DEFB118

DEFB118
Identifiers
Aliases	DEFB118 , C20orf63, DEFB-18, ESC42, ESP13.6, defensin beta 118
External IDs	OMIM: 607650; HomoloGene: 89041; GeneCards: DEFB118; OMA:DEFB118 - orthologs
Gene location (Human) Chr. Chromosome 20 (human) [1] Band 20q11.21 Start 31,368,601 bp [1] End 31,373,923 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in corpus epididymis caput epididymis tail of epididymis fallopian tube gonad testicle n/a More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 117285 n/a Ensembl ENSG00000131068 n/a UniProt Q96PH6 n/a RefSeq (mRNA) NM_054112 n/a RefSeq (protein) NP_473453 n/a Location (UCSC) Chr 20: 31.37 – 31.37 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Beta-defensin 118 is a protein that in humans is encoded by the DEFB118 gene. ^{[3] [4] [5]}

References

1. GRCh38: Ensembl release 89: ENSG00000131068 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. Liu Q, Hamil KG, Sivashanmugam P, Grossman G, Soundararajan R, Rao AJ, Richardson RT, Zhang YL, O'Rand MG, Petrusz P, French FS, Hall SH (Oct 2001). "Primate epididymis-specific proteins: characterization of ESC42, a novel protein containing a trefoil-like motif in monkey and human". Endocrinology. 142 (10): 4529–39. doi:10.1210/endo.142.10.8422. PMID   11564719. S2CID   10283278.
4. Yenugu S, Hamil KG, Radhakrishnan Y, French FS, Hall SH (Jul 2004). "The androgen-regulated epididymal sperm-binding protein, human beta-defensin 118 (DEFB118) (formerly ESC42), is an antimicrobial beta-defensin". Endocrinology. 145 (7): 3165–73. doi: 10.1210/en.2003-1698 . PMID   15033915.
5. "Entrez Gene: DEFB118 defensin, beta 118".

Further reading

• van Wetering S, Sterk PJ, Rabe KF, Hiemstra PS (Dec 1999). "Defensins: key players or bystanders in infection, injury, and repair in the lung?". The Journal of Allergy and Clinical Immunology. 104 (6): 1131–8. doi: 10.1016/S0091-6749(99)70004-7 . PMID   10588992.
• Kao CY, Chen Y, Zhao YH, Wu R (Jul 2003). "ORFeome-based search of airway epithelial cell-specific novel human [beta]-defensin genes". American Journal of Respiratory Cell and Molecular Biology. 29 (1): 71–80. CiteSeerX   10.1.1.108.7808 . doi:10.1165/rcmb.2002-0205OC. PMID   12600824.
• Schutte BC, Mitros JP, Bartlett JA, Walters JD, Jia HP, Welsh MJ, Casavant TL, McCray PB (Feb 2002). "Discovery of five conserved beta -defensin gene clusters using a computational search strategy". Proceedings of the National Academy of Sciences of the United States of America. 99 (4): 2129–33. Bibcode:2002PNAS...99.2129S. doi: 10.1073/pnas.042692699 . PMC   122330 . PMID   11854508.