DDX52

DDX52
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3DKP
Identifiers
Aliases	DDX52 , HUSSY19, ROK1, DEAD-box helicase 52, DExD-box helicase 52
External IDs	OMIM: 612500 MGI: 1925644 HomoloGene: 5093 GeneCards: DDX52
Gene location (Human) Chr. Chromosome 17 (human) [1] Band 17q12 Start 37,609,739 bp [1] End 37,643,446 bp [1]
Gene location (Mouse) Chr. Chromosome 11 (mouse) [2] Band 11|11 C Start 83,832,888 bp [2] End 83,853,914 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve endometrium ganglionic eminence islet of Langerhans rectum smooth muscle tissue Achilles tendon thymus corpus callosum duodenum Top expressed in spermatocyte primitive streak morula medullary collecting duct abdominal wall otic placode vas deferens maxillary prominence dermis thymus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding hydrolase activity ATP binding helicase activity nucleic acid binding RNA binding Cellular component membrane nucleoplasm nucleus nucleolus cytoplasm Biological process RNA secondary structure unwinding rRNA processing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 11056 78394 Ensembl ENSG00000277594 ENSG00000278053 ENSMUSG00000020677 UniProt Q9Y2R4 Q8K301 RefSeq (mRNA) NM_001291476 NM_007010 NM_152300 NM_030096 RefSeq (protein) NP_001278405 NP_008941 NP_084372 Location (UCSC) Chr 17: 37.61 – 37.64 Mb Chr 11: 83.83 – 83.85 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Probable ATP-dependent RNA helicase DDX52 is an enzyme that in humans is encoded by the DDX52 gene. ^{[5] [6]}

References

1. ENSG00000278053 GRCh38: Ensembl release 89: ENSG00000277594, ENSG00000278053 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000020677 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Stanchi F, Bertocco E, Toppo S, Dioguardi R, Simionati B, Cannata N, Zimbello R, Lanfranchi G, Valle G (Jan 2001). "Characterization of 16 novel human genes showing high similarity to yeast sequences". Yeast. 18 (1): 69–80. doi:10.1002/1097-0061(200101)18:1<69::AID-YEA647>3.0.CO;2-H. PMID   11124703. S2CID   21397515.
6. "Entrez Gene: DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52".

Further reading

• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC   1356129 . PMID   16344560.
• Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID   15635413. S2CID   4344740.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC   133617 . PMID   12429849.
• Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. doi: 10.1016/S0960-9822(01)00650-9 . PMID   11790298. S2CID   14132033.