ECOP

VOPP1
Identifiers
Aliases	VOPP1 , ECOP, GASP, vesicular, overexpressed in cancer, prosurvival protein 1, WBP1L2, WBP1/VOPP1 family member, VOPP1 WW domain binding protein
External IDs	OMIM: 611915 MGI: 2141658 HomoloGene: 12772 GeneCards: VOPP1
Gene location (Human)
Chr.	Chromosome 7 (human)
End	55,572,988 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	57,802,144 bp
RNA expression pattern
	Top expressed in
	thymus; ; lymph node; ; stromal cell of endometrium; ; pylorus; ; parotid gland; ; cecum; ; appendix; ; periodontal fiber; ; ganglionic eminence; ; cardia;
	Top expressed in
	saccule; ; otic placode; ; lacrimal gland; ; blood; ; retinal pigment epithelium; ; parotid gland; ; medullary collecting duct; ; seminal vesicula; ; olfactory epithelium; ; prefrontal cortex;
	More reference expression data
	n/a
Gene ontology
Molecular function	signal transducer activity ;
Cellular component	integral component of membrane ; integral component of organelle membrane ; endosome ; cytoplasmic vesicle membrane ; membrane ; cytoplasmic vesicle ;
Biological process	regulation of transcription, DNA-templated ; transcription, DNA-templated ;
	Sources:Amigo / QuickGO
Orthologs
	81552
	232023
	ENSG00000154978
	ENSMUSG00000037788
	Q96AW1
	Q8R1C3
NM_001284282 ; NM_001284283 ; NM_001284284 ; NM_030796 ; NM_001321242 ;
	NM_001321243 ; NM_001321244 ; NM_001321246 ; NM_001321247 ; NM_001321248 ; NM_001321249 ; NM_001321250 ; NM_001321251
	NM_146168
NP_001271211 ; NP_001271212 ; NP_001271213 ; NP_001308171 ; NP_001308172 ;
	NP_001308173 ; NP_001308175 ; NP_001308176 ; NP_001308177 ; NP_001308178 ; NP_001308179 ; NP_001308180 ; NP_110423
	NP_666280
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated December 30, 2023

EGFR-coamplified and overexpressed protein, also known as ECOP, is a human gene.^[5]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000154978 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000037788 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: ECOP EGFR-coamplified and overexpressed protein".

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Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948 . PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166.
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Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Matsuda A, Suzuki Y, Honda G, et al. (2003). "Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways". Oncogene. 22 (21): 3307–18. doi:10.1038/sj.onc.1206406. PMID 12761501. S2CID 38880905.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197. S2CID 27764390.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930 . PMID 15489336.
Park S, James CD (2005). "ECop (EGFR-coamplified and overexpressed protein), a novel protein, regulates NF-kappaB transcriptional activity and associated apoptotic response in an IkappaBalpha-dependent manner". Oncogene. 24 (15): 2495–502. doi:10.1038/sj.onc.1208496. PMID 15735698. S2CID 342531.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi: 10.1093/dnares/12.2.117 . PMID 16303743.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501 . PMID 16381901.
Brem H, Stojadinovic O, Diegelmann RF, et al. (2007). "Molecular Markers in Patients with Chronic Wounds to Guide Surgical Debridement". Mol. Med. 13 (1–2): 30–9. doi:10.2119/2006-00054.Brem. PMC 1869625 . PMID 17515955.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000154978 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000037788 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: ECOP EGFR-coamplified and overexpressed protein".

[1]

[2]

[3]

[4]

[5]

ECOP

Related Research Articles

References

Further reading