David Callaway

Last updated
David J. E. Callaway
David J. E. Callaway.jpg
David J. E. Callaway
Alma mater University of Washington; Caltech
Scientific career
Fields Biological physics
Institutions New York University School of Medicine
Thesis QCD and Weak Asymmetries in Lepton Pair Production  (1981)
Doctoral advisor Ernest M. Henley

David James Edward Callaway is a biological nanophysicist in the New York University School of Medicine, where he is professor and laboratory director. He was trained as a theoretical physicist by Richard Feynman, Kip Thorne, and Cosmas Zachos, and was previously an associate professor at the Rockefeller University after positions at CERN and Los Alamos National Laboratory. Callaway's laboratory discovered potential therapeutics for Alzheimer's disease based upon apomorphine [1] after an earlier paper of his developed models of Alzheimer amyloid formation. [2] He has also initiated the study of protein domain dynamics [3] by neutron spin echo spectroscopy, providing a way to observe protein nanomachines in motion. [4] [5]

Contents

Previous work includes the invention of the microcanonical ensemble approach to lattice gauge theory with Aneesur Rahman, [6] [7] work on the convexity of the effective potential of quantum field theory, [8] work on Langevin dynamics in quantum field theory with John R. Klauder, [9] a monograph on quantum triviality, [10] constraints on the Higgs boson [11] and papers on black holes [12] and superconductors. [13] His work in these areas is highly cited and notable. [14] [15]

Athletic accomplishments

Everest climbers receive Tengboche blessing. Ginette Harrison, Sir David Hempleman-Adams, David Callaway, Scott McIvor, Lee Nobmann, Brian Blessed. Everestblessings.jpg
Everest climbers receive Tengboche blessing. Ginette Harrison, Sir David Hempleman-Adams, David Callaway, Scott McIvor, Lee Nobmann, Brian Blessed.
Jean-Christophe Lafaille (left) and D J E Callaway at Shishapangma base camp Lafaille.gif
Jean-Christophe Lafaille (left) and D J E Callaway at Shishapangma base camp

Dr Callaway is an avid expedition mountaineer and polar explorer. [16] He was a competitor on the first Eco-Challenge. [17]

Related Research Articles

<span class="mw-page-title-main">Technicolor (physics)</span> Hypothetical model through which W and Z bosons acquire mass

Technicolor theories are models of physics beyond the Standard Model that address electroweak gauge symmetry breaking, the mechanism through which W and Z bosons acquire masses. Early technicolor theories were modelled on quantum chromodynamics (QCD), the "color" theory of the strong nuclear force, which inspired their name.

<span class="mw-page-title-main">Lattice gauge theory</span> Theory of quantum gauge fields on a lattice

In physics, lattice gauge theory is the study of gauge theories on a spacetime that has been discretized into a lattice.

In physics, the Landau pole is the momentum scale at which the coupling constant of a quantum field theory becomes infinite. Such a possibility was pointed out by the physicist Lev Landau and his colleagues in 1954. The fact that couplings depend on the momentum scale is the central idea behind the renormalization group.

<span class="mw-page-title-main">Lattice QCD</span> Quantum chromodynamics on a lattice

Lattice QCD is a well-established non-perturbative approach to solving the quantum chromodynamics (QCD) theory of quarks and gluons. It is a lattice gauge theory formulated on a grid or lattice of points in space and time. When the size of the lattice is taken infinitely large and its sites infinitesimally close to each other, the continuum QCD is recovered.

Hadronization is the process of the formation of hadrons out of quarks and gluons. There are two main branches of hadronization: quark-gluon plasma (QGP) transformation and colour string decay into hadrons. The transformation of quark-gluon plasma into hadrons is studied in lattice QCD numerical simulations, which are explored in relativistic heavy-ion experiments. Quark-gluon plasma hadronization occurred shortly after the Big Bang when the quark–gluon plasma cooled down to the Hagedorn temperature when free quarks and gluons cannot exist. In string breaking new hadrons are forming out of quarks, antiquarks and sometimes gluons, spontaneously created from the vacuum.

In lattice field theory, fermion doubling occurs when naively putting fermionic fields on a lattice, resulting in more fermionic states than expected. For the naively discretized Dirac fermions in Euclidean dimensions, each fermionic field results in identical fermion species, referred to as different tastes of the fermion. The fermion doubling problem is intractably linked to chiral invariance by the Nielsen–Ninomiya theorem. Most strategies used to solve the problem require using modified fermions which reduce to the Dirac fermion only in the continuum limit.

A conformal anomaly, scale anomaly, trace anomaly or Weyl anomaly is an anomaly, i.e. a quantum phenomenon that breaks the conformal symmetry of the classical theory.

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<span class="mw-page-title-main">Bernard Julia</span> French theoretical physicist (born 1952)

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<span class="mw-page-title-main">William A. Bardeen</span> American theoretical physicist

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The eta and eta prime meson are isosinglet mesons made of a mixture of up, down and strange quarks and their antiquarks. The charmed eta meson and bottom eta meson are similar forms of quarkonium; they have the same spin and parity as the (light)
η
defined, but are made of charm quarks and bottom quarks respectively. The top quark is too heavy to form a similar meson, due to its very fast decay.

<span class="mw-page-title-main">Aneesur Rahman</span> Indian physicist

Aneesur Rahman was an Indian-born American physicist who pioneered the application of computational methods to physical systems. His 1964 paper on liquid argon studied a system of 864 argon atoms on a CDC 3600 computer, using a Lennard-Jones potential. His algorithms still form the basis for many codes written today. Moreover, he worked on a wide variety of problems, such as the microcanonical ensemble approach to lattice gauge theory, which he invented with David J E Callaway.

