David J. Procter

Last updated
David Procter
Born
David John Procter

1970 (age 54–55)
Alma mater University of Leeds [1] (BSc., PhD)
Known for Samarium catalysis
Radical cascades
Sulfonium cross-coupling
Copper catalysis
Awards
Scientific career
Fields Organic Chemistry
Catalysis
InstitutionsThe University of Manchester
Thesis The development of a selenoxide-based asymmetric oxidation of sulfides to sulfoxides  (1995)
Doctoral advisor Prof. Christopher Rayner
Website www.proctergroupresearch.com

David John Procter is a British chemist and a Professor in the Department of Chemistry at The University of Manchester. [1] His research is based on organic chemistry and catalysis, specifically on radical cascades, sulfonium cross-coupling and copper catalysis. [4] [5]

Contents

Education

Proctercompleted his Bsc in 1992 at University of Leeds. [1] Upon graduation, he continued to read for his Doctor of Philosophy degree with Prof. Christopher Rayner on The development of a selenoxide-based asymmetric oxidation of sulfides to sulfoxides and successfully gained his PhD in 1995. [6]

Research and career

Procter completed his postdoctoral research with Prof. Robert Holton at Florida State University in Tallahassee, United States before moving to the University of Glasgow in 1997 as a Lecturer. [1] [7] In February 2004, he was promoted to the Senior Lecturer position and in September in the same year, was promoted to Reader in the Department of Chemistry at the University of Manchester. [1] He was promoted to Professor in October 2008. [7]

Procter's research is generally on organic synthesis and catalysis chemistry and is specifically based on radical cascades using the pivotal SET reagent samarium diiodide , metal-free sulfonium cross-coupling and copper catalysis. [4] [5]

Apart from research and lecturing, Procter has an established career fellowship (2015 - 2020) at the Engineering and Physical Sciences Research Council and an author profile in Angewandte Chemie. [8] [1] Procter was also a Leverhulme Trust Research Fellow (2013 - 2014) and is the lead author of Organic Synthesis using Samarium Diiodide: A practical guide. [1] [9] He was the Engineering and Physical Sciences Research Council panel chair in March 2017, January 2013 and September 2011 and was the Head of Organic Chemistry in the Department of Chemistry at the University of Manchester from 2011 to 2014. [8] In 2020, Procter became Head of the Department of Chemistry at the University of Manchester, a position he still holds as of 2025.

Notable work

The Procter research group has carried out a wide variety of research on the efficient construction of organic molecules. In 2015, he led a research on the synthesis of novel tri-cyclic organic compounds inspired by the antibacterial, pleuromutilin through SmII-mediated radical cyclization cascades of dialdehydes, prepared by a one-pot, copper catalyzed double organomagnesium addition to β‐chlorocyclohexenone. [10] This was the first time that important analogues of the antibacterial was prepared, which previously was unable to be synthesized using the naturally occurring product. [10]

The Procter research group has also invented metal-free cross-coupling processes with the aim to decrease the reliance of expensive and supply-risk transition metals. Examples include metal-free alkylation and arylation of benzothiophenes, [11] metal-free synthesis of benzothiophenes by twofold C–H functionalization, [12] and new reagents for metal-free C–H trifluoromethylthiolation in Trifluoromethyl sulfoxides. [4]

Awards and nominations

Major reviews and publications

Recent Publications by Prof. David J. Procter (2025–present): [4]

References

  1. 1 2 3 4 5 6 7 8 9 10 11 University of Manchester. "Dr David J. Procter" . Retrieved 6 June 2020.
  2. 1 2 "Bader Award" . Retrieved 6 June 2020.
  3. 1 2 Royal Society of Chemistry. "Bader Award Previous Winners" . Retrieved 6 June 2020.
  4. 1 2 3 4 "Procter Group Research" . Retrieved 6 June 2020.
  5. 1 2 "Research interests" . Retrieved 6 June 2020.
  6. ↑ Procter, David John (1995). The development of a selenoxide-based asymmetric oxidation of sulfides to sulfoxides (PhD thesis).(subscription required)
  7. 1 2 "Professor David Procter" . Retrieved 6 June 2020.
  8. 1 2 J. Procter, David (2017). "Author Profile: David J. Procter". Angewandte Chemie International Edition. 56 (19): 5152. doi:10.1002/anie.201610197.
  9. ↑ Procter, David J. (10 November 2009). Organic Synthesis using Samarium Diiodide: A practical guide. Royal Society of Chemistry. ISBN   978-1-84755-110-8.
  10. 1 2 Ruscoe, Rebecca E.; Fazakerley, Neal J.; Huang, Huanming; Flitsch, Sabine; Procter, David J. (2016). "Copper‐Catalyzed Double Additions and Radical Cyclization Cascades in the Re‐Engineering of the Antibacterial Pleuromutilin". Chem. Eur. J. 22 (1): 116–119. doi: 10.1002/chem.201504343 . PMC   4736435 . PMID   26527052.
  11. ↑ He, Zhen; Pulis, Alexander P; Perry, Gregory J. P.; Procter, David J. (2019). "Pummerer chemistry of benzothiophene S-oxides: Metal-free alkylation and arylation of benzothiophenes". Phosphorus, Sulfur, and Silicon and the Related Elements. 194 (7): 669–677. doi:10.1080/10426507.2019.1602626. S2CID   191173285.
  12. ↑ Yan, Jiajie; Pulis, Alexander P.; Perry, Gregory J. P.; Procter, David J. (2019). "Metal-Free Synthesis of Benzothiophenes by Twofold C–H Functionalization: Direct Access to Materials-Oriented Heteroaromatics". Angewandte Chemie International Edition. 58 (44): 15675–15679. doi:10.1002/anie.201908319. hdl: 2381/45605 . PMID   31479175. S2CID   201804146.
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