FCRL2

FCRL2
Identifiers
Aliases	FCRL2 , CD307b, FCRH2, IFGP4, IRTA4, SPAP1, SPAP1A, SPAP1B, SPAP1C, Fc receptor like 2
External IDs	OMIM: 606509 HomoloGene: 57121 GeneCards: FCRL2
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q23.1 Start 157,745,733 bp [1] End 157,777,132 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in spleen lymph node appendix thymus superficial temporal artery blood bone marrow cells rectum duodenum cancellous bone n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component plasma membrane membrane integral component of membrane cell surface Biological process cell-cell signaling positive regulation of signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79368 n/a Ensembl ENSG00000132704 n/a UniProt Q96LA5 n/a RefSeq (mRNA) NM_001159488 NM_030764 NM_138738 NM_138739 n/a RefSeq (protein) NP_001152960 NP_110391 n/a Location (UCSC) Chr 1: 157.75 – 157.78 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Fc receptor-like protein 2 is a protein that in humans is encoded by the FCRL2 gene. ^{[3] [4]}

References

1. GRCh38: Ensembl release 89: ENSG00000132704 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. Xu MJ, Zhao R, Zhao ZJ (Feb 2001). "Molecular cloning and characterization of SPAP1, an inhibitory receptor". Biochem Biophys Res Commun. 280 (3): 768–75. doi:10.1006/bbrc.2000.4213. PMID   11162587.
4. "Entrez Gene: FCRL2 Fc receptor-like 2".

Further reading

• Davis RS, Wang YH, Kubagawa H, Cooper MD (2001). "Identification of a family of Fc receptor homologs with preferential B cell expression". Proc. Natl. Acad. Sci. U.S.A. 98 (17): 9772–7. Bibcode:2001PNAS...98.9772D. doi: 10.1073/pnas.171308498 . PMC   55528 . PMID   11493702.
• Miller I, Hatzivassiliou G, Cattoretti G, et al. (2002). "IRTAs: a new family of immunoglobulinlike receptors differentially expressed in B cells". Blood. 99 (8): 2662–9. doi: 10.1182/blood.V99.8.2662 . PMID   11929751.
• Guselnikov SV, Ershova SA, Mechetina LV, et al. (2002). "A family of highly diverse human and mouse genes structurally links leukocyte FcR, gp42 and PECAM-1". Immunogenetics. 54 (2): 87–95. doi:10.1007/s00251-002-0436-x. PMID   12037601. S2CID   9452957.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC   403697 . PMID   12975309.
• Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMC   2286551 . PMID   15340161.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi: 10.1038/nature04727 . PMID   16710414.
• Taylor AI, Gould HJ, Sutton BJ, Calvert RA (2007). "The first avian Ig-like Fc receptor family member combines features of mammalian FcR and FCRL". Immunogenetics. 59 (4): 323–8. doi:10.1007/s00251-007-0195-9. PMID   17273841. S2CID   1971426.