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<span class="mw-page-title-main">Light-front computational methods</span> Technique in computational quantum field theory

The light-front quantization of quantum field theories provides a useful alternative to ordinary equal-time quantization. In particular, it can lead to a relativistic description of bound systems in terms of quantum-mechanical wave functions. The quantization is based on the choice of light-front coordinates, where plays the role of time and the corresponding spatial coordinate is . Here, is the ordinary time, is one Cartesian coordinate, and is the speed of light. The other two Cartesian coordinates, and , are untouched and often called transverse or perpendicular, denoted by symbols of the type . The choice of the frame of reference where the time and -axis are defined can be left unspecified in an exactly soluble relativistic theory, but in practical calculations some choices may be more suitable than others.

Alberto Sirlin was an Argentine theoretical physicist, specializing in particle physics.

<span class="mw-page-title-main">Claude Itzykson</span> French theoretical physicist (1938–1995)

Claude Georges Itzykson, was a French theoretical physicist who worked in quantum field theory and statistical mechanics.

References

  1. Lashuel, H. A.; Hartley, D. M.; Balakhaneh, D.; Aggarwal A.; Teichberg S.; Callaway, D. J. E. (2002). "New class of inhibitors of amyloid-beta fibril formation. Implications for the mechanism of pathogenesis in Alzheimer's disease". J Biol Chem . 277 (45): 42881–42890. doi: 10.1074/jbc.M206593200 . PMID   12167652.
  2. Tjernberg, L. O.; Callaway, D. J. E.; Tjernberg, A.; Hahne, S.; Lilliehöök, C.; Terenius, L.; Thyberg, J.; Nordstedt, C. (1999). "A molecular model of Alzheimer amyloid ß-peptide fibril formation". J Biol Chem . 274 (18): 12619–12625. doi: 10.1074/jbc.274.18.12619 . PMID   10212241.
  3. Bu Z, Callaway DJ (2011). "Proteins move! Protein dynamics and long-range allostery in cell signaling". In Donev R (ed.). Protein Structure and Diseases. Advances in Protein Chemistry and Structural Biology. Vol. 83. Academic Press. pp. 163–221. doi:10.1016/B978-0-12-381262-9.00005-7. ISBN   9780123812629. PMID   21570668.
  4. Bu, Z.; Biehl, R; Monkenbusch, M.; Richter, D.; Callaway, D. J. E. (2005). "Coupled protein domain motion in Taq polymerase revealed by neutron spin-echo spectroscopy". Proc Natl Acad Sci USA. 102 (49): 17646–17651. Bibcode:2005PNAS..10217646B. doi: 10.1073/pnas.0503388102 . PMC   1345721 . PMID   16306270.
  5. Callaway DJ, Nicholl ID, Shi B, Reyes G, Farago B, Bu Z (2024). "Nanoscale dynamics of the cadherin-catenin complex bound to vinculin revealed by neutron spin echo spectroscopy". Proceedings of the National Academy of Sciences of the United States of America. 129 (39). doi: 10.1073/pnas.2408459121 . PMC   11441495 . PMID   39298480.
  6. D. J. E. Callaway; A. Rahman (1982). "Microcanonical Ensemble Formulation of Lattice Gauge Theory". Phys. Rev. Lett. 49 (9): 613–616. Bibcode:1982PhRvL..49..613C. doi:10.1103/PhysRevLett.49.613.
  7. D. J. E. Callaway; A. Rahman (1983). "Lattice gauge theory in the microcanonical ensemble" (PDF). Phys. Rev. D. 28 (6): 1506–1514. Bibcode:1983PhRvD..28.1506C. doi:10.1103/PhysRevD.28.1506.
  8. D. J. E. Callaway; D. J. Maloof (1982). "Effective potential of lattice φ4 theory". Phys. Rev. D. D27 (2): 406–411. Bibcode:1983PhRvD..27..406C. doi:10.1103/PhysRevD.27.406.
  9. D. J. E. Callaway; F. Cooper; J. R. Klauder; H. A. Rose (1985). "Langevin simulations in Minkowski space". Nuclear Physics B. 262 (1): 19–32. Bibcode:1985NuPhB.262...19C. doi:10.1016/0550-3213(85)90061-6. S2CID   122569576.
  10. D. J. E. Callaway (1988). "Triviality Pursuit: Can Elementary Scalar Particles Exist?". Physics Reports . 167 (5): 241–320. Bibcode:1988PhR...167..241C. doi:10.1016/0370-1573(88)90008-7.
  11. D. J. E. Callaway (1984). "Non-triviality of gauge theories with elementary scalars and upper bounds on Higgs masses" (PDF). Nuclear Physics B. 233 (2): 189–203. Bibcode:1984NuPhB.233..189C. doi:10.1016/0550-3213(84)90410-3.
  12. Callaway, D. (1996). "Surface tension, hydrophobicity, and black holes: The entropic connection". Physical Review E. 53 (4): 3738–3744. arXiv: cond-mat/9601111 . Bibcode:1996PhRvE..53.3738C. doi:10.1103/PhysRevE.53.3738. PMID   9964684. S2CID   7115890.
  13. David J. E. Callaway (1990). "On the remarkable structure of the superconducting intermediate state". Nuclear Physics B . 344 (3): 627–645. Bibcode:1990NuPhB.344..627C. doi:10.1016/0550-3213(90)90672-Z.
  14. "Inspire".
  15. "David J. E. Callaway".
  16. Numerous expeditions
  17. "Eco-Challenge". Archived from the original on 2018-06-21. Retrieved 2018-06-20.