Christos Socrates Mantzoros

Christos Socrates Mantzoros
Born	Nafplio, Greece
Alma mater	Harvard Medical School (MS) Harvard T.H. Chan School of Public Health (MS) University of Athens Medical School (DSc) University of Athens Medical School (MD)
Occupations	Medical doctor and Professor at Harvard Medical School
Known for	Leptin, Adiponectin
Awards	Endocrine Society's Outstanding Scholarly Physician Laureate Award (2025) Gerald Reaven, Distinguished Leader in Insulin Resistance Award (2022) American Society of Nutrition E.V. McCollum Award (2020) Endocrine Society's Outstanding Clinical Investigator Award (2018)
Scientific career
Fields	Endocrinology, Diabetes, Metabolism
Institutions	Harvard Medical School, Beth Israel Deaconess Medical Center
Website	www.bidmc.org/research/research-by-department/medicine/endocrinology/laboratories/mantzoros-lab

Christos Socrates Mantzoros is a Greek-born American internist-endocrinologist, teacher, and researcher. He is a professor of medicine at Harvard Medical School and an adjunct professor at Boston University School of Medicine. In the past he has also served as a professor at the Harvard T.H. Chan School of Public Health.

He is board certified in internal medicine and endocrinology & metabolism in both Europe and the United States and serves as the chief of endocrinology, diabetes, and metabolism at the VA Boston Healthcare System. He is also the founding director of human nutrition at Beth Israel Deaconess Medical Center (BIDMC), Harvard Medical School and editor-in-chief of the journal Metabolism: Clinical and Experimental . ^[1]

Mantzoros has served as a board member on the Hellenic College Holy Cross as well as the ALBA Graduate Business School of the American College of Greece board of trustees. ^[2]

Research

Mantzoros researches topics such as human physiology and molecular biology, observational epidemiology studies, and clinical trials treating obesity, diabetes, and other human metabolic diseases. ^[3] Mantzoros is known for his work on leptin, adiponectin, and the proglucagon family of molecules, as well as the relationship between insulin-like growth factors (IGFs) and cancer. ^[3] Leptin has been approved by the United States Food and Drug Administration (FDA) for treating lipodystrophy and severe insulin resistance accompanied by hyperglycemia and hyperlipidemia. ^[3]

His publications include two books and more than 1100 scientific papers. ^[4] In addition to this he has run over 135 clinical trials. ^[4]

Other ventures

Mantzoros heads Mantzoros Consulting, LLC. In 2005, he co-founded Intekrin, Inc., which was later acquired by and merged with Coherus, Inc. ^[5]

Teaching and mentoring

Mantzoros teaches at Harvard Medical School and Boston University School of Medicine where he has mentored more than 200 scientists. ^[6]

Mantzoros teaches pro bono biomedical ethics at the Hellenic College and Holy Cross School of Theology^{[ citation needed ]}, serving on the Archdiocesan Advisory Council on Bioethics, and serving on the Hellenic College Holy Cross ^{[ citation needed ]}, as well as the ALBA Graduate Business School of the American College of Greece board of trustees. ^[2]

Awards

Mantzoros has received the following awards:

• 2025 Celia Carrión Pérez de Tudela Award in Lipodystrophy Research ^[7]

• 2025 Endocrine Society's Outstanding Scholarly Physician Laureate Award ^[8]

• 2021 Korean Society of Nutrition Award co-administered with the American Society for Nutrition ^[9]

• 2020 Gerald Reaven Distinguished Leader in Insulin Resistance Award ^[10]

• 2020 American Society for Nutrition E.V. McCollum Award ^[11]

• 2018 American Society for Nutrition Robert H. Herman Research Award ^[12]

• 2018 European Society of Endocrinology Geoffrey Harris Award ^[13]

• 2018 Endocrine Society's Outstanding Clinical Investigator Award ^[14]

• 2017 Obesity Society TOPS Award ^[15]

Other (selected) awards include:

• 2011 Berson Award Lecture by the American Physiological Society (FASEB) ^[16]

• 2008 Outstanding Investigator Award by the American Federation of Medical Research ^[17]

