Lassa fever, also known as Lassa hemorrhagic fever, is a type of viral hemorrhagic fever caused by the Lassa virus. Many of those infected by the virus do not develop symptoms. When symptoms occur they typically include fever, weakness, headaches, vomiting, and muscle pains. Less commonly there may be bleeding from the mouth or gastrointestinal tract. The risk of death once infected is about one percent and frequently occurs within two weeks of the onset of symptoms. Of those who survive, about a quarter have hearing loss, which improves within three months in about half of these cases.
Marburg virus disease is a viral hemorrhagic fever in human and non-human primates caused by either of the two Marburgviruses: Marburg virus (MARV) and Ravn virus (RAVV). Its clinical symptoms are very similar to those of Ebola virus disease (EVD).
Tropical diseases are diseases that are prevalent in or unique to tropical and subtropical regions. The diseases are less prevalent in temperate climates, due in part to the occurrence of a cold season, which controls the insect population by forcing hibernation. However, many were present in northern Europe and northern America in the 17th and 18th centuries before modern understanding of disease causation. The initial impetus for tropical medicine was to protect the health of colonial settlers, notably in India under the British Raj. Insects such as mosquitoes and flies are by far the most common disease carrier, or vector. These insects may carry a parasite, bacterium or virus that is infectious to humans and animals. Most often disease is transmitted by an insect bite, which causes transmission of the infectious agent through subcutaneous blood exchange. Vaccines are not available for most of the diseases listed here, and many do not have cures.
The Royal Free Hospital is a major teaching hospital in the Hampstead area of the London Borough of Camden. The hospital is part of the Royal Free London NHS Foundation Trust, which also runs services at Barnet Hospital, Chase Farm Hospital and a number of other sites. The trust is a founder member of the UCLPartners academic health science centre.
Lassa mammarenavirus (LASV) is an arenavirus that causes Lassa hemorrhagic fever, a type of viral hemorrhagic fever (VHF), in humans and other primates. Lassa mammarenavirus is an emerging virus and a select agent, requiring Biosafety Level 4-equivalent containment. It is endemic in West African countries, especially Sierra Leone, the Republic of Guinea, Nigeria, and Liberia, where the annual incidence of infection is between 300,000 and 500,000 cases, resulting in 5,000 deaths per year.
Fortis Green is a ward in the extreme northwestern corner of the Borough of Haringey, north London. It is also the name of the road that runs between Muswell Hill and East Finchley which forms part of the A504.
Viral hemorrhagic fevers (VHFs) are a diverse group of animal and human illnesses. VHFs may be caused by five distinct families of RNA viruses: the families Filoviridae, Flaviviridae, Rhabdoviridae, and several member families of the Bunyavirales order such as Arenaviridae, and Hantaviridae. All types of VHF are characterized by fever and bleeding disorders and all can progress to high fever, shock and death in many cases. Some of the VHF agents cause relatively mild illnesses, such as the Scandinavian nephropathia epidemica, while others, such as Ebola virus, can cause severe, life-threatening disease.
Clarence James Peters, Jr is a physician, field virologist and former U.S. Army colonel. He is noted for his efforts in trying to stem epidemics of exotic infectious diseases such as the Ebola virus, Hanta virus and Rift Valley fever (RVF). He is an eminent authority on the virology, pathogenesis and epidemiology of hemorrhagic fever viruses.
Lujo is a bisegmented RNA virus—a member of the family Arenaviridae—and a known cause of viral hemorrhagic fever (VHF) in humans. Its name was suggested by the Special Pathogens Unit of the National Institute for Communicable Diseases of the National Health Laboratory Service (NICD-NHLS) by using the first two letters of the names of the cities involved in the 2008 outbreak of the disease, Lusaka (Zambia) and Johannesburg. It is the second pathogenic Arenavirus to be described from the African continent—the first being Lassa virus—and since 2012 has been classed as a "Select Agent" under U.S. law.
Aniru Sahib Sahib Conteh was a Sierra Leonean physician and expert on the clinical treatment of Lassa fever, a viral hemorrhagic fever endemic to West Africa caused by the Lassa virus. Conteh studied medicine at the University of Ibadan in Nigeria and taught at Ibadan Teaching Hospital. He later returned to Sierra Leone where he joined the Centers for Disease Control and Prevention (CDC) Lassa fever program at Nixon Methodist Hospital in Segbwema, first as superintendent and then as clinical director.
Sheik Umar Khan was the chief Sierra Leonean doctor attempting to curb the country's Ebola outbreak in 2014.
An Ebola virus epidemic in Sierra Leone occurred in 2014, along with the neighbouring countries of Guinea and Liberia. At the time it was discovered, it was thought that Ebola virus was not endemic to Sierra Leone or to the West African region and that the epidemic represented the first time the virus was discovered there. However, US researchers pointed to lab samples used for Lassa fever testing to suggest that Ebola had been in Sierra Leone as early as 2006.
Ebola virus disease in the United Kingdom and Ireland has occurred rarely in four cases to date, namely three health workers returning from treating victims of the Ebola virus epidemic in West Africa in 2014 and 2015, and a single case in 1976, when a laboratory technician contracted the disease in a needlestick injury while handling samples from Africa. All cases recovered. As of 2023, no domestic transmission of Ebola has occurred in the United Kingdom or Ireland.
Pauline Cafferkey is a Scottish nurse and aid worker who contracted Ebola virus disease in 2014 while working in Sierra Leone as part of the medical aid effort during the West African Ebola virus epidemic. She survived the illness.
A fever hospital or isolation hospital is a hospital for infectious diseases such as Scarlet fever, Tuberculosis, Lassa fever and Smallpox. Their purpose is to treat affected people while isolating them from the general population. Early examples included the Liverpool Fever Hospital (1801) and the London Fever Hospital (1802). Other examples occurred elsewhere in the British Isles and India.
Jordi Casals i Ariet was a Catalan physician and epidemiologist.
In August–November 1976, an outbreak of Ebola virus disease occurred in Zaire. The first recorded case was from Yambuku, a small village in Mongala District, 1,098 kilometres (682 mi) northeast of the capital city of Kinshasa.
The Edinburgh City Hospital was a hospital in Colinton, Edinburgh, opened in 1903 for the treatment of infectious diseases. As the pattern of infectious disease changed, the need for in-patients facilities to treat them diminished. While still remaining the regional centre for infectious disease, in the latter half of the 20th century the hospital facilities diversified with specialist units established for respiratory disease, ear, nose and throat surgery, maxillo-facial surgery, care of the elderly and latterly HIV/AIDS. The hospital closed in 1999 and was redeveloped as residential housing, known as Greenbank Village.
COVID-19 hospital is a general name given to clinical institutions that provide medical treatment to Coronavirus Disease 2019 (COVID-19) infected patients. According to the World Health Organisation (WHO)'s COVID-19 regulations, it is critical to distribute COVID-19 patients to different medical institutions based on their severity of symptoms and the medical resource availability in different geographical regions. It is recommended by the WHO to distribute patients with the most severe symptoms to the most equipped, COVID-19 focused hospitals, then patients with less severe symptoms to local institutions and lastly, patients with light symptoms to temporary COVID-19 establishments for appropriate isolation and monitoring of disease progression. Countries, like China, Germany, Russia, the United Kingdom and the United States have established their distinctive COVID-19 clinical set-ups based on the general WHO guidelines. Future pandemic protocols have also been adapted based on handling COVID-19 on a national and global scale.
