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Edison T. Liu is an American chemist who is the former president and CEO of The Jackson Laboratory, and the former director of its NCI-designated Cancer Center (2012-2021). Before joining The Jackson Laboratory, he was the founding executive director of the Genome Institute of Singapore (GIS) (an A*STAR institute), chairman of the board of the Health Sciences Authority, and president of the Human Genome Organization (HUGO) (2007-2013). As the executive director of the GIS, he brought the institution to international prominence as one of the most productive genomics institutions in the world.
Between 1997 and 2001, he was the scientific director of the National Cancer Institute's Division of Clinical Sciences where he was in charge of the intramural clinical translational science programs. From 1987 to 1996, Liu was a faculty member at the University of North Carolina at Chapel Hill, where he was the director of the Lineberger Comprehensive Cancer Center's Specialized Program of Research Excellence in Breast Cancer; the director of the Laboratory of Molecular Epidemiology at UNC School of Public Health; chief of Medical Genetics; and the chair of the Correlative Science Committee of the national cooperative clinical trials group, CALGB.
Liu's scientific research has focused on the functional genomics of human cancers, particularly breast cancer (identifying the tandem duplicator phenotype genomic configuration [1] ), discovering new oncogenes (AXL family of receptor tyrosine kinases [2] ), and deciphering the dynamics of gene regulation on a genomic scale that modulates cancer biology. [3] His work has spanned basic to population sciences to translation to the clinic. He has authored over 320 scientific papers and reviews, and co-authored two books.
In his spare time, Liu [4] pursues jazz piano and composition, and writes for the lay public on science, medicine and society.
1983-1987 Postdoctoral Fellow - Dept. of Microbiology, University of California at San Francisco, CA (Dr. J. Michael Bishop)
1982-1985 Hematology Fellowship, University of California San Francisco, Moffitt Hospital
1980-1982 Oncology Fellowship, Stanford University
1979-1980 Residency, Barnes Hospital - Washington University School of Medicine
1978-1979 Internship, Barnes Hospital - Washington University in St. Louis
1973-1978 Stanford University School of Medicine, M.D.
1969-1973 Stanford University, B.S. Chemistry, Psychology
2021–present Professor, President Emeritus, and Honorary Fellow, The Jackson Laboratory
2011-2021 President and CEO, The Jackson Laboratory
2001-2011 Executive Director, Genome Institute of Singapore
2007–2011 Chairman, Governing Board Health Sciences Authority of Singapore
1996-2001 Director, Division of Clinical Sciences, National Cancer Institute, Bethesda, MD
1995-1996 Chief, Division of Medical Genetics, UNC School of Medicine
1995-1996 Professor, UNC Departments of Medicine, Epidemiology, Biochemistry and Biophysics.
1993-1995 Associate Professor, Departments of Medicine and Epidemiology and Biochemistry, University of North Carolina at Chapel Hill
1992-1996 Director, Specialized Program of Research Excellence in Breast Cancer (NIH-designated)
1987-1993 Assistant Professor in Medicine and Oncology, UNC School of Medicine
2018 Honorary Degree recipient, University of Southern Maine
2016 Honorary Degree recipient, Colby College [5]
2016 Elected Fellow, American Association for the Advancement of Science
2014 Chen Award for Distinguished Academic Achievement in Human Genetic and Genomic Research (from Human Genome Organization)
2010 Fellow, The Hastings Center
2008 Associate (Foreign) Member European Molecular Biology Organization (EMBO)
2007-2013 President, the Human Genome Organization (HUGO)
2007 Doctor of Medical Science honoris causa, awarded by Queen's University Belfast
2005 National Healthcare Group (NHG), Singapore, Distinguished Contributor Award
2003 Public Service Medal (National Day, 2003), for work in controlling SARS in Singapore (given by the Office of the President, Republic of Singapore)
2000 Rosenthal Award, AACR: for the discovery that HER-2 status determines response to adjuvant chemotherapy with doxorubicin
1999 Elected-Board of Directors, American Association for Cancer Research
1996 Brinker International Award for Breast Cancer Research - Basic Research Award
1995 American Society of Clinical Investigation (Membership)
1991-1996 Leukemia and Lymphoma Society Scholar
1985-1988 Clinical Investigator Award, National Cancer Institute, K08-CA01036-02, Preceptor: Dr. J. Michael Bishop.
1983-1985 Damon Runyan Cancer Fund Fellowship Preceptor: Dr. J. Michael Bishop (UCSF)
1973 Phi Beta Kappa
Cold Spring Harbor Laboratory (CSHL) is a private, non-profit institution with research programs focusing on cancer, neuroscience, plant biology, genomics, and quantitative biology. It is located in Laurel Hollow on Long Island, New York.
Marco A. Marra is a Distinguished Scientist and Director of Canada's Michael Smith Genome Sciences Centre at the BC Cancer Research Centre and Professor of Medical Genetics at the University of British Columbia (UBC). He also serves as UBC Canada Research Chair in Genome Science for the Canadian Institutes of Health Research and is an inductee in the Canadian Medical Hall of Fame. Marra has been instrumental in bringing genome science to Canada by demonstrating the pivotal role that genomics can play in human health and disease research.
