DEFA1B

DEFA1B
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 2KHT, 2PM1, 3GNY, 3H6C, 3HJ2, 3HJD, 3LO1, 3LO2, 3LO4, 3LO6, 3LO9, 3LOE, 3LVX, 4DU0, 4LB1, 4LB7, 4LBB, 4LBF
Identifiers
Aliases	DEFA1B , HNP-1, HP-1, HP1, defensin alpha 1B
External IDs	HomoloGene: 128756; GeneCards: DEFA1B; OMA:DEFA1B - orthologs
Gene location (Human) Chr. Chromosome 8 (human) [1] Band 8p23.1 Start 6,996,766 bp [1] End 6,999,198 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in monocyte granulocyte right lung spleen bone marrow blood bone marrow cells upper lobe of left lung placenta right lobe of liver n/a More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 728358 n/a Ensembl ENSG00000240247 ENSG00000285176 n/a UniProt P59665 n/a RefSeq (mRNA) NM_001302265 NM_001042500 n/a RefSeq (protein) NP_001035965 NP_001289194 n/a Location (UCSC) Chr 8: 7 – 7 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Defensin, alpha 1B a human protein that is encoded by the DEFA1B gene. ^[3]

See also

• defensin

References

1. ENSG00000285176 GRCh38: Ensembl release 89: ENSG00000240247, ENSG00000285176 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: defensin".

Further reading

• Kocsis AK, Ocsovszky I, Tiszlavicz L, et al. (2009). "Helicobacter pylori induces the release of alpha-defensin by human granulocytes". Inflamm. Res. 58 (5): 241–7. doi:10.1007/s00011-008-8100-z. PMID   19169650. S2CID   29257427.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Aldred PM, Hollox EJ, Armour JA (2005). "Copy number polymorphism and expression level variation of the human alpha-defensin genes DEFA1 and DEFA3". Hum. Mol. Genet. 14 (14): 2045–52. doi: 10.1093/hmg/ddi209 . PMID   15944200.

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human Neutrophil defensin 1 (DEFA1B)