the design of systems that process low volumes of fluids to achieve multiplexing, automation, and high-throughput screening. Microfluidics emerged in the beginning of the 1980s and is used in the development of inkjet printheads, DNA chips, lab-on-a-chip technology, micro-propulsion, and micro-thermal technologies.
Nanomedicine is the medical application of nanotechnology. Nanomedicine ranges from the medical applications of nanomaterials and biological devices, to nanoelectronic biosensors, and even possible future applications of molecular nanotechnology such as biological machines. Current problems for nanomedicine involve understanding the issues related to toxicity and environmental impact of nanoscale materials.
High throughput biology is the use of automation equipment with classical cell biology techniques to address biological questions that are otherwise unattainable using conventional methods. It may incorporate techniques from optics, chemistry, biology or image analysis to permit rapid, highly parallel research into how cells function, interact with each other and how pathogens exploit them in disease.
Giulio Superti-Furga is an Italian molecular and systems biologist based in Vienna, Austria. He is the Scientific Director of CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, and Professor of Medical Systems Biology at the Medical University of Vienna. In January 2024, he was appointed Chair of EU-LIFE, the alliance of research institutes advocating for excellent research in Europe.
Douglas Hanahan is an American biologist, professor and director emeritus of the Swiss Institute for Experimental Cancer Research at EPFL in Lausanne, Switzerland. He is currently member of the Lausanne branch of the Ludwig Institute.
The Molecular Medicine Partnership Unit is an alliance between the European Molecular Biology Laboratory and the Medical Faculty of the University of Heidelberg. Its primary aim is to uncover the molecular basis of disease and to speed the transformation of biomedical discoveries into personalized medicine strategies.
Ashok Venkitaraman is a British cancer researcher of Indian origin. He is the Director of the Cancer Science Institute of Singapore, a Distinguished Professor of Medicine at the National University of Singapore, and Program Director at A*STAR, Singapore. From 1998 to 2020, he was the inaugural holder of the Ursula Zoellner Professorship of Cancer Research at the University of Cambridge, a Professorial Fellow at Pembroke College, Cambridge, and from 2006 to 2019, was the Director of the Medical Research Council Cancer Unit.
Tobias C. Walther is the chair of the cell biology program at Sloan Kettering Institute in New York City and a professor at Weill Cornell School of Medicine, where he co-directs the Farese and Walther lab. He has been a Howard Hughes Medical Institute investigator since 2015. His primary responsibilities are to provide leadership in research and teaching in the scientific fields of metabolism, membrane biology and lipids.
Droplet-based microfluidics manipulate discrete volumes of fluids in immiscible phases with low Reynolds number and laminar flow regimes. Interest in droplet-based microfluidics systems has been growing substantially in past decades. Microdroplets offer the feasibility of handling miniature volumes of fluids conveniently, provide better mixing, encapsulation, sorting, sensing and are suitable for high throughput experiments. Two immiscible phases used for the droplet based systems are referred to as the continuous phase and dispersed phase.
Microfluidics refers to the flow of fluid in channels or networks with at least one dimension on the micron scale. In open microfluidics, also referred to as open surface microfluidics or open-space microfluidics, at least one boundary confining the fluid flow of a system is removed, exposing the fluid to air or another interface such as a second fluid.
Anindya Dutta is an Indian-born American biochemist and cancer researcher, a Chair of the Department of Genetics at the University of Alabama at Birmingham School of Medicine since 2021, who has served as Chair of the Department of Biochemistry and Molecular Genetics at the University of Virginia School of Medicine in 2011–2021. Dutta's research has focused on the mammalian cell cycle with an emphasis on DNA replication and repair and on noncoding RNAs. He is particularly interested in how de-regulation of these processes promote cancer progression. For his accomplishments he has been elected a Fellow of the American Association for the Advancement of Science, received the Ranbaxy Award in Biomedical Sciences, the Outstanding Investigator Award from the American Society for Investigative Pathology, the Distinguished Scientist Award from the University of Virginia and the Mark Brothers Award from the Indiana University School of Medicine.
Jason S. Lewis is a British radiochemist whose work relates to oncologic therapy and diagnosis. His research focus is a molecular imaging-based program focused on radiopharmaceutical development as well as the study of multimodality small- and biomolecule-based agents and their clinical translation. He has worked on the development of small molecules as well as radiolabeled peptides and antibodies probing the overexpression of receptors and antigens on tumors.
