David Callaway

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David J. E. Callaway
David J. E. Callaway.jpg
David J. E. Callaway
Alma mater University of Washington; Caltech
Scientific career
Fields Biological physics
Institutions New York University School of Medicine
Thesis QCD and Weak Asymmetries in Lepton Pair Production  (1981)
Doctoral advisor Ernest M. Henley

David James Edward Callaway is a biological nanophysicist in the New York University School of Medicine, where he is professor and laboratory director. [1] He was trained as a theoretical physicist by Richard Feynman, Kip Thorne, and Cosmas Zachos, and was previously an associate professor at the Rockefeller University after positions at CERN and Los Alamos National Laboratory. Callaway's laboratory discovered potential therapeutics for Alzheimer's disease based upon apomorphine [2] after an earlier paper of his developed models of Alzheimer amyloid formation. [3] He has also initiated the study of protein domain dynamics [4] by neutron spin echo spectroscopy, providing a way to observe protein nanomachines in motion. [5] [6]

Contents

Previous work includes the invention of the microcanonical ensemble approach to lattice gauge theory with Aneesur Rahman, [7] [8] work on the convexity of the effective potential of quantum field theory, [9] work on Langevin dynamics in quantum field theory with John R. Klauder, [10] a monograph on quantum triviality, [11] constraints on the Higgs boson [12] and papers on black holes [13] and superconductors. [14] His work in these areas is highly cited and notable. [15] [16]

Expeditions and media appearances

Everest climbers receive Tengboche blessing. Ginette Harrison, Sir David Hempleman-Adams, David Callaway, Scott McIvor, Lee Nobmann, Brian Blessed. Everestblessings.jpg
Everest climbers receive Tengboche blessing. Ginette Harrison, Sir David Hempleman-Adams, David Callaway, Scott McIvor, Lee Nobmann, Brian Blessed.
Jean-Christophe Lafaille (left) and D J E Callaway at Shishapangma base camp Lafaille.gif
Jean-Christophe Lafaille (left) and D J E Callaway at Shishapangma base camp

Dr Callaway is an avid expedition mountaineer and polar explorer. [1] He was a competitor on the first Eco-Challenge. [17]

References

  1. 1 2 "David J E Callaway PhD".
  2. ↑ Lashuel, H. A.; Hartley, D. M.; Balakhaneh, D.; Aggarwal A.; Teichberg S.; Callaway, D. J. E. (2002). "New class of inhibitors of amyloid-beta fibril formation. Implications for the mechanism of pathogenesis in Alzheimer's disease". J Biol Chem . 277 (45): 42881–42890. doi: 10.1074/jbc.M206593200 . PMID   12167652.
  3. ↑ Tjernberg, L. O.; Callaway, D. J. E.; Tjernberg, A.; Hahne, S.; Lilliehöök, C.; Terenius, L.; Thyberg, J.; Nordstedt, C. (1999). "A molecular model of Alzheimer amyloid ß-peptide fibril formation". J Biol Chem . 274 (18): 12619–12625. doi: 10.1074/jbc.274.18.12619 . PMID   10212241.
  4. ↑ Bu Z, Callaway DJ (2011). "Proteins move! Protein dynamics and long-range allostery in cell signaling". In Donev R (ed.). Protein Structure and Diseases. Advances in Protein Chemistry and Structural Biology. Vol. 83. Academic Press. pp. 163–221. doi:10.1016/B978-0-12-381262-9.00005-7. ISBN   9780123812629. PMID   21570668.
  5. ↑ Bu, Z.; Biehl, R; Monkenbusch, M.; Richter, D.; Callaway, D. J. E. (2005). "Coupled protein domain motion in Taq polymerase revealed by neutron spin-echo spectroscopy". Proc Natl Acad Sci USA. 102 (49): 17646–17651. Bibcode:2005PNAS..10217646B. doi: 10.1073/pnas.0503388102 . PMC   1345721 . PMID   16306270.
  6. ↑ Callaway DJ, Nicholl ID, Shi B, Reyes G, Farago B, Bu Z (2024). "Nanoscale dynamics of the cadherin-catenin complex bound to vinculin revealed by neutron spin echo spectroscopy". Proceedings of the National Academy of Sciences of the United States of America. 129 (39). doi: 10.1073/pnas.2408459121 . PMC   11441495 . PMID   39298480.
  7. ↑ D. J. E. Callaway; A. Rahman (1982). "Microcanonical Ensemble Formulation of Lattice Gauge Theory". Phys. Rev. Lett. 49 (9): 613–616. Bibcode:1982PhRvL..49..613C. doi:10.1103/PhysRevLett.49.613.
  8. ↑ D. J. E. Callaway; A. Rahman (1983). "Lattice gauge theory in the microcanonical ensemble" (PDF). Phys. Rev. D. 28 (6): 1506–1514. Bibcode:1983PhRvD..28.1506C. doi:10.1103/PhysRevD.28.1506.
  9. ↑ D. J. E. Callaway; D. J. Maloof (1982). "Effective potential of lattice φ4 theory". Phys. Rev. D. D27 (2): 406–411. Bibcode:1983PhRvD..27..406C. doi:10.1103/PhysRevD.27.406.
  10. ↑ D. J. E. Callaway; F. Cooper; J. R. Klauder; H. A. Rose (1985). "Langevin simulations in Minkowski space". Nuclear Physics B. 262 (1): 19–32. Bibcode:1985NuPhB.262...19C. doi:10.1016/0550-3213(85)90061-6. S2CID   122569576.
  11. ↑ D. J. E. Callaway (1988). "Triviality Pursuit: Can Elementary Scalar Particles Exist?". Physics Reports . 167 (5): 241–320. Bibcode:1988PhR...167..241C. doi:10.1016/0370-1573(88)90008-7.
  12. ↑ D. J. E. Callaway (1984). "Non-triviality of gauge theories with elementary scalars and upper bounds on Higgs masses" (PDF). Nuclear Physics B. 233 (2): 189–203. Bibcode:1984NuPhB.233..189C. doi:10.1016/0550-3213(84)90410-3.
  13. ↑ Callaway, D. (1996). "Surface tension, hydrophobicity, and black holes: The entropic connection". Physical Review E. 53 (4): 3738–3744. arXiv: cond-mat/9601111 . Bibcode:1996PhRvE..53.3738C. doi:10.1103/PhysRevE.53.3738. PMID   9964684. S2CID   7115890.
  14. ↑ David J. E. Callaway (1990). "On the remarkable structure of the superconducting intermediate state". Nuclear Physics B . 344 (3): 627–645. Bibcode:1990NuPhB.344..627C. doi:10.1016/0550-3213(90)90672-Z.
  15. ↑ "Inspire".
  16. ↑ "David J. E. Callaway".
  17. ↑ "Eco-Challenge". Archived from the original on June 21, 2018. Retrieved June 20, 2018.


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