Elizabeth McGraw

Last updated
Beth McGraw
Born
Elizabeth Ann McGraw
Alma mater Pennsylvania State University
University of Michigan
Scientific career
Fields Symbiosis
Evolution
Vector:virus interactions
Wolbachia
Institutions Monash University
University of Queensland
Yale University
Pennsylvania State University
Thesis Molecular evolution of invasive bacterial pathogens  (1998)
Website www.huck.psu.edu/people/elizabeth-mcgraw OOjs UI icon edit-ltr-progressive.svg

Elizabeth Ann McGraw is an American biologist who is a professor in entomology at Pennsylvania State University. [1] [2] She is the Director of the Center for Infectious Disease Dynamics and a Huck Scholar in Entomology. Her research investigates the bacterium Wolbachia as a strategy for biocontrol and to better understand the basis of its interactions with insects. [3] [4] [5] She was elected a Fellow of the American Society for Microbiology.

Contents

Early life and education

McGraw was an undergraduate biology student at the University of Michigan.[ when? ] She moved to Pennsylvania State University where she studied the evolution of virulence genes in human pathogens and was awarded a PhD in 1998. [6]

Research and career

After her PhD, she joined Yale University for her postdoctoral research, where she studied the Wolbachia insect system. She was particularly interested in being able to ask questions about the evolution of mutualism. She moved to the University of Queensland as a postdoctoral researcher.

McGraw was appointed to the faculty at the University of Queensland, then moved to Monash University as a Larkins Fellow in 2011, where she studied how bacteria affect host biology and how insects invest in response to a symbiont. [7] She has extensively studied the endosymbiont Wolbachia . Wolbachia prevents harmful pathogens replicating inside mosquitos, which may offer hope for biocontrol against mosquito-borne diseases. [8] Her research showed that when Wolbachia was inside mosquitoes it could prevent viruses from replicating. [9] She showed that Dengue virus could not become resistant to Wolbachia, and that Dengue viruses grown with Wolbachia were less effective at infecting mosquito cells and were less able to replicate. [9] [10]

In 2017, McGraw joined Pennsylvania State University as a professor in entomology. [11]

Awards and honors

McGraw was elected Fellow of the American Society for Microbiology in 2023. [8]

Selected publications

References

  1. ↑ Elizabeth McGraw publications indexed by Google Scholar OOjs UI icon edit-ltr-progressive.svg
  2. ↑ Elizabeth McGraw publications from Europe PubMed Central OOjs UI icon edit-ltr-progressive.svg
  3. 1 2 Luciano A Moreira; Iñaki Iturbe-Ormaetxe; Jason A Jeffery; et al. (1 December 2009). "A Wolbachia symbiont in Aedes aegypti limits infection with dengue, Chikungunya, and Plasmodium". Cell . 139 (7): 1268–1278. doi:10.1016/J.CELL.2009.11.042. ISSN   0092-8674. PMID   20064373. Wikidata   Q29616261.
  4. 1 2 Hoffmann AA; Montgomery BL; Popovici J; et al. (24 August 2011). "Successful establishment of Wolbachia in Aedes populations to suppress dengue transmission". Nature . 476 (7361): 454–7. doi:10.1038/NATURE10356. ISSN   1476-4687. PMID   21866160. Wikidata   Q29615114.
  5. 1 2 Martin Wu; Ling V Sun; Jessica Vamathevan; et al. (March 2004). "Phylogenomics of the reproductive parasite Wolbachia pipientis wMel: a streamlined genome overrun by mobile genetic elements". PLOS Biology . 2 (3): E69. doi: 10.1371/JOURNAL.PBIO.0020069 . ISSN   1544-9173. PMC   368164 . PMID   15024419. Wikidata   Q21563646.
  6. ↑ McGraw, Elizabeth Ann (1998). Molecular evolution of invasive bacterial pathogens (PhD thesis). Pennsylvania State University. OCLC   299248804. ProQuest   304463293.
  7. ↑ "Professor Elizabeth McGraw". zoo.ox.ac.uk. Retrieved 2023-02-28.
  8. 1 2 "McGraw elected as a Fellow of the American Academy of Microbiology | Penn State University". psu.edu. Retrieved 2023-02-28.
  9. 1 2 "Combating mosquito-borne diseases with bacteria | Penn State University". psu.edu. Retrieved 2023-02-28.
  10. ↑ "Global warming may limit spread of dengue fever, new research finds | Penn State University". psu.edu. Retrieved 2023-02-28.
  11. ↑ "People". vectorbiologygroup.com. Retrieved 2023-02-28.
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