Françoise Gisou van der Goot is a Swiss-Dutch cell biologist. She is a professor and the Vice President for Responsible Transformation at EPFL.
Matthias Lutolf is a bio-engineer and a professor at EPFL where he leads the Laboratory of Stem Cell Bioengineering. He is specialised in biomaterials, and in combining stem cell biology and engineering to develop improved organoid models. In 2021, he became the scientific director for Roche's Institute for Translation Bioengineering in Basel.
Bart Deplancke is a Belgian bio-engineer and researcher. He is a full professor at École Polytechnique Fédérale de Lausanne, where he leads the laboratory of systems biology and genetics.
Pierre Gönczy is a Swiss and Italian cell and developmental biologist. His research focuses on centriole biology and asymmetric cell division. He is currently professor at École Polytechnique Fédérale de Lausanne (EPFL), where he directs the Laboratory of Cell and Developmental Biology.
Didier Trono is a Swiss virologist and a professor at the École Polytechnique Fédérale de Lausanne (EPFL). He is known for his research on virus-host interactions and the development of lentiviral vectors for gene therapy.
Carlotta Guiducci is an Italian bio-engineer. Her research is invested in bio-molecular analysis based on lab-on-a-chip devices. She is an Associate Professor at EPFL and head of the Laboratory of Life Sciences Electronics located at EPFL's Lausanne campus.
Gerardo Turcatti is a Swiss-Uruguayan chemist who specialises in chemical biology and drug discovery. He is a professor at the École Polytechnique Fédérale de Lausanne (EPFL) and director of the Biomolecular Screening Facility at the School of Life Sciences there.
Nicolas H. Thomä is a German researcher, full professor at the EPFL School of Life Sciences and Director of the Paternot Chair for Cancer Research in Lausanne, Switzerland. He is a biochemist and structural biologist and a leading researcher in the fields of ubiquitin ligase biology and DNA repair.
References
- ↑ "Christoph Merten". EPFL.
- ↑ Geneux, Valérie (7 September 2020). "L'EPFL accueille un spécialiste de la microfluidique biomédicale". EPFL.
- ↑ Biology, ©2022 MRC Laboratory of Molecular. "LMB Alumni List". MRC Laboratory of Molecular Biology.
{{cite web}}: CS1 maint: numeric names: authors list (link) - ↑ Geneux, Valérie (7 September 2020). "Expert in Biomedical Microfluidics Joins EPFL". EPFL.
- ↑ "Combi-seq: A leap forward for personalized cancer therapy". Medicalxpress.com.
- ↑ Engineering, School of (26 September 2019). "Nominations of Professors at the School of Engineering". EPFL.
- ↑ "Members". EPFL.
- ↑ "ADJUNCTS". Ludwig Cancer Research.
- ↑ "Microfluidic platform for the best possible cancer therapy". Gesundheitsindustrie BW. 11 December 2023.
- ↑ Geneux, Valérie (25 June 2020). "Christoph Merten Co-Awarded a Major SNSF Sinergia Grant". EPFL.
- ↑ Mathur, L.; Szalai, B.; Du, N. H.; Utharala, R.; Ballinger, M.; Landry, J. J. M.; Ryckelynck, M.; Benes, V.; Saez-Rodriguez, J.; Merten, C. A. (1 August 2022). "Combi-seq for multiplexed transcriptome-based profiling of drug combinations using deterministic barcoding in single-cell droplets". Nature Communications. 13 (1): 4450. Bibcode:2022NatCo..13.4450M. doi:10.1038/s41467-022-32197-0. PMC 9343464 . PMID 35915108.
External links
- Christoph Merten publications indexed by Google Scholar
Professor Christoph Merten | |
|---|---|
 Christoph Merten in 2021 | |
| Born | |
| Nationality | German |
| Occupation(s) | Professor and entrepreneur |
| Known for | Development of droplet-based microfluidic technologies for biomedical applications |
| Academic background | |
| Alma mater | Goethe University of Frankfurt |
| Doctoral advisor | Christian Buchholz |
| Authority control databases: Academics |
|---|
