Heroin, also known as diacetylmorphine and diamorphine among other names, is a morphinan opioid substance synthesized from the dried latex of the Papaver somniferum plant and is mainly used as a recreational drug for its euphoric effects. Medical-grade diamorphine is used as a pure hydrochloride salt. Various white and brown powders sold illegally around the world as heroin are routinely diluted with cutting agents. Black tar heroin is a variable admixture of morphine derivatives—predominantly 6-MAM (6-monoacetylmorphine), which is the result of crude acetylation during clandestine production of street heroin. Heroin is used medically in several countries to relieve pain, such as during childbirth or a heart attack, as well as in opioid replacement therapy.
The Harrison Narcotics Tax Act was a United States federal law that regulated and taxed the production, importation, and distribution of opiates and coca products. The act was proposed by Representative Francis Burton Harrison of New York and was approved on December 17, 1914.
Morphine is a strong opiate that is found naturally in opium, a dark brown resin produced by drying the latex of opium poppies. It is mainly used as an analgesic. There are numerous methods used to administer morphine: oral; sublingual; via inhalation; injection into a muscle, injection under the skin, or injection into the spinal cord area; transdermal; or via rectal suppository. It acts directly on the central nervous system (CNS) to induce analgesia and alter perception and emotional response to pain. Physical and psychological dependence and tolerance may develop with repeated administration. It can be taken for both acute pain and chronic pain and is frequently used for pain from myocardial infarction, kidney stones, and during labor. Its maximum effect is reached after about 20 minutes when administered intravenously and 60 minutes when administered by mouth, while the duration of its effect is 3–7 hours. Long-acting formulations of morphine are available as MS-Contin, Kadian, and other brand names as well as generically.
Opium is dried latex obtained from the seed capsules of the opium poppy Papaver somniferum. Approximately 12 percent of opium is made up of the analgesic alkaloid morphine, which is processed chemically to produce heroin and other synthetic opioids for medicinal use and for the illegal drug trade. The latex also contains the closely related opiates codeine and thebaine, and non-analgesic alkaloids such as papaverine and noscapine. The traditional, labor-intensive method of obtaining the latex is to scratch ("score") the immature seed pods (fruits) by hand; the latex leaks out and dries to a sticky yellowish residue that is later scraped off and dehydrated. The word meconium historically referred to related, weaker preparations made from other parts of the opium poppy or different species of poppies.
The term narcotic originally referred medically to any psychoactive compound with numbing or paralyzing properties. In the United States, it has since become associated with opiates and opioids, commonly morphine and heroin, as well as derivatives of many of the compounds found within raw opium latex. The primary three are morphine, codeine, and thebaine.
The prohibition of drugs through sumptuary legislation or religious law is a common means of attempting to prevent the recreational use of certain intoxicating substances.
Speedball, powerball, or over and under, is the polydrug mixture of a stimulant with a depressant, usually an opioid. Common stimulants and depressants used for recreational drug use include cocaine or amphetamine with heroin, morphine, and/or fentanyl that may be taken intravenously or by nasal insufflation.
Rat Park was a series of studies into drug addiction conducted in the late 1970s and published between 1978 and 1981 by Canadian psychologist Bruce K. Alexander and his colleagues at Simon Fraser University in British Columbia, Canada.
The LaGuardia Committee was the first in-depth study into the effects of smoking cannabis in the United States. An earlier study, the Indian Hemp Drugs Commission, was conducted by the colonial authorities in British India in 1893–94. The reports systematically contradicted claims made by the U.S. Treasury Department that smoking marijuana results in insanity, deteriorates physical and mental health, assists in criminal behavior and juvenile delinquency, is physically addictive, and is a "gateway" drug to more dangerous drugs.
Drug injection is a method of introducing a drug into the bloodstream via a hollow hypodermic needle, which is pierced through the skin into the body. Intravenous therapy, a form of drug injection, is universally practiced in modernized medical care. As of 2004, there were 13.2 million people worldwide who self-administered injection drugs outside of medical supervision, of which 22% are from developed countries.