The Human Genome Organisation (HUGO) is a non-profit organization founded in 1988. HUGO represents an international coordinating scientific body in response to initiatives such as the Human Genome Project. HUGO has four active committees, including the HUGO Gene Nomenclature Committee (HGNC), and the HUGO Committee on Ethics, Law and Society (CELS).
Axel Ullrich is a German cancer researcher and has been the director of the molecular biology department at the Max Planck Institute of Biochemistry in Martinsried, Germany since 1988. This department's research has primarily focused on signal transduction. Ullrich has received Hamdan Award for Medical Research Excellence, awarded by Sheikh Hamdan bin Rashid Al Maktoum Award for Medical Sciences, Dubai, United Arab Emirates in 2008 and Ullrich and his team received the Wolf Prize in 2010.
Mary-Claire King is an American geneticist. She was the first to show that breast cancer can be inherited due to mutations in the gene she called BRCA1. She studies human genetics and is particularly interested in genetic heterogeneity and complex traits. She studies the interaction of genetics and environmental influences and their effects on human conditions such as breast and ovarian cancer, inherited deafness, schizophrenia, HIV, systemic lupus erythematosus and rheumatoid arthritis. She has been the American Cancer Society Professor of the Department of Genome Sciences and of Medical Genetics in the Department of Medicine at the University of Washington since 1995.
Victor E. Velculescu is a Professor of Oncology and Co-Director of Cancer Biology at Johns Hopkins University School of Medicine. He is internationally known for his discoveries in genomics and cancer research.
Robert Bernard Darnell is an American neurooncologist and neuroscientist, founding director and former CEO of the New York Genome Center, the Robert and Harriet Heilbrunn Professor of Cancer Biology at The Rockefeller University, and an Investigator of the Howard Hughes Medical Institute. His research into rare autoimmune brain diseases led to the invention of the HITS-CLIP method to study RNA regulation, and he is developing ways to explore the regulatory portions—known as the "dark matter"—of the human genome.
Peter Boyle, FRSE FFPH FRCPS(Glas) FRCP(Edin) FMedSci, was a British epidemiologist. He conducted research on globalisation of cancer, where he showed the dramatic increase of cancer in low- and medium income countries.
Carlo La Vecchia is an Italian epidemiologist. He is doing research on chronic diseases, where he contributed to the understanding of the risks related to diet, tobacco, oral contraceptive use and occupational or environmental exposure to toxic substances in cancer and other chronic diseases development.
Eric D. Green is an American genomics researcher who had significant involvement in the Human Genome Project. He is the director of the National Human Genome Research Institute (NHGRI) at the National Institutes of Health (NIH), a position he has held since 2009.
Elaine R. Mardis is the co-executive director of the Institute for Genomic Medicine at Nationwide Children's Hospital, where she also serves as the Nationwide Foundation Endowed Chair in Genomic Medicine. She also is professor of pediatrics at the Ohio State University College of Medicine. Mardis’s research focuses on the genomic characterization of cancer and its implications for cancer medicine. She was part of the team that reported the first next-generation-based sequencing of a whole cancer genome, and participated extensively in The Cancer Genome Atlas (TCGA) and the Pediatric Cancer Genome Project (PCGP).
John Mendelsohn was a president of the University of Texas MD Anderson Cancer Center in Houston. He was an internationally recognized leader in cancer research.
Sir Bruce Anthony John Ponder FMedSci FAACR FRS FRCP is an English geneticist and cancer researcher. He is Emeritus Professor of Oncology at the University of Cambridge and former director of the Cancer Research UK Cambridge Institute and of the Cancer Research UK Cambridge Cancer Centre.
Andres Metspalu is an Estonian geneticist and member of the Estonian Academy of Sciences.
Ashok Venkitaraman is a British cancer researcher of Indian origin. He is the Director of the Cancer Science Institute of Singapore, a Distinguished Professor of Medicine at the National University of Singapore, and Program Director at A*STAR, Singapore. From 1998 to 2020, he was the inaugural holder of the Ursula Zoellner Professorship of Cancer Research at the University of Cambridge, a Professorial Fellow at Pembroke College, Cambridge, and from 2006 to 2019, was the Director of the Medical Research Council Cancer Unit.
Peter Propping was a German human geneticist.
Benita S. Katzenellenbogen née Schulman is an American physiologist and cell biologist at the University of Illinois at Urbana-Champaign. She has studied cancer, endocrinology, and women's health, focusing on nuclear receptors. She also dedicated efforts to focusing on improving the effectiveness of endocrine therapies in breast cancer.
Charis Eng was a Singaporean American physician-scientist and geneticist at the Cleveland Clinic, notable for identifying the PTEN gene. She was the chairwoman and founding director of the Genomic Medicine Institute of the Cleveland Clinic, founding director and attending clinical cancer geneticist of the institute's clinical component, the Center for Personalized Genetic Healthcare, and professor and vice chairwoman of the Department of Genetics and Genome Sciences at Case Western Reserve University School of Medicine.
David "Neil" Hayes is an American oncologist and physician–scientist. He is the Van Vleet Endowed Professor in Medical Oncology and the division chief of haematology and oncology at the University of Tennessee Health Science Center. As a result of his research, Hayes was elected a Member of the American Society for Clinical Investigation.
Howard L. McLeod is an American pharmacogeneticist and implementation scientist specialized in precision medicine.
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