Eilika Weber-Ban

Eilika Weber-Ban
Born	Eilika Ulrike Weber (1968-11-15) 15 November 1968 (age 56) Karlsruhe
Nationality	German
Alma mater	University of California at Riverside University of Tübingen
Scientific career
Institutions	ETH Zurich Yale University
Thesis	Catalytic and allosteric roles of monovalent metal ion cofactors in the tryptophan synthase bienzyme complex  (1996)
Website	Weber-Ban Lab

Eilika Weber-Ban (born 15 November 1968 in Karlsruhe) is a German biochemist. Her research considers protein degradation pathways. She was elected to the European Molecular Biology Organization in 2021.

Early life and education

Weber-Ban studied biochemistry at the University of Tübingen. She then received a Fulbright Program scholarship and went to the University of California at Riverside. Here she studied the tryptophan synthase bienzyme complex under the supervision of Michael Dunn. ^[1] She completed her graduate studies in 1996, and was awarded a Jane Coffin Childs Memorial Fund for Medical Research fellowship to join Arthur Horwich at Yale University.

Research and career

In 2001 she moved to the Institute for Molecular Biology and Biophysics at ETH Zurich. She was promoted to Professor in 2010. Her research considers the function and substrate recruitment mechanisms of bacterial degradation complexes, with a particular focus on Mycobacterium tuberculosis . ^{[2] [3]} Such bacteria rely on degradation pathways to survive the conditions inside the infected hosts. ^[2]

Weber-Ban was elected to the European Molecular Biology Organization in 2021. ^[4]

Select publications

• Eilika Weber-Ban; Reid BG; Miranker AD; Horwich AL (1 September 1999). "Global unfolding of a substrate protein by the Hsp100 chaperone ClpA". Nature . 401 (6748): 90–93. doi:10.1038/43481. ISSN   1476-4687. PMID   10485712. Wikidata   Q30322959.
• Jimena Weibezahn; Peter Tessarz; Christian Schlieker; et al. (1 November 2004). "Thermotolerance requires refolding of aggregated proteins by substrate translocation through the central pore of ClpB". Cell . 119 (5): 653–665. doi:10.1016/J.CELL.2004.11.027. ISSN   0092-8674. PMID   15550247. Wikidata   Q34369100.

• Markus Sutter; Daniel Boehringer; Sascha Gutmann; et al. (September 2008). "Structural basis of enzyme encapsulation into a bacterial nanocompartment". Nature Structural & Molecular Biology . 15 (9): 939–47. doi:10.1038/NSMB.1473. ISSN   1545-9993. PMID   19172747. Wikidata   Q27653528.

Personal life

Weber-Ban is married to Nenad Ban, a professor at ETH Zurich. ^{[5] [6]}

References

1. Weber, Eilika Ulrike (1993). Investigation of the mechanism of ligand-induced redistribution of intermediates in the tryptophan synthase bienzyme complex (Thesis). OCLC   32598928.
2. "Homepage". weber-ban-lab.ethz.ch. Retrieved 2021-06-23.
3. "Find people in the EMBO Communities". people.embo.org. Retrieved 2021-06-23.
4. "EMBO announces 64 newly elected members". idw-online.de. Retrieved 2021-06-23.
5. "Forscherkarriere und Familie verbinden". www.ethlife.ethz.ch. Retrieved 2021-06-23.
6. Pain, Elisabeth (2009-07-17). "A Career Revisiting Classical Biological Problems". Science | AAAS. Retrieved 2021-06-23.