• 2008 Hygeia Award by the New England Hellenic Medical and Dental Association ^{[ citation needed ]}

• 2007 BIDMC and Harvard Medical School award for Excellence in Mentoring ^{[ citation needed ]}

• 2007 Election to American Society for Clinical Investigation (ASCI) ^[18]

• 2006 Frontiers in Science Award by the American Association of Clinical Endocrinology ^[19]

• 2006 Novartis Award in Diabetes and Metabolic Diseases by the American Diabetes Association ^[20]

• 2006 Lilly Award by the North American Association for the Study of Obesity (the Obesity Society) ^[21]

• 2006 American Society for Reproductive Medicine William C. Andrews Wyeth Endowed Lectureship ^{[ citation needed ]}

• 2006 Mead Johnson Award by the American Society for Nutrition ^[22]

• 2006 HypoCCS Award in Paris, France ^[23]

• 2006 Wilhelm Friedrich Bessel Award by the Humboldt Foundation of Germany ^[24]

References

1. "Christos Mantzoros | Chobanian & Avedisian School of Medicine". www.bumc.bu.edu. Retrieved 2025-07-19.
2. "Governance". ALBA Graduate Business School. Retrieved 22 November 2025.
3. "Christos Mantzoros, MD, DSc, h.c. mult. PhD".
4. "Christos Mantzoros | Chobanian & Avedisian School of Medicine". www.bumc.bu.edu. Retrieved 2025-12-05.
5. "Coherus BioSciences - A Biosimilar Therapeutics Developer".
6. "Endocrinology ICONS - Endocrine News" (PDF).
7. "XIII Simposio Internacional de Lipodistrofias – Entrega del Premio Celia Carrión Pérez de Tudela". AELIP. Asociación Española de Lipodistrofias. 22 November 2025. Retrieved 22 November 2025.
8. "2025 Laureate Award Recipients". Endocrine Society. Endocrine Society. 19 August 2024. Retrieved 22 November 2025.
9. "ASN Awards – Prior Recipients" (PDF). American Society for Nutrition. American Society for Nutrition. Retrieved 22 November 2025.
10. "19th Annual WCIRDC Conference Kicks Off December 2 in Los Angeles". Healio Endocrinology. Healio. Retrieved 22 November 2025.
11. "ASN Foundation Past Award Honorees". American Society for Nutrition. American Society for Nutrition. Retrieved 22 November 2025.
12. "19th Annual WCIRDC Conference Kicks Off December 2 in Los Angeles". Healio Endocrinology. Healio. Retrieved 22 November 2025.
13. "Geoffrey Harris Award – Previous Winners". European Society of Endocrinology. ESE. Retrieved 22 November 2025.
14. "Christos Mantzoros Recognized for Groundbreaking Obesity Research". Beth Israel Deaconess Medical Center. BIDMC. Retrieved 22 November 2025.
15. "The Obesity Society Award Honorees Archive". Obesity Society. Obesity Society. Retrieved 22 November 2025.
16. "Berson Award Lecture – APS". American Physiological Society. APS / FASEB. Retrieved 22 November 2025.
17. "AFMR Outstanding Investigator Award Recipients". AFMR. American Federation of Medical Research. Retrieved 22 November 2025.
18. "ASCI Member Profile – Christos Mantzoros". ASCI. American Society for Clinical Investigation. Retrieved 22 November 2025.
19. "AACE Past Award Recipients". AACE. American Association of Clinical Endocrinology. Retrieved 22 November 2025.
20. "Novartis Award in Diabetes and Metabolic Diseases – ADA". American Diabetes Association. ADA. Retrieved 22 November 2025.
21. "The Obesity Society Award Honorees Archive". Obesity Society. Obesity Society. Retrieved 22 November 2025.
22. "ASN Awards – Prior Recipients" (PDF). ASN. American Society for Nutrition. Retrieved 22 November 2025.
23. "HypoCCS Award 2006". KISTI ScienceOn. KISTI. Retrieved 22 November 2025.
24. "Wilhelm Friedrich Bessel Award – Christos Mantzoros". Humboldt Foundation. Humboldt Foundation. Retrieved 22 November 2025.