CLDN25 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | CLDN25 , claudin 25 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | HomoloGene: 19476; GeneCards: CLDN25; OMA:CLDN25 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Claudin 25 is a protein that in humans is encoded by the CLDN25 gene. [3]
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. [provided by RefSeq, Jun 2010].
Claudin-1 is a protein that in humans is encoded by the CLDN1 gene. It belongs to the group of claudins.
Claudin 4, also known as CLDN4, is a protein which in humans is encoded by the CLDN4 gene. It belongs to the group of claudins.
Claudin-5 is a protein that in humans is encoded by the CLDN5 gene. It belongs to the group of claudins.
Claudin 3, also known as CLDN3, is a protein which in humans is encoded by the CLDN3 gene. It is a member of the claudin protein family.
Claudin-7 is a protein that in humans is encoded by the CLDN7 gene. It belongs to the group of claudins.
Claudin-6 is a protein that in humans is encoded by the CLDN6 gene. It belongs to the group of claudins. The knockout mice of mouse homolog exhibit no phenotype, indicating that claudin-6 is dispensable for normal development and homeostasis.
Claudin-12 is a protein that in humans is encoded by the CLDN12 gene. It belongs to the group of claudins.
Claudin-8 is a protein that in humans is encoded by the CLDN8 gene. It belongs to the group of claudins.
Claudin-11 is a protein that in humans is encoded by the CLDN11 gene. It belongs to the group of claudins and was the first member of the family to be knocked out in mice, thereby demonstrating the central role of claudins for intramembranous strands observed in freeze-fracture images.
Myotubularin-related protein 3 is a protein that in humans is encoded by the MTMR3 gene.
Claudin-16 is a protein that in humans is encoded by the CLDN16 gene. It belongs to the group of claudins.
Claudin-17 is a protein that in humans is encoded by the CLDN17 gene. It belongs to the group of claudins; claudins are cell-cell junction proteins that keep that maintains cell- and tissue-barrier function. It forms anion-selective paracellular channels and is localized mainly in kidney proximal tubules.
Claudin-10 is a protein that in humans is encoded by the CLDN10 gene. It belongs to the group of claudins.
Claudin-15 is a protein that in humans is encoded by the CLDN15 gene. It belongs to the group of claudins. Among its related pathways are Blood-Brain Barrier and Immune Cell Transmigration: VCAM-1/CD106 Signaling Pathways and Tight junction. GO annotations related to this gene include identical protein binding and structural molecule activity. An important paralog of this gene is CLDN10.
Claudin-19 is a protein that in humans is encoded by the CLDN19 gene. It belongs to the group of claudins. Claudin-19 has been implicated in magnesium transport.
Claudin-20 is a protein that in humans is encoded by the CLDN20 gene. It belongs to the group of claudins.
Claudin-18 is a protein that in humans is encoded by the CLDN18 gene. It belongs to the group of claudins.
Tight junction protein ZO-3 is a protein that in humans is encoded by the TJP3 gene.
Claudin-22 is a protein that in humans is encoded by the CLDN22 gene. It belongs to the group of claudins.
Mab-21-like 2 is a protein that in humans is encoded by the MAB21L2 gene.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.