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Androgen insensitivity syndrome (AIS) is a condition involving the inability to respond to androgens, typically due to androgen receptor dysfunction.
Margaret Marian McPartland OBE, was an English and American jazz pianist, composer, and writer. She was the host of Marian McPartland's Piano Jazz on National Public Radio from 1978 to 2011.
XY complete gonadal dysgenesis, also known as Swyer syndrome, is a type of defect hypogonadism in a person whose karyotype is 46,XY. Though they typically have normal vulvas, the person has underdeveloped gonads, fibrous tissue termed "streak gonads", and if left untreated, will not experience puberty. The cause is a lack or inactivation of an SRY gene which is responsible for sexual differentiation. Pregnancy is sometimes possible in Swyer syndrome with assisted reproductive technology. The phenotype is usually similar to Turner syndrome (45,X0) due to a lack of X inactivation. The typical medical treatment is hormone replacement therapy. The syndrome was named after Gerald Swyer, an endocrinologist based in London.
Virilization or masculinization is the biological development of adult male characteristics in young males or females. Most of the changes of virilization are produced by androgens.
Chris Potter is an American jazz saxophonist, composer, and multi-instrumentalist.
Partial androgen insensitivity syndrome (PAIS) is a condition that results in the partial inability of the cell to respond to androgens. It is an X linked recessive condition. The partial unresponsiveness of the cell to the presence of androgenic hormones impairs the masculinization of male genitalia in the developing fetus, as well as the development of male secondary sexual characteristics at puberty, but does not significantly impair female genital or sexual development. As such, the insensitivity to androgens is clinically significant only when it occurs in individuals with a Y chromosome. Clinical features include ambiguous genitalia at birth and primary amenhorrhoea with clitoromegaly with inguinal masses. Müllerian structures are not present in the individual.
John Pisano was an American jazz guitarist.
Disorders of sex development (DSDs), also known as differences in sex development or variations in sex characteristics (VSC), are congenital conditions affecting the reproductive system, in which development of chromosomal, gonadal, or anatomical sex is atypical. DSDs is a clinical term used in some medical settings for what are otherwise referred to as intersex traits. The term was first introduced in 2006 and has not been without controversy.
Hanne Gaby Odiele is a Belgian model.
Complete androgen insensitivity syndrome (CAIS) is an AIS condition that results in the complete inability of the cell to respond to androgens. As such, the insensitivity to androgens is only clinically significant when it occurs in individuals who are exposed to significant amounts of testosterone at some point in their lives. The unresponsiveness of the cell to the presence of androgenic hormones prevents the masculinization of male genitalia in the developing fetus, as well as the development of male secondary sexual characteristics at puberty, but does allow, without significant impairment, female genital and sexual development in those with the condition.
Mild androgen insensitivity syndrome (MAIS) is a condition that results in a mild impairment of the cell's ability to respond to androgens. The degree of impairment is sufficient to impair spermatogenesis and / or the development of secondary sexual characteristics at puberty in males, but does not affect genital differentiation or development. Female genital and sexual development is not significantly affected by the insensitivity to androgens; as such, MAIS is only diagnosed in males. The clinical phenotype associated with MAIS is a normal male habitus with mild spermatogenic defect and / or reduced secondary terminal hair.
Tony Briffa is a Maltese-Australian politician who is notable for being the world's first known intersex and non-binary mayor and public officeholder.
Phoebe Hart is an Australian filmmaker, lecturer and intersex rights activist, born with Androgen Insensitivity Syndrome. Hart lectures in film, television and digital media at the Queensland University of Technology, and is principal of Hartflicker, a video and film production company. She is known particularly for her autobiographical road trip movie, Orchids, My Intersex Adventure.
Intersex, in humans and other animals, describes variations in sex characteristics including chromosomes, gonads, sex hormones, or genitals that, according to the UN Office of the High Commissioner for Human Rights, "do not fit typical binary notions of male or female bodies".
Small Luk is an intersex human rights activist and the first intersex person to openly acknowledge her biological sex characteristics in Hong Kong. She was born with partial androgen insensitivity syndrome (PAIS). Luk lived as a male for 36 years, and now identifies and lives as a woman, after changing her sex characteristics from intersex to female through gender-affirming surgery, upon doctors' advice to undergo the surgery because her type of PAIS would most likely have caused cancer.
None of the Above is a novel by I. W. Gregorio, published in 2015 about an adolescent intersex girl, Kristin, who discovers she has an intersex condition shortly after becoming Homecoming Queen.
Miriam van der Have is an intersex human rights activist and woman with androgen insensitivity syndrome. She is a co-founder and co-chair of OII Europe e.V in 2015, co-founder and managing director of NNID Foundation in the Netherlands and member of the ILGA board where she is Intersex Secretariat until spring 2019. Van der Have is also a documentary film maker and journalist.
Bonnie Hart is an Australian artist, film maker, and intersex human rights activist, born with androgen insensitivity syndrome and president of Intersex Peer Support Australia. Hart performs nationally and internationally, and speaks on intersex issues nationally and internationally. In 2016, Australia's Gay News Network included her in their "25 LGBTI people to watch in 2017".
Kimberly Zieselman is an attorney, human rights advocate, author, and intersex woman, with androgen insensitivity syndrome. She currently serves as executive director of interACT, and is a signatory of the Yogyakarta Principles plus 10. In 2020, her memoir XOXY was published.
References
- 1 2 "Atwood, Eden". Encyclopedia of Jazz. Archived from the original on March 25, 2012. Retrieved September 5, 2011.
- 1 2 3 "Eden Atwood". Montana Kids. Montana Office of Tourism. Retrieved August 9, 2011.
- ↑ Sawyers, June (26 April 1991). "Eden Atwood Is No Garden-variety Singer". Chicago Tribune. Retrieved 17 June 2013.
- 1 2 "Eded Atwood". All About Jazz. 24 October 2013. Retrieved 4 May 2017.
- ↑ Kilian, Michael (21 October 1992). "In Just 23 Years, Eden Atwood's Life Makes For The Juiciest Soap". tribunedigital-chicagotribune. Retrieved 3 May 2017.
- ↑ Today, Psychology. "Eden Atwood, Clinical Social Work/Therapist, Missoula, MT, 59801". Psychology Today. Retrieved 25 July 2022.
- ↑ Moore, Keith L.; T. V. N. Persaud; Mark G. Torchia (2011). "12". The Developing Human : Clinically Oriented Embryology (9th ed.). Philadelphia, Pennsylvania: Saunders/Elsevier. pp. 265–303. ISBN 978-1437720020.
- 1 2 "Androgen Insensitivity Syndrome (AIS)". Intersex Society of North America . Retrieved 17 June 2013.
- ↑ "Jazz Vocalist, Intersex Rights Advocate Eden Atwood joins film to bring soundtrack tunes!". Truth in Progress. July 10, 2014. Archived from the original on August 6, 2017. Retrieved 2017-08-05.
{{cite web}}: CS1 maint: unfit URL (link) - ↑ "Life and Intersex: An Interview with Jim Bruce and Eden Atwood of the Interface Project". Montana Public Radio. February 4, 2013. Archived from the original on August 6, 2017. Retrieved 2017-08-05.
- ↑ Henderson, Alex. "Today! - Eden Atwood". AllMusic. Retrieved 4 September 2020.