The drug policy in the United States is the activity of the federal government relating to the regulation of drugs. Starting in the early 1900s, the United States government began enforcing drug policies. These policies criminalized drugs such as opium, morphine, heroin, and cocaine outside of medical use. The drug policies put into place are enforced by the Food and Drug Administration and the Drug Enforcement Administration. Classification of Drugs are defined and enforced using the Controlled Substance Act, which lists different drugs into their respective substances based on its potential of abuse and potential for medical use. Four different categories of drugs are Alcohol, Cannabis, Opioids, and Stimulants.
A drug policy is the policy regarding the control and regulation of psychoactive substances, particularly those that are addictive or cause physical and mental dependence. While drug policies are generally implemented by governments, entities at all levels may have specific policies related to drugs.
Drugs considered addictive or dangerous in the United Kingdom are called "controlled substances" and regulated by law. Until 1964 the medical treatment of dependent drug users was separated from the punishment of unregulated use and supply. Under this policy drug use remained low; there was relatively little recreational use and few dependent users, who were prescribed drugs by their doctors as part of their treatment. From 1964 drug use was decreasingly criminalised, with the framework still in place as of 2014 largely determined by the Misuse of Drugs Act.
The Interdepartmental Committee on Drug Addiction, commonly called the Brain Committee after its chairman Sir Russell Brain, was created by the Home Office in 1958 to consider issues related to drugs and drug addiction in the United Kingdom. The committee explored whether or not certain drugs should be considered addictive or habit-forming; examined whether there was a medical need to provide special, including institutional, treatment outside the resources already available, for persons addicted to drugs; and made recommendations, including proposals for administrative measures, to the Minister of Health and the Secretary of State for Scotland.
In 1924, following concerns about the treatment of addicts by doctors, James Smith Whitaker suggested to the Home Office who suggested to the Ministry of Health Departmental Committee on Morphine and Heroin Addiction be formed under the chairmanship of Sir Humphry Rolleston to "... consider and advise as to the circumstances, if any, in which the supply of morphine and heroin to persons suffering from addiction to those drugs may be regarded as medically advisable, and as to the precautions which it is desirable that medical practitioners administering or prescribing morphine or heroin should adopt for the avoidance of abuse, and to suggest any administrative measures that seem expedient for securing observance of such precautions". The committee is usually referred to as the Rolleston Committee.
The Home Office Drugs Inspectorate was a branch of the British Home Office. It was formed in 1934, although its origins can be traced back to 1916, and one other reference speaks of June 1922. It was disbanded in 2007.
John Petro, called 'The Junkie's Friend', was Polish and came to the UK in 1916. During the War he worked as a doctor with Alexander Fleming giving penicillin to the troops. In 1966, having been run down by a car, he was unable to work and soon got into debt. He was made bankrupt in 1967. He said he was unable to find premises, so he gave out prescriptions for drugs anywhere. He was thought to be selling prescriptions to addicts, which led to him being nicknamed the 'Junkie's Friend'. After pleading guilty at Marylebone Magistrates Court, in February 1968, he was fined £1700.
The Dangerous Drugs Regulations 1968 determined the consultants who could prescribe, or treat addicts either in psychiatric hospitals or drug dependency units. Other medical staff, if supervised by the consultants within the hospitals, would also be able to obtain licences. Doctors working outside the NHS would be considered if their organisations had similar facilities to the DDUs. Doctors who disobeyed these regulations might have their permissions to supply rescinded. In fact only the treatment centers were allowed to supply.
Cocaine is the second most popular illegal recreational drug in the United States behind cannabis, and the U.S. is the world's largest consumer of cocaine. In 2020, Oregon became the first U.S. state to decriminalize cocaine.
In the United States, the opioid epidemic is an extensive, ongoing overuse of opioid medications, both from medical prescriptions and illegal sources. The epidemic began in the United States in the late 1990s, according to the Centers for Disease Control and Prevention (CDC), when opioids were increasingly prescribed for pain management, resulting in a rise in overall opioid use throughout subsequent years. The great majority of Americans who use prescription opioids do not believe that they are misusing them.
