ECD (gene)

ECD
Identifiers
Aliases	ECD , GCR2, HSGT1, SGT1, ecdysoneless cell cycle regulator
External IDs	OMIM: 616464 MGI: 1917851 HomoloGene: 5256 GeneCards: ECD
Gene location (Human)
Chr.	Chromosome 10 (human)
End	73,169,055 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	20,398,189 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; Achilles tendon; ; islet of Langerhans; ; ganglionic eminence; ; popliteal artery; ; stromal cell of endometrium; ; bone marrow cells; ; gallbladder; ; internal globus pallidus; ; monocyte;
	Top expressed in
	internal carotid artery; ; external carotid artery; ; spermatocyte; ; primitive streak; ; hair follicle; ; lacrimal gland; ; parotid gland; ; knee joint; ; oocyte; ; quadriceps femoris muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transcription coactivator activity ; protein binding ; histone acetyltransferase binding ;
Cellular component	cytoplasm ; nucleus ; nucleoplasm ; R2TP complex ; cytosol ;
Biological process	regulation of G1/S transition of mitotic cell cycle ; cell population proliferation ; regulation of transcription, DNA-templated ; transcription by RNA polymerase II ; transcription, DNA-templated ; regulation of glycolytic process ; positive regulation of transcription by RNA polymerase II ; RNA splicing ; mRNA processing ;
	Sources:Amigo / QuickGO
Orthologs
	11319
	70601
	ENSG00000122882
	ENSMUSG00000021810
	O95905
	Q9CS74
	NM_001135752 ; NM_001135753 ; NM_007265
	NM_027475
	NP_001129224 ; NP_001129225 ; NP_009196
	NP_081751
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 18, 2022

Protein SGT1 is a protein that in humans is encoded by the ECD gene.^[5]^[6]^[7]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000122882 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021810 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Sato T, Jigami Y, Suzuki T, Uemura H (Feb 1999). "A human gene, hSGT1, can substitute for GCR2, which encodes a general regulatory factor of glycolytic gene expression in Saccharomyces cerevisiae". Mol Gen Genet. 260 (6): 535–40. doi:10.1007/s004380050926. PMID 9928932. S2CID 28511451.
↑ Gaziova I, Bonnette PC, Henrich VC, Jindra M (May 2004). "Cell-autonomous roles of the ecdysoneless gene in Drosophila development and oogenesis". Development. 131 (11): 2715–25. doi: 10.1242/dev.01143 . PMID 15128659.
↑ "Entrez Gene: ECD ecdysoneless homolog (Drosophila)".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Bork JM, Peters LM, Riazuddin S, et al. (2001). "Usher Syndrome 1D and Nonsyndromic Autosomal Recessive Deafness DFNB12 Are Caused by Allelic Mutations of the Novel Cadherin-Like Gene CDH23". Am. J. Hum. Genet. 68 (1): 26–37. doi:10.1086/316954. PMC 1234923 . PMID 11090341.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Nowotny M, Spiechowicz M, Jastrzebska B, et al. (2003). "Calcium-regulated interaction of Sgt1 with S100A6 (calcyclin) and other S100 proteins". J. Biol. Chem. 278 (29): 26923–8. doi: 10.1074/jbc.M211518200 . PMID 12746458.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID 17081983. S2CID 7827573.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000122882 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021810 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9928932-5] Sato T, Jigami Y, Suzuki T, Uemura H (Feb 1999). "A human gene, hSGT1, can substitute for GCR2, which encodes a general regulatory factor of glycolytic gene expression in Saccharomyces cerevisiae". Mol Gen Genet. 260 (6): 535–40. doi:10.1007/s004380050926. PMID 9928932. S2CID 28511451.

[pmid15128659-6] Gaziova I, Bonnette PC, Henrich VC, Jindra M (May 2004). "Cell-autonomous roles of the ecdysoneless gene in Drosophila development and oogenesis". Development. 131 (11): 2715–25. doi: 10.1242/dev.01143 . PMID 15128659.

[entrez-7] "Entrez Gene: ECD ecdysoneless homolog (Drosophila)".

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ECD (gene)

Related Research Articles

References

Further reading